Knockdown resistance to DDT and pyrethroids: From target-site mutations to molecular modelling

Pest Management Science

Volumn 64, Issue 11, 2008, Pages 1126-1130

  Davies, T G Emyr ^a   O'Reilly, Andrias O ^b   Field, Linda M ^a   Wallace, B A ^b   Williamson, Martin S ^a  

^a ROTHAMSTED RESEARCH   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Computer modelling; DDT; IIS4 S5 linker; IIS6 helix; Pyrethroid; Voltage gated sodium channel

Indexed keywords

CHLORPHENOTANE; INSECTICIDE; PYRETHROID; SODIUM CHANNEL;

DDT; MOLECULAR ANALYSIS; MUTATION; PROTEIN; PYRETHROID;

ANIMAL; CHEMICAL STRUCTURE; DRUG EFFECT; GENETICS; INSECT; INSECTICIDE RESISTANCE; MUTATION; REVIEW;

ANIMALS; DDT; INSECTICIDE RESISTANCE; INSECTICIDES; INSECTS; MODELS, MOLECULAR; MUTATION; PYRETHRINS; SODIUM CHANNELS;

HEXAPODA;

EID: 55849109579     PISSN: 1526498X     EISSN: 15264998     Source Type: Journal    
DOI: 10.1002/ps.1617     Document Type: Review

References (30)

