Long-term remission in a patient with hepatosplenic gammadelta T cell lymphoma treated with bortezomib and high-dose CHOP-like chemotherapy followed by autologous peripheral stem cell transplantation

Annals of Hematology

Volumn 87, Issue 12, 2008, Pages 1023-1024

  Otrock, Zaher K ^a   Hatoum, Hassan A ^a   Salem, Ziad M ^a   Tawil, Ayman ^a   Mahfouz, Rami A ^a   Zaatari, Ghazi S ^a   Bazarbachi, Ali ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; BORTEZOMIB; CARMUSTINE; CD2 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD45RO ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; CYCLOPHOSPHAMIDE; CYTARABINE; DOXORUBICIN; ETOPOSIDE; GEMCITABINE; GRANULOCYTE COLONY STIMULATING FACTOR; HLA DR ANTIGEN; MELPHALAN; NAVELBINE; PLATINUM COMPLEX; PREDNISONE; T LYMPHOCYTE RECEPTOR DELTA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN; VINCRISTINE;

ADULT; AUTOLOGOUS PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; CANCER REGRESSION; CANCER RELAPSE; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; DEATH; DRUG MEGADOSE; DRUG WITHDRAWAL; FEBRILE NEUTROPENIA; FEMALE; FLOW CYTOMETRY; FOLLOW UP; HEPATOSPLENOMEGALY; HUMAN; LETTER; LIVER BIOPSY; MULTIPLE CYCLE TREATMENT; NEUROTOXICITY; PRIORITY JOURNAL; SEPSIS; T CELL LYMPHOMA;

ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BORONIC ACIDS; CYCLOPHOSPHAMIDE; DOXORUBICIN; FATAL OUTCOME; FEMALE; HUMANS; LYMPHOMA, T-CELL, PERIPHERAL; NEOPLASM RECURRENCE, LOCAL; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; PREDNISONE; PROTEASE INHIBITORS; PYRAZINES; REMISSION INDUCTION; T-LYMPHOCYTE SUBSETS; TRANSPLANTATION, AUTOLOGOUS; VINCRISTINE;

EID: 55649103248     PISSN: 09395555     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00277-008-0523-7     Document Type: Letter

References (5)

1. Belhadj K, Reyes F, Farcet JP, Tilly H, Bastard C, Angonin R et al (2003) Hepatosplenic gammadelta T-cell lymphoma is a rare clinicopathologic entity with poor outcome: Report on a series of 21 patients. Blood 102:4261-4269 doi: 10.1182/blood-2003-05-1675
2. Vega F, Medeiros LJ, Gaulard P (2007) Hepatosplenic and other gammadelta T-cell lymphomas. Am J Clin Pathol 127:869-880 doi: 10.1309/ LRKX8CE7GVPCR1FT
3. de Wolf-Peeters C, Achten R (2000) gammadelta T-cell lymphomas: A homogeneous entity? Histopathology 36:294-305 doi: 10.1046/ j.1365-2559.2000.00893.x
4. Park DJ, Lenz HJ (2004) The role of proteasome inhibitors in solid tumors. Ann Med 36:296-303 doi: 10.1080/07853890410029031
5. Nasr R, El-Sabban ME, Karam JA, Dbaibo G, Kfoury Y, Arnulf B et al (2005) Efficacy and mechanism of action of the proteasome inhibitor PS-341 in T-cell lymphomas and HTLV-I associated adult T-cell leukemia/ lymphoma. Oncogene 24:419-430 doi: 10.1038/sj.onc.1208212