A new triterpene and new sesquiterpenes from the roots of Ligularia sagitta

Helvetica Chimica Acta

Volumn 91, Issue 9, 2008, Pages 1717-1727

  Li, Ping Lin ^a   Jia, Zhong Jian ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; NUCLEAR MAGNETIC RESONANCE; SPECTRUM ANALYZERS;

OLEANANE; SAGITTA; SESQUITERPENES; SPECTRAL ANALYSES; TRITERPENE; TUMOR CELL LINES;

OLEFINS;

(7BETA,16BETA) 3 OXOOLEAN 12 ENE 7,16,28 TRIYLTRIACETATE; 1,2,3,5,6,7,8,8 OCTAHYDRO 5 HYDROXY 8,8 DIMETHYL 3 OXONAPHTHALEN 2 YLACETATE; 2,4,4A,5,6,7,8,8 OCTAHYDRO 8 HYDROXY 3,4,5 TRIMETHYL 2 OXONAPHTHO[2,3 B]FURAN 4,8 DIYLDIACETATE; 4,4,5,6,7,8,8,9 OCTAHYDRO 8,8 DIHYDROXY 3,4,5 TRIMETHYLNAPHTHO[2,3 B]FURAN 4 YL 2 (HYDROXYMETHYL)PROP 2 ENOATE; 5 (ACETYLOXY) 3,5,6,7,8,8 HEXAHYDRO 8,8 DIMETHYL 3 OXONAPHTHALEN 2(1H)YLIDINE]ETHYLACETATE; 5,6,7,8 TETRAHYDRO 3,8 DIHYDROXY 4,5 DIMETHYLNAPHTHALEN 2 (4H)ONE; 5,6,7,8 TETRAHYDRO 8 HYDROXY 3 (1 HYDROXYPROPAN 2 YL) 4,5 DIMETHYLNAPHTHALEN 2 (4H)ONE; 6 ACETYL 1,2,3,4,4,5 HEXAHYDRO 4,4 DIMETHYLNAPHTHALENE 1,7 DIYLDIACETATE; SESQUITERPENE DERIVATIVE; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG; VINCRISTINE SULFATE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; FEMALE; HEPATOMA CELL; HETERONUCLEAR MULTIPLE BOND CORRELATION; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; LEUKEMIA CELL; LIGULARIA SAGITTA; MASS SPECTROMETRY; MEDICINAL PLANT; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PLANT ROOT; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA;

EID: 55549137046     PISSN: 0018019X     EISSN: None     Source Type: Journal    
DOI: 10.1002/hlca.200890188     Document Type: Article

References (32)

1. K. C. How, 'A Dictionary of the Families and Genera of Chinese Seed Plants', 2nd edn., Science Press, Beijing, 1982, p. 276;
2. Jiangsu New Medicinal College, KA Dictionary of Traditional Chinese Drugs', Shanghai People's Press, Shanghai, 1977, p. 2305, 2348, and 1806;
3. L.-S. Chen, W.-Z. Song, Zhongcaoyao 1987, 18, 421.
4. K. Sugama, K. Hayashi, H. Mitsuhashi, Phytochemistry 1985, 24, 1531;
5. Y. Wang, H. M. Chen, Zhongguo Yaoxue Zazhi 1998, 33, 19;
6. L. H. Zalkow, J. A. Glinski, L. T. Gelbaum, T. J. Fleischmann, L. S. McGowan, M. M. Gordon, J. Med. Chem. 1985, 28, 687;
7. G. Lin, P. Rose, K. B. Chatson, E. M. Hawes, X. G. Zhao, Z. T. Wang, J. Nat. Prod. 2000, 63, 857.
8. a) Z. Jia, Y. Zhao, R. Tan, J. Nat. Prod. 1993, 56, 494;
9. b) Y. Zhao, Z. Jia, Y. Li, Phytochemistry 1994, 37, 1149;
10. c) Y. Zhao, H. Peng, Z. Jia, J. Nat. Prod. 1994, 57, 1626;
11. d) Z. Jia, Y. Zhao, J. Nat. Prod. 1994, 57, 146;
12. e) K. Gao, L. Yang, Z. Jia, Planta Med. 1997, 63, 461;
13. f) B. Ma, K. Gao, Y.-P. Shi, Z.-J. Jia, Phytochemistry 1997, 46, 915;
14. g) W. S. Wang, K. Gao, L. Yang, Z. J. Jia, Planta Med. 2000, 66, 189;
15. h) Y. F. Han, K. Gao, Z. J. Jia, Chem. Lett. 2005, 34, 892;
16. i) F.-L. Yan, A.-X. Wang, Z.-J. Jia, Pharmazie 2005, 60, 155;
17. j) X. Gao, C.-J. Lin, W.-D. Xie, T. Shen, Z.-J. Jia, Helv. Chim. Acta 2006, 89, 1387;
18. k) Z.-X. Zhang, C.-J. Lin, P.-L. Li, Z.-J. Jia, Planta Med. 2007, 73, 585.
19. Z. Liu, H. Chen, Z. Jia, N. K. Dalley, X. Kou, D. Li, N. L. Owen, D. M. Grant, Phytochemistry 1995, 40, 1191;
20. H. Chen, Z. Jia, Y. Li, Phytochemistry 1992, 31, 2146;
21. X.-Q. Li, K. Gao, Z.-J. Jia, Planta Med. 2003, 69, 356.
22. W. S. Wang, K. Gao, C. M. Wang, Z. J. Jia, Pharmazie 2003, 58, 148.
23. Y. Moriyama, T. Takahashi, Bull. Chem. Soc. Jpn. 1976, 49, 3196.
24. P.-L. Li, C.-M. Wang, Z.-X. Zhang, Z.-J. Jia, Tetrahedron 2007, 63, 12665.
25. S. Zhang, G. Zhao, R. Li, G. Lin, Phytochemistry 1998, 48, 519.
26. F.-J. Meng, H. Zhao, W.-D. Xie, R.-J. Zhao, P.-X. Lai, Y.-X. Zhou, Y.-L. Miao, Helv. Chim. Acta 2007, 90, 2196;
27. J.-C. Liao, Q.-X. Zhu, X.-P. Yang, Z.-J. Jia, J. Chin. Chem. Soc. 2002, 49, 129.
28. Y. Zhao, Z. J. Jia, H. R. Peng, J. Nat. Prod. 1995, 58, 1358.
29. a) H. Nagano, T. Takahashi, Bull. Chem. Soc. Jpn. 1978, 51, 3335;
30. b) T. Sato, Y. Moriyama, H. Nagano, Y. Tanahashi, T. Takahashi, Bull. Chem. Soc. Jpn. 1975, 48, 112.
31. Q. Wang, Q. Mu, M. Shibano, S. L. Morris-Natschke, K.-H. Lee, D.-F. Chen, J. Nat. Prod. 2007, 70, 1259.
32. P. Skehan, R. Storeng, D. Scudiero, A. Monks, J. McMohan, D. Vistica, J. Warren, J. Bokesh, S. Kenney, M. R. Boyd, J. Natl. Cancer Inst. 1990, 82, 1107.