Development of a liquid enzyme-based ceruminolytic product

Journal of Pharmaceutical Sciences

Volumn 97, Issue 11, 2008, Pages 4970-4982

  Jimenez, Nuria ^a,b   Garcia, Marisa L ^b   Galan, Javier ^a   Vallet, Alberto ^a   Owen, Geoffrey R ^c   Michael Wall, G ^c  

^a Department of Pharmaceutical Development   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c ALCON RESEARCH LTD   (United States)

Author keywords

Cerumen; Ceruminolytic; Ear wax; Methyl trypsin; Protease; Sodium bicarbonate

Indexed keywords

BENZALKONIUM CHLORIDE; BICARBONATE; CERUMENEX EAR DROPS; CERUMINOLYTIC AGENT; CITRATE SODIUM; CITRIC ACID; DISODIUM HYDROGEN PHOSPHATE; METHYL TRYPSIN; MURINE EAR WAX REMOVAL DROPS; POTASSIUM DIHYDROGEN PHOSPHATE; SODIUM HYDROXIDE; TETRONIC 1304; TRYPSIN; UNCLASSIFIED DRUG;

ARTICLE; DRUG FORMULATION; DRUG PACKAGING; DRUG STABILITY; ENZYME STABILITY; HUMAN; IN VITRO STUDY; PH; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; ROOM TEMPERATURE; SHELF LIFE; SPECTROPHOTOMETRY;

EID: 55749086975     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21337     Document Type: Article

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