메뉴 건너뛰기




Volumn 132, Issue 11, 2008, Pages 1767-1773

Histopathologic and clinical features of medullary microcarcinoma and C-cell hyperplasia in prophylactic thyroidectomies for medullary carcinoma: A study of 42 cases

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; CALCITONIN; EOSIN; HEMATOXYLIN;

EID: 55549137395     PISSN: 00039985     EISSN: 15432165     Source Type: Journal    
DOI: 10.1043/1543-2165-132.11.1767     Document Type: Article
Times cited : (47)

References (41)
  • 1
    • 33845399067 scopus 로고    scopus 로고
    • Pathology and genetics of thyroid carcinoma
    • DeLellis R. Pathology and genetics of thyroid carcinoma. J Surg Oncol. 2006;94:662-669.
    • (2006) J Surg Oncol , vol.94 , pp. 662-669
    • DeLellis, R.1
  • 2
    • 24944531368 scopus 로고    scopus 로고
    • Prophylactic thyroidectomy in multiple endocrine neoplasia type 2A
    • Skinner MA, Moley JA, Dilley WG, et al. Prophylactic thyroidectomy in multiple endocrine neoplasia type 2A. N Engl J Med. 2005;353:1105-1113.
    • (2005) N Engl J Med , vol.353 , pp. 1105-1113
    • Skinner, M.A.1    Moley, J.A.2    Dilley, W.G.3
  • 3
    • 33750509391 scopus 로고    scopus 로고
    • Prognosis of medullary thyroid carcinoma: Demographic, clinical, pathologic predictors of survival in 1252 cases
    • Roman S, Lin R, Sosa J. Prognosis of medullary thyroid carcinoma: demographic, clinical, pathologic predictors of survival in 1252 cases. Cancer. 2006;107:2134-2142.
    • (2006) Cancer , vol.107 , pp. 2134-2142
    • Roman, S.1    Lin, R.2    Sosa, J.3
  • 4
    • 14444272505 scopus 로고    scopus 로고
    • Prognostic factors for survival and for biochemical cure in medullary thyroid carcinoma: Results in 899 patients
    • Modigliani E, Cohen R, Campos JM, et al. Prognostic factors for survival and for biochemical cure in medullary thyroid carcinoma: results in 899 patients. Clin Endocrinol. 1998;48:265-273.
    • (1998) Clin Endocrinol , vol.48 , pp. 265-273
    • Modigliani, E.1    Cohen, R.2    Campos, J.M.3
  • 5
    • 0034815430 scopus 로고    scopus 로고
    • Sporadic versus familial medullary thyroid microcarcinoma: A histopathologic study of 50 consecutive patients
    • Kaserer K, Scheuba C, Neuhold N, et al. Sporadic versus familial medullary thyroid microcarcinoma: a histopathologic study of 50 consecutive patients. Am J Surg Pathol. 2001;25:1245-1251.
    • (2001) Am J Surg Pathol , vol.25 , pp. 1245-1251
    • Kaserer, K.1    Scheuba, C.2    Neuhold, N.3
  • 6
    • 0031814805 scopus 로고    scopus 로고
    • C-cell hyperplasia and medullary thyroid carcinoma in patients routinely screened for serum calcitonin
    • Kaserer K, Scheuba C, Neuhold N, et al. C-cell hyperplasia and medullary thyroid carcinoma in patients routinely screened for serum calcitonin. Am J Surg Pathol. 1998;22:722-728.
    • (1998) Am J Surg Pathol , vol.22 , pp. 722-728
    • Kaserer, K.1    Scheuba, C.2    Neuhold, N.3
  • 7
    • 10744228150 scopus 로고    scopus 로고
    • C-cell hyperplasia and medullary thyroid carcinoma: Clinicopathological and genetic correlations in 66 consecutive patients
    • Guyétant S, Josselin N, Savagner F, et al. C-cell hyperplasia and medullary thyroid carcinoma: clinicopathological and genetic correlations in 66 consecutive patients. Mod Pathol. 2003;16:756-763.
    • (2003) Mod Pathol , vol.16 , pp. 756-763
    • Guyétant, S.1    Josselin, N.2    Savagner, F.3
  • 8
    • 0034081895 scopus 로고    scopus 로고
    • Inherited medullary microcarcinoma of the thyroid: A study of 11 cases
    • Krueger JE, Maitra A, Albores-Saavedra J. Inherited medullary microcarcinoma of the thyroid: a study of 11 cases. Am J Surg Pathol. 2000;24:853-858.
