Electrocardiographic abnormalities in opiate addicts

Addiction

Volumn 103, Issue 12, 2008, Pages 1987-1993

  Wallner, Christina ^a,d   Stöllberger, Claudia ^b   Hlavin, Anton ^a   Finsterer, Josef ^b   Hager, Isabella ^c   Hermann, Peter ^a  

^a OTTO WAGNER HOSPITAL   (Austria)

^b KRANKENANSTALT RUDOLFSTIFTUNG   (Austria)

^c UNIVERSITY OF VIENNA   (Austria)

^d Otto Wagner Spital   (Austria)

Author keywords

Buprenorphine; ECG; Heart; Methadone maintenance treatment; Opiate addiction; Slow releasing morphine

Indexed keywords

BENZODIAZEPINE DERIVATIVE; BUPRENORPHINE; CANNABIS; CODEINE; METHADONE; MORPHINE; OPIATE;

ADOLESCENT; ADULT; ARTICLE; ECG ABNORMALITY; ELECTROCARDIOGRAPHY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; METHADONE TREATMENT; MISSING R PROGRESSION; OPIATE ADDICTION; QT PROLONGATION; R WAVE; SEIZURE; SEX DIFFERENCE; ST SEGMENT; ST SEGMENT ABNORMALITY; TALL R WAVE; TALL S WAVE; URINALYSIS;

ADOLESCENT; ADULT; ARRHYTHMIAS, CARDIAC; CROSS-SECTIONAL STUDIES; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; MALE; METHADONE; MIDDLE AGED; NARCOTIC ANTAGONISTS; OPIOID-RELATED DISORDERS; YOUNG ADULT;

EID: 55649083353     PISSN: 09652140     EISSN: 13600443     Source Type: Journal    
DOI: 10.1111/j.1360-0443.2008.02333.x     Document Type: Article

References (29)

