메뉴 건너뛰기




Volumn 28, Issue 5 A, 2008, Pages 2691-2696

Inotodiol, a lanostane triterpenoid, from Inonotus obliquus inhibits cell proliferation through caspase-3-dependent apoptosis

Author keywords

Apoptosis; Caspase 3; Cell proliferation; Inotodiol; Lanostane triterpenoids

Indexed keywords

CASPASE 3; CASPASE 3 INHIBITOR; CASPASE 7; CHLOROFORM; INONOTUS OBLIQUUS EXTRACT; INOTODIOL; TRITERPENOID; UNCLASSIFIED DRUG;

EID: 55749109726     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (76)

References (21)
  • 2
    • 0026071601 scopus 로고
    • Fungi in Khanty folk medicine
    • Saar M: Fungi in Khanty folk medicine. J Ethnopharmacol 31: 175-179, 1991.
    • (1991) J Ethnopharmacol , vol.31 , pp. 175-179
    • Saar, M.1
  • 3
    • 0011594846 scopus 로고    scopus 로고
    • Antitumor and hypoglycemic activities of polysaccharides from the sclerotia and mycelia of Inonotus obliquus (Pers:Fr) Pil. (Aphyllophoromycetidae)
    • Mizuno T, Zhuang C, Abe K, Okamoto H, Kiho T, Ukai S, Leclerc S and Meijer L: Antitumor and hypoglycemic activities of polysaccharides from the sclerotia and mycelia of Inonotus obliquus (Pers:Fr) Pil. (Aphyllophoromycetidae). Int J Med Mushr 1: 301-316, 1999.
    • (1999) Int J Med Mushr , vol.1 , pp. 301-316
    • Mizuno, T.1    Zhuang, C.2    Abe, K.3    Okamoto, H.4    Kiho, T.5    Ukai, S.6    Leclerc, S.7    Meijer, L.8
  • 4
    • 0037210695 scopus 로고    scopus 로고
    • Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides
    • Wasser SP: Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl Microbiol Biotechnol 60: 258-274, 2002.
    • (2002) Appl Microbiol Biotechnol , vol.60 , pp. 258-274
    • Wasser, S.P.1
  • 5
    • 9644252734 scopus 로고    scopus 로고
    • Antioxidant effect of Inonotus obliquus
    • Cui Y, Kim DS and Park KC: Antioxidant effect of Inonotus obliquus. J Ethnopharmacol 96: 79-85, 2005.
    • (2005) J Ethnopharmacol , vol.96 , pp. 79-85
    • Cui, Y.1    Kim, D.S.2    Park, K.C.3
  • 6
    • 36049030819 scopus 로고    scopus 로고
    • New antioxidant polyphenols from the medicinal mushroom Inonotus obliquus
    • Lee IK, Kim YS, Jang YW, Jung JY and Yun BS: New antioxidant polyphenols from the medicinal mushroom Inonotus obliquus. Bioorg Med Chem Lett 17: 6678-6681, 2007.
    • (2007) Bioorg Med Chem Lett , vol.17 , pp. 6678-6681
    • Lee, I.K.1    Kim, Y.S.2    Jang, Y.W.3    Jung, J.Y.4    Yun, B.S.5
  • 7
    • 0033252460 scopus 로고    scopus 로고
    • HIV-1 protease inhibition and anti-HIV effect of natural and synthetic water-soluble lignin-like substances
    • Ichimura T, Otake T, Mori H and Maruyama S: HIV-1 protease inhibition and anti-HIV effect of natural and synthetic water-soluble lignin-like substances. Biosci Biotechnol Biochem 63: 2202-2204, 1999.
    • (1999) Biosci Biotechnol Biochem , vol.63 , pp. 2202-2204
    • Ichimura, T.1    Otake, T.2    Mori, H.3    Maruyama, S.4
  • 8
    • 0028171109 scopus 로고
    • Antifungal activity of cysteine, its effect on C-21 oxygenated lanosterol derivatives and other lipids in Inonotus obliquus, in vitro
    • Kahlos K and Tikka VH: Antifungal activity of cysteine, its effect on C-21 oxygenated lanosterol derivatives and other lipids in Inonotus obliquus, in vitro. Appl Microbiol Biotechnol 42: 385-390, 1994.
    • (1994) Appl Microbiol Biotechnol , vol.42 , pp. 385-390
    • Kahlos, K.1    Tikka, V.H.2
  • 9
    • 24644477113 scopus 로고    scopus 로고
    • In vivo and in vitro anti-inflammatory and anti-nociceptive effects of the methanol extract of Inonotus obliquus
    • Park YM, Won JH, Kim YH, Choi JW, Park HJ and Lee KT: In vivo and in vitro anti-inflammatory and anti-nociceptive effects of the methanol extract of Inonotus obliquus. J Ethnopharmacol 101: 120-128, 2005.
    • (2005) J Ethnopharmacol , vol.101 , pp. 120-128
    • Park, Y.M.1    Won, J.H.2    Kim, Y.H.3    Choi, J.W.4    Park, H.J.5    Lee, K.T.6