    • (2000) Am J Surg Pathol , vol.24 , pp. 853-858
    • Krueger, J.E.1    Maitra, A.2    Albores-Saavedra, J.3
  • 9
    • 0028174024 scopus 로고
    • A mutation in the RET protooncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma
    • Hofstra RM, Landsvater RM, Ceccherini I, et al. A mutation in the RET protooncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma. Nature. 1994;367:375-376.
    • (1994) Nature , vol.367 , pp. 375-376
    • Hofstra, R.M.1    Landsvater, R.M.2    Ceccherini, I.3
  • 10
    • 4143126470 scopus 로고    scopus 로고
    • Frequency of RET protooncogene mutations in patients with normal and with moderately elevated pentagastrin-stimulated serum concentrations of calcitonin
    • Vierhapper H, Bieglmayer C, Heinze G, et al. Frequency of RET protooncogene mutations in patients with normal and with moderately elevated pentagastrin-stimulated serum concentrations of calcitonin. Thyroid. 2004;14:580-583.
    • (2004) Thyroid , vol.14 , pp. 580-583
    • Vierhapper, H.1    Bieglmayer, C.2    Heinze, G.3
  • 11
    • 0029848352 scopus 로고    scopus 로고
    • Distinction between sporadic and hereditary medullary thyroid carcinoma (MTC) by mutation analysis of the RET proto-oncogene
    • Fink M, Weinhüsel A, Niederle B, Haas OA. Distinction between sporadic and hereditary medullary thyroid carcinoma (MTC) by mutation analysis of the RET proto-oncogene. Int J Cancer. 1996;22:69:312-316.
    • (1996) Int J Cancer , vol.22 , Issue.69 , pp. 312-316
    • Fink, M.1    Weinhüsel, A.2    Niederle, B.3    Haas, O.A.4
  • 12
    • 0030063766 scopus 로고    scopus 로고
    • Physiologic versus neoplastic C-cell hyperplasia of the thyroid
    • Perry A, Molberg K, Albores-Saavedra J. Physiologic versus neoplastic C-cell hyperplasia of the thyroid. Cancer. 1996;77:750-756.
    • (1996) Cancer , vol.77 , pp. 750-756
    • Perry, A.1    Molberg, K.2    Albores-Saavedra, J.3
  • 14
    • 13044269061 scopus 로고    scopus 로고
    • Medullary thyroid microcarcinoma: A clinicopathologic retrospective study of 38 patients with no prior familial disease
    • Guyétant S, Dupre F, Bigorgne JC, et al. Medullary thyroid microcarcinoma: a clinicopathologic retrospective study of 38 patients with no prior familial disease. Hum Pathol. 1999;30:957-963.
    • (1999) Hum Pathol , vol.30 , pp. 957-963
    • Guyétant, S.1    Dupre, F.2    Bigorgne, J.C.3
  • 16
    • 12844251289 scopus 로고    scopus 로고
    • Familial multiple endocrine neoplasia: The first 100 years
    • Carney JA. Familial multiple endocrine neoplasia: the first 100 years. Am J Surg Pathol. 2005;29:254-274.
    • (2005) Am J Surg Pathol , vol.29 , pp. 254-274
    • Carney, J.A.1
  • 17
    • 0027178469 scopus 로고
    • Occult carcinoma of the thyroid: A systematic autopsy study from Spain of two series performed with two different methods
    • Martinez-Tello FJ, Martinez-Cabruja R, Fernandez-Martin J, et al. Occult carcinoma of the thyroid: a systematic autopsy study from Spain of two series performed with two different methods. Cancer. 1993;71:4022-4029.
    • (1993) Cancer , vol.71 , pp. 4022-4029
    • Martinez-Tello, F.J.1    Martinez-Cabruja, R.2    Fernandez-Martin, J.3
  • 18
    • 30844451553 scopus 로고    scopus 로고
    • Presymptomatic thyroidectomy in multiple endocrine neoplasia 2a
    • Heizmann O, Haecker FM, Zumsteg U, et al. Presymptomatic thyroidectomy in multiple endocrine neoplasia 2a. J Cancer Surg. 2006;32:98-102.
