TGF-β gene polymorphisms and primary vesicoureteral reflux in childhood

Pediatric Nephrology

Volumn 23, Issue 12, 2008, Pages 2195-2200

  Kowalewska Pietrzak, Magdalena ^a   Klich, Izabela ^a   Mlynarski, Wojciech ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Renal scarring; TGF gene polymorphisms; Vesicoureteral reflux

Indexed keywords

LEUCINE; PROLINE; SUCCIMER TC 99M; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENE LOCATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HOMOZYGOTE; HOSPITAL BASED CASE CONTROL STUDY; HUMAN; KIDNEY SCAR; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; RISK FACTOR; SCHOOL CHILD; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; VESICOURETERAL REFLUX; ADOLESCENT; CASE CONTROL STUDY; CHILD; DISEASE COURSE; GENETIC PREDISPOSITION; GENETICS; INFANT; KIDNEY; PATHOLOGY; PRESCHOOL CHILD; SCAR; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CICATRIX; DISEASE PROGRESSION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HOMOZYGOTE; HUMANS; INFANT; KIDNEY; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; TRANSFORMING GROWTH FACTOR BETA1; VESICO-URETERAL REFLUX;

EID: 55649092460     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-008-0927-6     Document Type: Article

References (32)

1. Blobe GC, Schiemann WP, Lodish HF (2000) Role of transforming growth factor beta in human disease. N Engl J Med 342:1350-1358
2. Border WA, Noble NA (1994) Transforming growth factor β in tissue fibrosis. N Engl J Med 331:1286-1292
3. Ihn H (2002) Pathogenesis of fibrosis: The role of TGF-(beta) and CTGF. Curr Opin Rheumatol 14:681-685
4. Fujii D, Brissenden JE, Derynck R, Francke U (1986) Transforming growth factor beta gene maps to human chromosome 19 long arm and to mouse chromosome 7. Somat Cell Mol Genet 12:281-288
5. Grainger DJ, Heathcote K, Chiano M, Snieder H, Kemp PR, Metcalfe JC, Carter ND, Spetcor TD (1999) Genetic control of the circulating concentration of transforming growth factor type β1. Hum Mol Genet 8:93-97
6. Shah R, Rahaman B, Hurley CK, Posch P (2006) Allelic diversity in the TGFβ regulatory region: Characterization of novel functional single nucleotide polymorphisms. Hum Genet 119:61-74
7. Gou Z, Binswanger U, Knoflach A (2002) Role of codon 10 and codon 25 polymorphisms on TGF-β1 gene expression and protein synthesis in stable renal allograft recipients. Transplant Proc 34:2904-2906
8. Chow KM, Szeto CC, Poon P, Lau WY, Lai FM, Li PK (2005) Transforming growth factor-β1 gene polymorphism in renal transplant recipients. Ren Fail 27:671-675
9. Silverman ES, Palmer LJ, Subramaniam V, Hallock A, Mathew S, Vallone J, Faffe DS, Shikanai T, Raby BA, Weiss ST, Shore SA (2004) Transforming growth factor beta(1) promoter polymorphism C-509T is associated with asthma. Am J Resp Crit Care Med 169:214-219
10. Gressner AM, Weiskirchen R, Breitkopf K, Dooley S (2002) Roles of TGF-beta in hepatic fibrosis. Front Biosci 7:d793-d807
11. Ng DP, Warram JH, Krolewski AS (2003) TGF- beta 1 as a genetic susceptibility locus for advanced diabetic nephropathy in type 1 diabetes mellitus: An investigation of multiple known DNA sequence variants. Am J Kidney Dis 41:22-28
12. Patel A, Scott WR, Lympanyt TA, Rippin JD, Gill GV, Barnett AH, Bain SC, the Warren 3/UK GoKind Study Group (2005) The TGF-β1 gene codon 10 polymprphism contributes to the genetic predisposition to nephropathy in Type 1 diabetes. Diabet Med 22:69-73