  • 10
    • 33750964698 scopus 로고    scopus 로고
    • Structure determination of inonotsuoxides A and B and in vivo antitumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus
    • Nakata T, Yamada T, Taji S, Ohishi H, Wada S, Tokuda H, Sakuma K and Tanaka R: Structure determination of inonotsuoxides A and B and in vivo antitumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus. Bioorg Med Chem 15: 257-264, 2007.
    • (2007) Bioorg Med Chem , vol.15 , pp. 257-264
    • Nakata, T.1    Yamada, T.2    Taji, S.3    Ohishi, H.4    Wada, S.5    Tokuda, H.6    Sakuma, K.7    Tanaka, R.8
  • 12
    • 0023256505 scopus 로고
    • Antitumor activity of some compounds and fractions from an n-hexane extract of Inonotus obliquus
    • Kahlos K, Kangas L and Hiltunen R: Antitumor activity of some compounds and fractions from an n-hexane extract of Inonotus obliquus. Acta Pharm Fennica 96: 33-40, 1987.
    • (1987) Acta Pharm Fennica , vol.96 , pp. 33-40
    • Kahlos, K.1    Kangas, L.2    Hiltunen, R.3
  • 14
    • 33745303556 scopus 로고    scopus 로고
    • Anticancer effect and structural characterization of endopolysaccharide from cultivated mycelia of Inonotus obliquus
    • Kim YO, Park HW, Kim JH, Lee JY, Moon SH and Shin CS: Anticancer effect and structural characterization of endopolysaccharide from cultivated mycelia of Inonotus obliquus. Life Sci 79: 72-80, 2006.
    • (2006) Life Sci , vol.79 , pp. 72-80
    • Kim, Y.O.1    Park, H.W.2    Kim, J.H.3    Lee, J.Y.4    Moon, S.H.5    Shin, C.S.6
  • 15
    • 0028323164 scopus 로고
    • A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry
    • Gong J, Traganos F and Darzynkiewicz Z: A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry. Anal Biochem 218: 314-319, 1994.
    • (1994) Anal Biochem , vol.218 , pp. 314-319
    • Gong, J.1    Traganos, F.2    Darzynkiewicz, Z.3
  • 16
    • 11844249348 scopus 로고    scopus 로고
    • Lanostanoid triterpenes from Laetiporus sulphureus and apoptosis induction on HL-60 human myeloid leukemia cells
    • Léon F, Quintana J, Rivera A, Estévez F and Bermejo J: Lanostanoid triterpenes from Laetiporus sulphureus and apoptosis induction on HL-60 human myeloid leukemia cells. J Nat Prod 67: 2008-2011, 2004.
    • (2004) J Nat Prod , vol.67 , pp. 2008-2011
    • Léon, F.1    Quintana, J.2    Rivera, A.3    Estévez, F.4    Bermejo, J.5
  • 17
    • 33845231348 scopus 로고    scopus 로고
    • Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondriamediated apoptosis in lung cancer cells
    • Tang W, Liu JW, Zhao WM, Wei DZ and Zhong JJ: Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondriamediated apoptosis in lung cancer cells. Life Sci 80: 205-211, 2006.
    • (2006) Life Sci , vol.80 , pp. 205-211
    • Tang, W.1    Liu, J.W.2    Zhao, W.M.3    Wei, D.Z.4    Zhong, J.J.5
  • 19
    • 0344389027 scopus 로고    scopus 로고
    • Caspases: The proteases of the apoptotic pathway
    • Nuñez G, Benedict MA, Hu Y and Inohara N: Caspases: the proteases of the apoptotic pathway. Oncogene 17: 3237-3245, 1998.
    • (1998) Oncogene , vol.17 , pp. 3237-3245
    • Nuñez, G.1    Benedict, M.A.2    Hu, Y.3    Inohara, N.4
  • 20
    • 0031889132 scopus 로고    scopus 로고
    • Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
    • Sakahira H, Enari M and Nagata S: Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391: 96-99, 1998.
    • (1998) Nature , vol.391 , pp. 96-99
    • Sakahira, H.1    Enari, M.2    Nagata, S.3
  • 21
    • 0030916417 scopus 로고    scopus 로고
    • DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
    • Liu X, Zou H, Slaughter C and Wang X: DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89: 175-184, 1997.
    • (1997) Cell , vol.89 , pp. 175-184
    • Liu, X.1    Zou, H.2    Slaughter, C.3    Wang, X.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.