    • (2006) J Cancer Surg , vol.32 , pp. 98-102
    • Heizmann, O.1    Haecker, F.M.2    Zumsteg, U.3
  • 19
    • 0031668013 scopus 로고    scopus 로고
    • Primary hereditary medullary thyroid carcinoma - C-cell morphology and correlation with preoperative calcitonin levels
    • Hinze R, Holzhausen HJ, Gimm O, et al. Primary hereditary medullary thyroid carcinoma - C-cell morphology and correlation with preoperative calcitonin levels. Virchows Arch. 1998;433:203-208.
    • (1998) Virchows Arch , vol.433 , pp. 203-208
    • Hinze, R.1    Holzhausen, H.J.2    Gimm, O.3
  • 20
    • 0141940150 scopus 로고    scopus 로고
    • Early malignant progression of hereditary medullary thyroid cancer
    • Machens A, Niccoli-Sire P, Hogel J, et al. Early malignant progression of hereditary medullary thyroid cancer. N Engl J Med. 2003;349:1517-1525.
    • (2003) N Engl J Med , vol.349 , pp. 1517-1525
    • Machens, A.1    Niccoli-Sire, P.2    Hogel, J.3
  • 21
    • 0032756813 scopus 로고    scopus 로고
    • Is medullary thyroid cancer predictable?: A prospective study of 86 patients with abnormal pentagastrin tests
    • Scheuba C, Kaserer K, Weinhausl A, et al. Is medullary thyroid cancer predictable?: a prospective study of 86 patients with abnormal pentagastrin tests. Surgery. 1999;126:1089-1096.
    • (1999) Surgery , vol.126 , pp. 1089-1096
    • Scheuba, C.1    Kaserer, K.2    Weinhausl, A.3
  • 22
    • 29244451056 scopus 로고    scopus 로고
    • Early diagnosis and curative therapy of medullary thyroid carcinoma by routine measurement of serum calcitonin in patients with thyroid disorders
    • Vierhapper H, Niederle B, Bieglmayer C, et al. Early diagnosis and curative therapy of medullary thyroid carcinoma by routine measurement of serum calcitonin in patients with thyroid disorders. Thyroid. 2005;15:1267-1272.
    • (2005) Thyroid , vol.15 , pp. 1267-1272
    • Vierhapper, H.1    Niederle, B.2    Bieglmayer, C.3
  • 23
    • 33846537919 scopus 로고    scopus 로고
    • Familial medullary carcinoma prevention, risk evaluation, and RET in children of families with MEN2
    • Moore SW, Appfelstaedt J, Zaahl MG. Familial medullary carcinoma prevention, risk evaluation, and RET in children of families with MEN2. J Pediatr Surg. 2007;42:326-332.
    • (2007) J Pediatr Surg , vol.42 , pp. 326-332
    • Moore, S.W.1    Appfelstaedt, J.2    Zaahl, M.G.3
  • 24
    • 0000180356 scopus 로고    scopus 로고
    • Tumors of the thyroid and parathyroid glands
    • Fletcher CDM, ed, 3rd ed. London, England: Churchill Livingstone;
    • Chan JKC. Tumors of the thyroid and parathyroid glands. In: Fletcher CDM, ed. Diagnostic Histopathology of Tumors. 3rd ed. London, England: Churchill Livingstone; 2007:997-1097.
    • (2007) Diagnostic Histopathology of Tumors , pp. 997-1097
    • Chan, J.K.C.1
  • 25
    • 33845507104 scopus 로고    scopus 로고
    • Mutation analysis of the RET proto-oncogene and early thyroidectomy: Results of a Portuguese cancer centre
    • Bugalho JM, Domingues R, Santos JR, et al. Mutation analysis of the RET proto-oncogene and early thyroidectomy: results of a Portuguese cancer centre. Surgery. 2007;141:90-95.
    • (2007) Surgery , vol.141 , pp. 90-95
    • Bugalho, J.M.1    Domingues, R.2    Santos, J.R.3
  • 26
    • 85193609047 scopus 로고    scopus 로고
    • de Groot JW, Links TP, Plukker J, et al. RET as a diagnostic and therapeutic target in sporadic and hereditary endocrine tumors. Endocr Rev. 2006;27:535-550.
    • de Groot JW, Links TP, Plukker J, et al. RET as a diagnostic and therapeutic target in sporadic and hereditary endocrine tumors. Endocr Rev. 2006;27:535-550.