1. Glynne-Jones A, Pyrethrum. Pestic Outlook 12:195-198 (2001).
2. Mellanby K, The DDT Story. British Crop Protection Council, Alton, Hants, UK (1992).
3. Elliott M and Janes NF, Synthetic pyrethroids - a new class of insecticide. Chem Soc Reviews 7:473-505 (1978).
4. Narahashi T, Neuronal ion channels as the target sites of insecticides. Pharmacol Toxicol 78:1-14 (1996).
5. Soderlund DM and Bloomquist JR, Neurotoxic actions of pyrethroid insecticides. Ann Rev Entomol 34:77-96 (1989).
6. Hemingway J and Ranson H, Insecticide resistance in insect vectors of human disease. Ann Rev Entomol 45:371-391 (2000).
7. Keiding J, Problems of housefly (Musca domestica) control due to multi-resistance to insecticides. J Hyg Epidemiol Microbiol Immunol 19:340-355 (1975).
8. Georghiou GP, Overview of insecticide resistance, in Managing Resistance to Agrochemicals, ed. by Green MB, LeBaron HM and Moberg WK. American Chemical Society, Washington, DC, pp. 18-41 (1990).
9. Sawicki RM, Unusual response of DDT-resistant houseflies to carbinol analogues of DDT. Nature (London) 275:443-444 (1978).
10. Soderlund DM, Sodium channels, in Comprehensive Molecular Insect Science, Vol. 5, ed. by Gilbert LI, Iatrou K and Gill SS. Elsevier, Oxford, UK, pp. 1-24 (2005).
11. Davies TGE, Field LM, Usherwood PNR and Williamson MS, DDT, pyrethrins, pyrethroids and insect sodium channels. IUBMB-Life 59:151-162 (2007).
12. Dong K, Insect sodium channels and insecticide resistance. Invert Neurosci 7:17-30 (2007).
13. Williamson MS, Martinez-Torres D, Hick CA and Devonshire AL, Identification of mutations in the housefly para-type sodium channel gene associated with knockdown resistance (kdr) to pyrethroid insecticides. Mol Gen Genet 252:51-60 (1996).
14. Vais H, Williamson MS, Goodson SJ, Devonshire AL, Warmke JW, Usherwood PNR, et al, Activation of Drosophila sodium channels promotes modification by deltamethrin - reductions in affinity caused by knock-down resistance mutations. J Gen Physiol 115:305-318 (2000).
15. Schuler TH, Martinez-Torres D, Thompson AJ, Denholm I, Devonshire AL, Duce IR, et al, Toxicological, electrophysiological, and molecular characterisation of knockdown resistance to pyrethroid insecticides in the diamondback moth, Plutella xylostella (L.). Pestic Biochem Physiol 59:169-182 (1998).
16. Forcioli D, Frey B and Frey JE, High nucleotide diversity in the para-like voltage-sensitive sodium channel gene sequence in the western flower thrips, Frankliniella occidentalis (Thysanoptera: Thripidae). J Econ Entomol 95:838-84 (2002).
17. Bass C, Schroeder I, Turberg A, Field LMand Williamson MS, Identification of mutations associated with pyrethroid resistance in the para-type sodium channel of the cat flea, Ctenocephalides felis. Ins Biochem Mol Biol 34:1305-1313 (2004).
18. Lee SH, Yoon KS, Williamson MS, Goodson SJ, Takano-Lee M, Edman JD, et al, Molecular analysis of kdr-like resistance in permethrin-resistant strains of head lice, Pediculus capitis. Pestic Biochem Physiol 66:130-143 (2000).
19. Morin S, Williamson MS, Goodson SJ, Brown JK, Tabashnik BE and Dennehy TJ (2002). Mutations in the Bemisia tabaci para sodium channel gene associated with resistance to a pyrethroid plus organophosphate mixture. Ins Biochem Mol Biol 32:1781-1791.
20. Usherwood PNR, Davies TGE, Mellor IR, O'Reilly AO, Peng F, Vais H, et al, Mutations in DIIS5 and the DIIS4-S5 linker of Drosophila melanogaster sodium channel define binding domains for pyrethroids and DDT. FEBS Lett 581:5485-5492 (2007).
21. Tan J, Liu Z, Wang R, Huang ZY, Chen AC Gurevitz M, et al, Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding. Mol Pharmacol 67:513-522 (2005).
22. O'Reilly AO, Khambay BPS, Williamson MS, Field LM, Wallace BA and Davies TGE, Modelling insecticide binding sites at the voltage-gated sodium channel. Biochem J 396:255-263 (2006).
23. Usherwood PNR, Vais H, Khambay BPS, Davies TGE and Williamson MS, Sensitivity of the Drosophila para sodium channel to DDT is not lowered by the super-kdr mutation M918T on the IIS4-S5 linker that profoundly reduces sensitivity to permethrin and deltamethrin. FEBS Lett 579:6317-6325 (2005).
24. Vais H, Atkinson S, Pluteanu F, Goodson SJ, Devonshire AL, Williamson MS, et al, Mutations of the para sodium channel of Drosophila melanogaster identify putative binding sites for pyrethroids. Mol Pharmacol 64:914-922 (2003).
25. Khambay BPS and Jewess PJ, Pyrethroids, in Comprehensive Molecular Insect Science. Vol. 6, ed. by Gilbert LI, Iatrou K and Gill SS. Pergamon Press, Oxford, UK, pp. 1-29 (2004).
26. Khambay BPS, Farnham AW and Beddie DG, Relationships between pyrethroid structure and level of resistance in houseflies (Musca domestica L.), in Advances in the Chemistry of Insect Control III, ed. by Briggs GG. The Royal Society of Chemistry, Cambridge, UK, pp. 117-126 (1994).
27. + channel and its dependence on the lipid membrane. PNAS 102:15441-15446 (2005).
28. Rinkevich FD, Zhang L, Hamm RL, Brady SG, Lazzaro BP and Scott JG, Frequencies of the pyrethroid resistance alleles of Vssc1 and CYP6D1 in houseflies from the eastern United States. Ins Mol Biol 15:157-167 (2006).
29. Ranson H, Jensen B, Vulule JM, Wang X, Hemingway J and Collins FH, Identification of a point mutation in the voltage-gated sodium channel gene of Kenyan Anopheles gambiae associated with resistance to DDT and pyrethroids. Ins Mol Biol 9:491-497 (2000).
30. Tan J, Liu Z, Tsai TD, Valles SM, Goldin AL and Dong K, Novel sodium channel gene mutations in Blattella germanica reduce the sensitivity of expressed channels to deltamethrin. Ins Biochem Mol Biol 32:445-454 (2002).