Citrulline blood levels as indicators of residual intestinal absorption in patients with short bowel syndrome

Annals of Nutrition and Metabolism

Volumn 53, Issue 2, 2008, Pages 137-142

  Santarpia, Lidia ^a   Catanzano, Francesca ^a,b   Ruoppolo, Margherita ^a   Alfonsi, Lucia ^a   Vitale, Dino Franco ^c   Pecce, Rita ^a   Pasanisi, Fabrizio ^a   Contaldo, Franco ^a   Salvatore, Francesco ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF SANNIO   (Italy)

^c IRCCS   (Italy)

Author keywords

Amino acids; Citrulline; High performance liquid chromatography; Short bowel syndrome; Tandem mass spectrometry

Indexed keywords

ALANINE; AMINO ACID; ARGININE; ASPARTIC ACID; CITRULLINE; GLUTAMIC ACID; GLUTAMINE; GLYCINE; ISOLEUCINE; LEUCINE; METHIONINE; ORNITHINE; PHENYLALANINE; TYROSINE; VALINE;

ADULT; AGED; AMINO ACID BLOOD LEVEL; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LONG TERM CARE; MALE; METHODOLOGY; PARENTERAL NUTRITION; PRIORITY JOURNAL; SHORT BOWEL SYNDROME; SMALL INTESTINE ABSORPTION; TANDEM MASS SPECTROMETRY;

ADULT; AMINO ACIDS; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CITRULLINE; FEMALE; HUMANS; INTESTINAL ABSORPTION; INTESTINE, SMALL; MALE; MIDDLE AGED; PARENTERAL NUTRITION; PREDICTIVE VALUE OF TESTS; SENSITIVITY AND SPECIFICITY; SHORT BOWEL SYNDROME;

EID: 55449119785     PISSN: 02506807     EISSN: None     Source Type: Journal    
DOI: 10.1159/000170888     Document Type: Article

References (20)

1. Rabier D, Kamoun P: Metabolism of citrulline in man. Amino Acids 1995;9:299-316.
2. Windmueller HG, Spaeth AE: Source and fate of circulating citrulline. Am J Physiol 1981;241:E473-E480.
3. Flynn NE, Wu G: An important role for endogenous synthesis of arginine in maintaining arginine homeostasis in neonatal pigs. Am J Physiol 1996;271:1149-1155.
4. Weber FL, Reiser BJ: Relationship of plasma amino acids to nitrogen balance and portal-systemic encephalopathy in alcoholic liver disease. Dig Dis Sci 1982;27:103-109.
5. Crenn P, Vahedi K, Lavergne-Slove A, Cynober L, Matuchansky C, Messing B: Plasma citrulline: a marker of enterocyte mass in villous atrophy-associated small bowel disease. Gastroenterology 2003;124:1210-1219.
6. Soeters PB, van de Poll MC, van Gemert WG, Dejong CH: Amino acid adequacy in pathophysiological state. J Nutr 2004;134:1575S-1582S.
7. Crenn P, Coudray-Lucas C, Thuiller F, Cynober L, Messing B: Postabsorbitive plasma citrulline concentration is a marker of absorptive enterocyte mass and intestinal failure in humans. Gastroenterology 2000;119:1496-1505.
8. Jianfeng G, Weiming Z, Ning L, Fangnan L, Li T, Nan L, et al: Serum citrulline is a simple quantitative marker for small intestinal enterocytes mass and absorption function in short bowel patients. J Surg Res 2005;127:177-182.
9. Lou M. Fernández-Estivariz C, Manatunga AK, et al: Are plasma citrulline and glutamine biomarkers of intestinal absorptive function in patients with short bowel syndrome? JPEN 2007;31:1-7.
10. Weseman R, DiBaise JK, Sudan D, Brown C, Byrne TA: Successful restoration of nutritional autonomy in short bowel syndrome (SBS) patients with very low plasma citrulline concentration. Nutr Clin Pract 2004;19:86-87.
11. Jones PM, Bennett MJ: The changing face of newborn screening: diagnosis of inborn errors of metabolism by tandem mass spectrometry. Clin Chim Acta 2002;324:121-128.
12. Chace DH, Kalas T: A biochemical perspective on the use of tandem mass spectrometry for newborn screening and clinical testing. Clin Biochem 2005;38:296-309.
13. Nightingale JM, Bartram CI, Lennard-Jones JE: Length of residual small bowel after partial resection: correlation between radiographic and surgical measurements. Gastrointest Radiol 1991;16:305-306.
14. Cummings JH, James WP, Wiggins HS: Role of the colon in ileal-resection diarrhoea. Lancet 1973;17:344-347.
15. Parvy PR, Bardet JI, Rabier DM, Saudubray JM, Kamoun PP: Ion exchange chromatography and clinical criteria in the screening of the aminoacidopathies. Clin Chim Acta 1998;176:269-278.
16. Dettmer K, Aronov PA, Hammock BD: Mass spectrometry-based metabolomics. Mass Spectrom Rev 2007;26:51-78.
17. Qian WJ, Jacobs JM, Liu T, Camp DG, Smith RD: Advances and challenges in liquid chromatography-mass spectrometry based proteomic profiling for clinical applications. Mol Cell Proteomics 2006;5:1727-1744.
18. Violante G, Alfonsi L, Santarpia L, Cillis MC, Negro G, De Caprio C, Russo N, et al: Adult home parenteral nutrition: a clinical evaluation after a 3-year experience in a Southern European centre. Eur J Clin Nutr 2006;1:58-61.
19. Santarpia L, Alfonsi L, Pasanisi F, De Caprio C, Scalfi L, Contaldo F: Predictive factors of survival in patients with peritoneal carcinomatosis on home parenteral nutrition. Nutrition 2006;22:355-360.
20. Yu HC, Tuteja S, Moon JI, Kleiner GI, Conanan L, Gaynor JJ, Kato T, Levi DM, Nishida S, et al: Utilization of dried blood spot citrulline level as a non-invasive method for monitoring graft function following intestinal transplantation. Transplantation 2005;80:1729-1733.