Structural insights into the evolution of a non-biological protein: Importance of surface residues in protein fold optimization

PLoS ONE

Volumn 2, Issue 5, 2007, Pages

  Smith, Matthew D ^a   Rosenow, Matthew A ^a   Wang, Meltian ^a   Allen, James P ^a   Szostak, Jack W ^b   Chaput, John C ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BINDING PROTEIN; PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; IN VITRO SELECTION; LIGAND BINDING; MOLECULAR EVOLUTION; MUTATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SOLUBILITY; STRUCTURE ANALYSIS; THERMOSTABILITY; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR GENETICS; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN FOLDING; PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 55849103128     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000467     Document Type: Article

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