  • 27
    • 23644441629 scopus 로고    scopus 로고
    • Penetrance and clinical manifestations of non-hotspot germline RET mutation, C630R, in a family with medullary thyroid carcinoma
    • Dourisboure RJ, Belli S, Domenichini E, et al. Penetrance and clinical manifestations of non-hotspot germline RET mutation, C630R, in a family with medullary thyroid carcinoma. Thyroid. 2005;15:668-671.
    • (2005) Thyroid , vol.15 , pp. 668-671
    • Dourisboure, R.J.1    Belli, S.2    Domenichini, E.3
  • 28
    • 33845505283 scopus 로고    scopus 로고
    • Medullary thyroid cancer: The importance of RET testing
    • Evans DB, Shapiro SE, Cote GJ. Medullary thyroid cancer: the importance of RET testing. Surgery. 2007;141:96-99.
    • (2007) Surgery , vol.141 , pp. 96-99
    • Evans, D.B.1    Shapiro, S.E.2    Cote, G.J.3
  • 29
    • 16644386128 scopus 로고    scopus 로고
    • Timing and extent of surgery in patients with familial medullary thyroid carcinoma/multiple endocrine neoplasia 2A-related RET mutations not affecting codon 634
    • Gimm O, Ukkat J, Niederle BE, et al. Timing and extent of surgery in patients with familial medullary thyroid carcinoma/multiple endocrine neoplasia 2A-related RET mutations not affecting codon 634. World J Surg. 2004;28:1312-1316.
    • (2004) World J Surg , vol.28 , pp. 1312-1316
    • Gimm, O.1    Ukkat, J.2    Niederle, B.E.3
  • 30
    • 33745168935 scopus 로고    scopus 로고
    • New era: Prophylactic surgery for patients with multiple endocrine neoplasia 2A
    • Gosnell JE, Sywak MS, Sidhu SB, et al. New era: prophylactic surgery for patients with multiple endocrine neoplasia 2A. ANZ J Surg. 2006;76:586-590.
    • (2006) ANZ J Surg , vol.76 , pp. 586-590
    • Gosnell, J.E.1    Sywak, M.S.2    Sidhu, S.B.3
  • 31
    • 8544224970 scopus 로고    scopus 로고
    • Novel germline RET protooncogene mutations associated with medullary thyroid carcinoma (MTC): Mutation analysis in Japanese patients with MTC
    • Kitamura Y, Goodfellow PJ, Shimizu K, et al. Novel germline RET protooncogene mutations associated with medullary thyroid carcinoma (MTC): mutation analysis in Japanese patients with MTC. Oncogene. 1997;14:3103-3106.
    • (1997) Oncogene , vol.14 , pp. 3103-3106
    • Kitamura, Y.1    Goodfellow, P.J.2    Shimizu, K.3
  • 32
    • 28844445630 scopus 로고    scopus 로고
    • Experience of prophylactic thyroidectomy in multiple endocrine neoplasia type 2A kindreds with RET codon 804 mutations
    • Learoyd DL, Gosnell JE, Elston MS, et al. Experience of prophylactic thyroidectomy in multiple endocrine neoplasia type 2A kindreds with RET codon 804 mutations. Clin Endocrinol. 2005;63:636-641.
    • (2005) Clin Endocrinol , vol.63 , pp. 636-641
    • Learoyd, D.L.1    Gosnell, J.E.2    Elston, M.S.3
  • 33
    • 0141481958 scopus 로고    scopus 로고
    • Malignant progression from C-cell hyperplasia to medullary thyroid carcinoma in 167 carriers of RET germline mutations
    • Machens A, Holzhausen HJ, Thanh NP, et al. Malignant progression from C-cell hyperplasia to medullary thyroid carcinoma in 167 carriers of RET germline mutations. Surgery. 2003;134:425-431.
    • (2003) Surgery , vol.134 , pp. 425-431
    • Machens, A.1    Holzhausen, H.J.2    Thanh, N.P.3
  • 34
    • 33847681936 scopus 로고    scopus 로고
    • RET proto-oncogene in Sardinia: V804M is the most frequent mutation and may be associated with FMTC/MEN-2A phenotype
    • Pinna G, Orgiana G, Riola A, et al. RET proto-oncogene in Sardinia: V804M is the most frequent mutation and may be associated with FMTC/MEN-2A phenotype. Thyroid. 2007;17:101-104.
