Switching from methadone to a different opioid: What is the equianalgesic dose ratio?

Journal of Palliative Medicine

Volumn 11, Issue 8, 2008, Pages 1103-1108

  Walker, Paul W ^a   Palla, Shana ^a   Pei, Be Lian ^a   Kaur, Guddi ^a   Zhang, Karen ^a   Hanohano, Jeanine ^a   Munsell, Mark ^a   Bruera, Eduardo ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FENTANYL; HYDROMORPHONE; METHADONE; MORPHINE; OXYCODONE;

ADULT; ARTICLE; CANCER PAIN; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE CALCULATION; DRUG SUBSTITUTION; EVALUATION; FEMALE; HUMAN; MALE; MEDICAL RECORD REVIEW; RETROSPECTIVE STUDY;

ADULT; ANALGESICS, OPIOID; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; METHADONE; MIDDLE AGED; NEOPLASMS; PAIN, INTRACTABLE; RETROSPECTIVE STUDIES; THERAPEUTIC EQUIVALENCY;

EID: 55549104737     PISSN: 10966218     EISSN: None     Source Type: Journal    
DOI: 10.1089/jpm.2007.0285     Document Type: Article

References (19)

1. Moryl N, Santiago-Palma J, Kornick C, Derby S, Fischberg D, Payne R, Manfredi PL: Pitfalls of opioid rotation: Substituting another opioid for methadone in patients with cancer pain. Pain 2002;96:325-32 8.
2. Jacox A, Carr DB, Payne R, Berde CB, Breitbart W, Cain JM: Management of cancer pain. Clinical practice guidelines No. 9. AHCPR Publication No. 94-0592. Rockville, MD: Agency for Health Care Policy and Research, US Department of Health and Human Services, Public Health Service; 1994.
3. Bruera E, Pereira J, Watanabe S, Belzile M, Kuehn N, Hanson J: Opioid rotation in patients with cancer pain. A retrospective comparison of dose ratios between methadone, hydromorphone, and morphine. Cancer 1996;78:852-857.
4. Mercadante S: Opioid rotation for cancer pain: rationale and clinical aspects. Cancer 1999;86:1856-1866.
5. Ripamonti C, De Conno F, Groff L, Belzile M, Pereira J, Hanson J, Bruera E: Equianalgesic dose/ratio between methadone and other opioid agonists in cancer pain: Comparison of two clinical experiences. Ann Oncol 1998;9:79-83.
6. th Ed. Glenview, IL: The American Pain Society Press, 1999.
7. Lawlor P, Turner K, Hanson J, Bruera E: Dose ratio between morphine and hydromorphone in patients with cancer pain: A retrospective study. Pain 1997;72:79-85.
8. Lawlor PG, Turner KS, Hanson J, Bruera ED. Dose ratio between morphine and methadone in patients with cancer pain: A retrospective study. Cancer 1998;982:1167-1173.
9. Ripamonti C, Groff L, Brunelli C, Palaastri D, Starakis A, De Conno F: Switching from morphine to oral methadone in treating cancer pain: What is the equianalgesic dose ratio? J Clin Oncol 1998;16:3216-3221.
10. Pereira J. Lawlor P, Vigano A, Dorgan M, Bruera E: Equianalgesic dose ratios for opioids: A critical review and proposals for long-term dosing. J Pain Symptom Manage 2001;22:672-678.
11. Bruera E, Lawlor P, Watanabe S, Turner K, Hanson J: The effects of opioid rotation (OR), dose ratio (DR) on pain control and cognition in patients (P) with cancer pain. Presented at the A.S.C.O. Meeting in Denver, CO May 20, 1997. Proc ASCO 1997;16:62a.
12. Charrois T, Lindsay MA, Bruera E: Utilizing a morphine equivalent daily dose for comparison of opioid use in two palliative care units in Canada. Presented at the 12th International Congress on Care of the Terminally Ill, Montreal, PQ September 13-17, 1998. J Palliat Care 1998;14:117.
13. Gagnon B, Bruera E: Differences in the ratios of morphine to methadone in patients with neuropathic pain versus non-neuropathic pain. J Pain Symptom Manage 1999;18:120-125.
14. Lawlor P, Pereira J, Bruera E: Dose ratios among different opioids: underlying issues and an update on the use of the equianalgesic table. In: Bruera E, Portenoy RK (eds): Topics in Palliative Care, Volume 5. New York: Oxford University Press, 2001, pp. 247-276.
15. Lawlor PG, Quan H, Daeninck P, Hanson J, Bruera E: Dose Ratio of Oral to Subcutaneous Hydromorphone in Advanced Cancer Patients. Presented at 12th International Symposium-Supportive Care in Cancer. MASCC and ISOO. Washington, DC, March 23-25, 2000.
16. Lawlor PG, Daeninck P, Doyle J, Quan H, Hanson, J, Bruera E: Dose ratio of oral to subcutaneous morphine in the treatment of cancer pain. American Pain Society. Ft. Lauderdale, FL: October 21-24, 1999.
17. Lawlor P, Fan D, Hanson J, Bruera E: Equianalgesic conversion dose ratio of morphine (M) to hydromorphone (HM) in patients with cancer pain. Presented at the 11th International Congress on Care of the Terminally Ill. Montreal: September 7-11, 1996.
18. Pereira J, Bruera E, Watanabe S, Belzile M, Hanson J: Opioid rotation in patients with cancer pain: A retrospective comparison of dose ratios between methadone, hydromorphone and morphine. Presented at the 6th Canadian Palliative Care Conference "Setting our Sails, Advancing Care." Halifax, Nova Scotia: October 15-17, 1995.
19. Ripamonti C, De Conno F, Groff L, Belzile M, Pereira J, Hanson J, Bruera E: Equianalgesic dose/ratio between methadone and other opioid agonists in cancer pain: Comparison of two clinical experiences Ann Oncol 1998;9:79-83.