GABAA receptors in the central nucleus of amygdala (CeA) affect on pain modulation

Brain Research

Volumn 1241, Issue , 2008, Pages 36-41

  Hasanein, Parisa ^a   Mirazi, Naser ^a   Javanmardi, Kazem ^b  

^a BU ALI SINA UNIVERSITY   (Iran)

^b FASA UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Amygdala; Antinociception; Bicuculline; GABAA; Muscimol; Rat

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BICUCULLINE; MUSCIMOL; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT;

4 AMINOBUTYRIC ACID RELEASE; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HYPERALGESIA; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; TAIL FLICK TEST; ANIMAL; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; MALE; METABOLISM; METHODOLOGY; MICROINJECTION; NERVE CELL INHIBITION; NOCICEPTIVE RECEPTOR; PAIN; PAIN ASSESSMENT; PAIN THRESHOLD; PATHOPHYSIOLOGY; PHYSIOLOGY; REACTION TIME; SYNAPTIC TRANSMISSION; WISTAR RAT;

RATTUS;

AMYGDALA; ANIMALS; BICUCULLINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GABA AGONISTS; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; MALE; MICROINJECTIONS; MUSCIMOL; NEURAL INHIBITION; NOCICEPTORS; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; RATS; RATS, WISTAR; REACTION TIME; RECEPTORS, GABA-A; SYNAPTIC TRANSMISSION;

EID: 55549119217     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.09.041     Document Type: Article

References (31)

1. Bernard J.F., Alden M., and Besson J.M. The organization of the efferent projections from the pontine parabrachial area to the amygdaloid complex: a Phaseolus vulgaris leucoagglutinin (PHA-L) study in the rat. J. Comp. Neurol. 329 (1993) 201-229
2. Bester H., Chapman V., Besson J.M., and Bernard J.F. Physiological properties of the lamina I spinoparabrachial neurons in the rat. J. Neurophysiol. 83 (2000) 2239-2259
3. da Motta P.G., Veiga A.P., Francischi J.N., and Tatsuo M.A. Evidence for participation of GABA(A) receptors in a rat model of secondary hyperalgesia. Eur. J. Pharmacol. 483 (2004) 233-239
4. Delaney A.J., and Sah P. Pathway-specific targeting of GABA (A) receptor subtypes to somatic and dendritic synapses in the central amygdala. J. Neurophysiol. 86 (2001) 717-723
5. Finnegan T.F., Chen S.R., and Pan H.L. Effect of the {mu} opioid on excitatory and inhibitory synaptic inputs to periaqueductal gray-projecting neurons in the amygdala. J. Pharmacol. Exp. Ther. 312 (2005) 441-448
6. Gilbert A.K., and Franklin K.B. GABAergic modulation of descending inhibitory systems from the rostral ventromedial medulla (RVM) dose-response analysis of nociception and neurological deficits. Pain 90 (2001) 25-36
7. Hammond D.L. Role of spinal GABA in acute and persistent nociception. Reg. Anesth. Pain. Med. 26 (2001) 551-557
8. Heinricher M.M., and Kaplan H.J. GABA-mediated inhibition in rostral ventromedial medulla: role in nociceptive modulation in the lightly anesthetized rat. Pain 47 (1991) 105-113
9. Heinricher M.M., and Tortorici V. Interference with GABA transmission in the rostral ventromedial medulla: disinhibition of off-cells as a central mechanism in nociceptive modulation. Neuroscience 63 (1994) 533-546
10. Jia H., Xie Y.F., Xiao D.Q., and Tang J.S. Involvement of GABAergic modulation of the nucleus submedius (Sm) morphine-induced antinociception. Pain 108 (2004) 28-35
11. Mahmoudi M., and Zarrindast M.R. Effect of intracerebroventricular injection of GABA receptor agents on morphine-induced antinociception in the formalin test. J. Psychopharmacol. 16 (2002) 85-91
12. Manning B.H., and Mayer D.J. The central nucleus of the amygdala contributes to the production of morphine antinociception in the rat tail-flick test. J. Neurosci. 15 (1995) 8199-8213
13. Manning B.H., and Mayer D.J. The central nucleus of the amygdala contributes to the production of morphine antinociception in the formalin test. Pain 63 (1995) 141-152
14. Manning B.H. A lateralized deficit in morphine antinociception after unilateral inactivation of the central amygdala. J. Neurosci. 18 (1998) 9453-9470
15. Marowsky A., Fritschy J.M., and Vogt K.E. Functional mapping of GABA A receptor subtypes in the amygdala. Eur. J. Neurosci. 20 (2004) 1281-1289
16. McDonald A.J., and Mascagni F. Parvalbumin-containing interneurons in the basolateral amygdale express high levels of the α1 subunit of the GABA (A) receptor. J. Comp. Neurol. 473 (2004) 137-146
17. McGaraughty S., Farr D.A., and Heinricher M.M. Lesions of the periaqueductal gray disrupt input to the rostral ventromedial medulla following microinjections of morphine into the medial or basolateral nuclei of the amygdala. Brain Res. 1009 (2004) 223-227
18. McGowan M.K., and Hammond D.L. Antinociception produced by microinjection of l-glutamate into the ventromedial medulla of the rat: mediation by spinal GABA (A) receptors. Brain Res. 620 (1993) 86-96
19. Millan M.J. The induction of pain: an integrative review. Prog. Neurobiol. 57 (1999) 1-164
20. Millan M.J. Descending control of pain. Prog. Neurobiol. 66 (2002) 355-474
21. Moreau J.L., and Fields H.L. Evidence for GABA involvement in midbrain control of medullary neurons that modulate nociceptive transmission. Brain Res. 397 (1986) 37-46
22. Neugebauer V., Li W., Bird G.C., and Han J.S. The amygdala and persistent pain. Neuroscientist 10 (2004) 221-234
23. Neugebauer V., Li W., Bird G.C., Bhave G., and Gereau R.W.T. Synaptic plasticity in the amygdala in a model of arthritic pain: differential roles of metabotropic glutamate receptors 1 and 5. J. Neurosci. 23 (2003) 52-63
24. Ortiz J.P., Heinricher M.M., and Selden N.R. Noradrenergic agonist administration into the central nucleus of the amygdala increases the tail-flick latency in lightly anesthetized rats. Neuroscience 148 (2007) 737-743
25. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates (1986), Academic Press, New York
26. Qu C.L., Tang J.S., and Jia H. Involvement of GABAergic modulation of antinociception induced by morphine microinjected into the ventrolateral orbital cortex. Brain Res. 1073-1074 (2006) 281-289
27. Rea K., Roche M., and Finn D.P. Supraspinal modulation of pain by cannabinoids: the role of GABA and glutamate. Br. J. Pharmacol. 152 (2007) 633-648
28. Swanson L.W., and Petrovich G.D. What is the amygdala?. Trends. Neurosci. 21 (1998) 231-323
29. Vanegas H., and Schaible H.G. Descending control of persistent pain: inhibitory or facilitatory?. Brain Res. Rev. 46 (2004) 295-309
30. Xiao, D.Q., Zhu, J.X., Tang, J.S., Jia, H., 2005. GABAergic modulation mediates antinociception produced by serotonin applied into thalamic nucleus submedius of the rat. Brain Res. 28; 1057:161-167.
31. Zhu W., and Pan Z.Z. Synaptic properties and postsynaptic opioid effects in rat central amygdala neurons. Neuroscience 127 (2004) 871-879