    • (2007) Thyroid , vol.17 , pp. 101-104
    • Pinna, G.1    Orgiana, G.2    Riola, A.3
  • 35
    • 0037080134 scopus 로고    scopus 로고
    • Very early detection of RET protooncogene mutation is crucial for preventive thyroidectomy in multiple endocrine neoplasia type 2 children: Presence of C-cell malignant disease in asymptomatic carriers
    • Sanso GE, Domene HM, Garcia R, et al. Very early detection of RET protooncogene mutation is crucial for preventive thyroidectomy in multiple endocrine neoplasia type 2 children: presence of C-cell malignant disease in asymptomatic carriers. Cancer. 2002;94:323-330.
    • (2002) Cancer , vol.94 , pp. 323-330
    • Sanso, G.E.1    Domene, H.M.2    Garcia, R.3
  • 36
    • 0037313426 scopus 로고    scopus 로고
    • Review of multiple endocrine neoplasia type 2A in children: Therapeutic results of early thyroidectomy and prognostic value of codon analysis
    • Szinnai G, Meier C, Komminoth P, et al. Review of multiple endocrine neoplasia type 2A in children: therapeutic results of early thyroidectomy and prognostic value of codon analysis. Pediatrics. 2003;111:132-139.
    • (2003) Pediatrics , vol.111 , pp. 132-139
    • Szinnai, G.1    Meier, C.2    Komminoth, P.3
  • 37
    • 0028061726 scopus 로고
    • Predictive DNA testing and prophylactic thyroidectomy in patients at risk for multiple endocrine neoplasia type 2A
    • Wells SA, Chi DD, Toshima K, et al. Predictive DNA testing and prophylactic thyroidectomy in patients at risk for multiple endocrine neoplasia type 2A. Ann Surg. 1994;237-250.
    • (1994) Ann Surg , pp. 237-250
    • Wells, S.A.1    Chi, D.D.2    Toshima, K.3
  • 38
    • 0031014504 scopus 로고    scopus 로고
    • Long term follow-up of patients with medullary carcinoma of the thyroid
    • Bergholm U, Bergström R, Ekbom A. Long term follow-up of patients with medullary carcinoma of the thyroid. Cancer. 1997;79:132-138.
    • (1997) Cancer , vol.79 , pp. 132-138
    • Bergholm, U.1    Bergström, R.2    Ekbom, A.3
  • 39
    • 10044248977 scopus 로고    scopus 로고
    • Medullary and papillary tumors are frequently associated within the same thyroid gland without evidence of reciprocal influence in their biologic behavior
    • Biscolla PR, Ugolini C, Sculli M, et al. Medullary and papillary tumors are frequently associated within the same thyroid gland without evidence of reciprocal influence in their biologic behavior. Thyroid. 2004;14:946-952.
    • (2004) Thyroid , vol.14 , pp. 946-952
    • Biscolla, P.R.1    Ugolini, C.2    Sculli, M.3
  • 40
    • 3242769786 scopus 로고    scopus 로고
    • The oncogenic activity of RET point mutants for follicular thyroid cells may account for the occurrence of papillary thyroid carcinoma in patients affected by familial medullary thyroid carcinoma
    • Melillo RM, Cirafici AM, De Falco V, et al. The oncogenic activity of RET point mutants for follicular thyroid cells may account for the occurrence of papillary thyroid carcinoma in patients affected by familial medullary thyroid carcinoma. Am J Pathol. 2004;165:511-521.
    • (2004) Am J Pathol , vol.165 , pp. 511-521
    • Melillo, R.M.1    Cirafici, A.M.2    De Falco, V.3
  • 41
    • 21244461133 scopus 로고    scopus 로고
    • Medullary and papillary thyroid carcinoma of the the thyroid gland occurring as a collision tumour: Report of three cases with molecular analysis and review of the literature
    • Rossi S, Fugazzola L, De Pasquale L, et al. Medullary and papillary thyroid carcinoma of the the thyroid gland occurring as a collision tumour: report of three cases with molecular analysis and review of the literature. Endocr Relat Cancer. 2005;12:281-289.
    • (2005) Endocr Relat Cancer , vol.12 , pp. 281-289
    • Rossi, S.1    Fugazzola, L.2    De Pasquale, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.