1. Dressler F. A., Roberts W. C. Modes of death and types of cardiac diseases in opiate addicts: analysis of 168 necropsy cases. Am J Cardiol 1989 64 : 909 20.
2. Darke S., Kaye S., Duflou J. Systemic disease among cases of fatal opioid toxicity. Addiction 2006 101 : 1299 305.
3. Darke S., Kaye S., Duflou J. Comparative cardiac pathology among deaths due to cocaine toxicity, opioid toxicity and non-drug-related causes. Addiction 2006 101 : 1771 7.
4. Passarino G., Ciccone G., Siragusa R., Tappero P., Mollo F. Histopathological findings in 851 autopsies of drug addicts, with toxicologic and virologic correlations. Am J Forens Med Pathol 2005 26 : 106 16.
5. Kringsholm B., Christoffersen P. Lung and heart pathology in fatal drug addiction. A consecutive autopsy study. Forensic Sci Int 1987 34 : 39 51.
6. Maremmani I., Pacini M., Cesaroni C., Lovrecic M., Perugi G., Tagliamonte A. Q. Tc interval prolongation in patients on long-term methadone maintenance therapy. Eur Addict Res 2005 11 : 44 9.
7. Peles E., Bodner G., Kreek M. J., Rados V., Adelson M. Corrected-QT intervals as related to methadone dose and serum level in methadone maintenance treatment (MMT) patients: a cross-sectional study. Addiction 2007 102 : 289 300.
8. Ehret G. B., Voide C., Gex-Fabry M., Chabert J., Shah D., Broers B. et al. Drug-induced long QT syndrome in injection drug users receiving methadone: high frequency in hospitalized patients and risk factors. Arch Intern Med 2006 166 : 1280 7.
9. Sutherland S. E., Gazes P. C., Keil J. E., Gilbert G. E., Knapp R. G. Electrocardiographic abnormalities and 30-year mortality among white and black men of the Charleston Heart Study. Circulation 1993 88 : 2685 92.
10. Barrett P. A., Peter C. T., Swan H. J., Singh B. N., Mandel W. J. The frequency and prognostic significance of electrocardiographic abnormalities in clinically normal individuals. Prog Cardiovasc Dis 1981 23 : 299 319.
11. Greenland P., Xie X., Liu K., Colangelo L., Liao Y., Daviglus M. L. et al. Impact of minor electrocardiographic ST-segment and/or T-wave abnormalities on cardiovascular mortality during long-term follow-up. Am J Cardiol 2003 91 : 1068 74.
12. Daviglus M. L., Liao Y., Greenland P., Dyer A. R., Liu K., Xie X. et al. Association of nonspecific minor ST-T abnormalities with cardiovascular mortality: the Chicago Western Electric Study. JAMA 1999 281 : 530 6.
13. De Bacquer D., De Backer G., Kornitzer M. Prevalences of ECG findings in large population based samples of men and women. Heart 2000 84 : 625 33.
14. Larsen C. T., Dahlin J., Blackburn H., Scharling H., Appleyard M., Sigurd B. et al. Prevalence and prognosis of electrocardiographic left ventricular hypertrophy, ST segment depression and negative T-wave; the Copenhagen City Heart Study. Eur Heart J 2002 23 : 315 24.
15. Elming H., Holm E., Jun L., Torp-Pedersen C., Kober L., Kircshoff M. et al. The prognostic value of the QT interval and QT interval dispersion in all-cause and cardiac mortality and morbidity in a population of Danish citizens. Eur Heart J 1998 19 : 1391 400.
16. Okin P. M., Devereux R. B., Howard B. V., Fabsitz R. R., Lee E. T., Welty T. K. Assessment of QT interval and QT dispersion for prediction of all-cause and cardiovascular mortality in American Indians: the Strong Heart study. Circulation 2000 101 : 61 6.
17. Body Mass Index. Available at: (accessed 13 November 2007).
18. Finsterer J., Stöllberger C., Köcher K., Mamoli B. ECG abnormalities in myopathies, coronary heart disease and controls. Herz 1997 22 : 277 82.
19. Chen J. P. Methamphetamine-associated acute myocardial infarction and cardiogenic shock with normal coronary arteries: refractory global coronary microvascular spasm. J Invasive Cardiol 2007 19 : E89 92.
20. Sidney S. Cardiovascular consequences of marijuana use. J Clin Pharmacol 2002 42 : S64 70.
21. Agelink M. W., Majewski T. B., Andrich J., Mueck-Weymann M. Short-term effects of intravenous benzodiazepines on autonomic neurocardiac regulation in humans: a comparison between midazolam, diazepam, and lorazepam. Crit Care Med 2002 30 : 997 1006.
22. Starcevic B., Sicaja M. Dual intoxication with diazepam and amphetamine: this drug interaction probably potentiates myocardial ischemia. Med Hypoth 2007 69 : 377 80.
23. Bauman J. L., DiDomenico R. J. Cocaine-induced channelopathies: emerging evidence on the multiple mechanisms of sudden death. J Cardiovasc Pharmacol Ther 2002 7 : 195 202.
24. Sugita S., Takada K., Hayano J. Influence of body composition on electrocardiographic identification of left ventricular hypertrophy in adolescents. Cardiology 1999 91 : 127 33.
25. Ward S., Heyneman L. E., Reittner P., Kazerooni E. A., Godwin J. D., Müller N. L. Talcosis associated with IV abuse of oral medications: CT findings. Am J Roentgenol 2000 174 : 789 93.
26. Frontera J. A., Gradon J. D. Right-side endocarditis in injection drug users: review of proposed mechanisms of pathogenesis. Clin Infect Dis 2000 30 : 374 79.
27. Carozza A., De Santo L. S., Romano G., Della Corte A., Ursomando F., Scardone M. et al. Infective endocarditis in intravenous drug abusers: patterns of presentation and long-term outcomes of surgical treatment. J Heart Valve Dis 2006 15 : 125 31.
28. Kringsholm B., Christoffersen P. Lymph-node and thymus pathology in fatal drug addiction. Forensic Sci Int 1987 34 : 245 54.
29. Stöllberger C., Huber J. O., Finsterer J. Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol 2005 20 : 243 51.