13. Salah Khalil M, El Nahas AM, Blakemore AIF (2005) Transforming growth factor-β1 SNPs: Genetic and phenotypic correlations in progressive kidney insufficiency. Nephron Exp Nephrol 101:e31-e41
14. Lahdes-Vasama T, Niskanen K, Rönnholm K (2006) Outcome of kidneys in patients treated for vesicoureteral reflux (VUR) during childhood. Nephrol Dial Transplant 21:2491-2497
15. Smellie JM, Prescod NP, Shaw PJ, Ridson RA, Bryant TN (1998) Childhood reflux and urinary infections: A follow-up of 10-41 years in 226 adults. Pediatr Nephrol 12:727-736
16. Mehls O, Rigden S, Ehrich JH, Berthoux F, Jones EHP, Valderrábano F (1996) Report on management of renal failure in Europe XXV, 1994. The child-adult interface. Nephrol Dial Transplant 11:22-23
17. Cotton SA, Gbadegesin RA, Williams S, Brenchley PEC, Webb NJA (2002) Role of TGF-β1 in renal parenchymal scarring following childhood urinary tract infection. Kidney Int 61:61-67
18. Lee-Chen GJ, Liu KP, Lai YC, Juang HS, Huang SY, Lin CY (2004) Significance of tissue kallikrein promoter and transforming growth factor-β1 polymorphisms with renal progression in children with vesicoureteral reflux. Kidney Int 65:1467-1472
19. Solari V, Owen D, Puri P (2005) Association of transforming growth factor-β1 gene polymorphism with reflux nephropathy. J Urol 174:1609-1611
20. Yim HE, Bae IS, Yoo KH, Hong YS, Lee JW (2007) Genetic control of VEGF and TGF-(beta)1 gene polymorphism in childhood urinary tract infection and vesicoureteral reflux. Pediatr Res 62:183-187
21. International Reflux Study Committee (1981) Medical versus surgical treatment of primary vesicoureteral reflux: A prospective international reflux study in children. J Urol 125:277-283
22. 99mTechnetium-unitiol complex, a new pharmaceutical for kidney scintigraphy. Nuklearmedizin 15:282-286
23. Gadzicki M, Bieńkiewicz M, Młodkowska E, Knapska M, Kowalewska-Pietrzak M, Kuśmierek J (2004) Cortical scintigraphy in the evaluation of renal defects in children with vesicoureteral reflux - optimization of the procedure and study interpretation. Nucl Med Rev Cent East Eur 7:157-164
24. Jakobsson B, Svensson L (1997) Transient pyelonephritic changes on 99 m Technetium - dimercaptosuccinic acid scan for at least five months after infection. Acta Pediatr 86:803-807
25. Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265
26. Wenneström M, Hansson S, Jodal U, Stockland E (1998) Disappereance of Vesicoureteral Reflux in Children. Arch Pediatr Adolesc Med 152:879-883
27. The International HapMap Consortium (2007) A second generation human haplotype map of over 3.1 million SNPs. Nature 449:851-861
28. Clark AT, Young RJ, Bertram JF (2001) In vitro studies on the roles of transforming growth factor-β1 in rat metanephric development. Kidney Int 59:1641-1653
29. Yang SP, Woolf AS, Yuan HT, Scott RJ, Ridson RA, O'Hare MJ, Winyard PJD (2000) Potential biological role of transforming growth factor-β1 in human congenital kidney malformations. Am J Pathol 157:1633-1647
30. Murawski IJ, Gupta IR (2006) Vesicoureteric reflux and renal malformations: A developmental problem. Clin Genet 69:105-117
31. Wan J, Greenfield SP, Manyan NG, Zerin M, Ritchey ML, Bloom D (1996) Sibling reflux: A dual centre retrospective study. J Urol 156:677-679
32. International Reflux Study in Children (1992) Five year study of medical or surgical treatment in children with severe reflux: Radiological findings. Pediatr Nephrol 6:223-230