Acute exercise-induced changes in basal VLDL-triglyceride kinetics leading to hypotriglyceridemia manifest more readily after resistance than endurance exercise

Journal of Applied Physiology

Volumn 105, Issue 4, 2008, Pages 1228-1236

  Magkos, Faidon ^a   Tsekouras, Yiannis E ^a   Prentzas, Konstantinos I ^a   Basioukas, Konstantinos N ^a   Matsama, Stergoula G ^a   Yanni, Amalia E ^a   Kavouras, Stavros A ^a   Sidossis, Labros S ^a  

^a HAROKOPIO UNIVERSITY   (Greece)

Author keywords

Aerobic; Isokinetic; Lipid kinetics; Physical activity; Triacylglycerol

Indexed keywords

TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN; INSULIN; VERY LOW DENSITY LIPOPROTEIN TRIGLYCERIDE;

ADULT; AIRWAY RESISTANCE; ARTICLE; CONTROLLED STUDY; ENDURANCE; ENERGY EXPENDITURE; HUMAN; HUMAN EXPERIMENT; INSULIN BLOOD LEVEL; ISOTOPE LABELING; MALE; METABOLIC RATE; NORMAL HUMAN; OXYGEN CONSUMPTION; PLASMA CLEARANCE; PRIORITY JOURNAL; TREADMILL EXERCISE; BLOOD; CARBOHYDRATE METABOLISM; COMPARATIVE STUDY; DOWN REGULATION; ENERGY METABOLISM; EXERCISE; GLUCOSE BLOOD LEVEL; KINETICS; LIPID METABOLISM; LIPOPROTEIN DEFICIENCY; LIVER; METABOLISM; OXIDATION REDUCTION REACTION; PATHOPHYSIOLOGY;

ADULT; BLOOD GLUCOSE; CARBOHYDRATE METABOLISM; DOWN-REGULATION; ENERGY METABOLISM; EXERCISE; HUMANS; HYPOLIPOPROTEINEMIAS; INSULIN; KINETICS; LIPID METABOLISM; LIPOPROTEINS, VLDL; LIVER; MALE; OXIDATION-REDUCTION; PHYSICAL ENDURANCE; TRIGLYCERIDES;

EID: 55449114312     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.90761.2008     Document Type: Article

References (66)

1. Alessio HM, Hagerman AE, Fulkerson BK, Ambrose J, Rice RE, Wiley RL. Generation of reactive oxygen species after exhaustive aerobic and isometric exercise. Med Sci Sports Exerc 32: 1576-1581, 2000.
2. American College of Sports Medicine. ACSM's Guidelines for Exercise Testing and Prescription. Philadelphia, PA: Lippincott Williams & Wilkins, 2000.
3. American College of Sports Medicine. Position Stand: The recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness, and flexibility in healthy adults. Med Sci Sports Exerc 30: 975-991, 1998.
4. Angelopoulos TJ, Robertson RJ. Effect of a single exercise bout on serum triglycerides in untrained men. J Sports Med Phys Fitness 33: 264-267, 1993.
5. 3-C. Int J Sports Med 14: 196-201, 1993.
6. Annuzzi G, Jansson E, Kaijser L, Holmquist L, Carlson LA. Increased removal rate of exogenous triglycerides after prolonged exercise in man: time course and effect of exercise duration. Metabolism 36: 438-443, 1987.
7. Bassuk SS, Manson JE. Epidemiological evidence for the role of physical activity in reducing risk of type 2 diabetes and cardiovascular disease. J Appl Physiol 99: 1193-1204, 2005.
8. Berlin JA, Colditz GA. A meta-analysis of physical activity in the prevention of coronary heart disease. Am J Epidemiol 132: 612-628, 1990.
9. Budohoski L. Exercise-induced changes in lipoprotein lipase activity (LPLA) in skeletal muscles of the dog. Pflügers Arch 405: 188-192, 1985.
10. Burleson MA Jr, O'Bryant HS, Stone MH, Collins MA, Triplett-McBride T. Effect of weight training exercise and treadmill exercise on post-exercise oxygen consumption. Med Sci Sports Exerc 30: 518-522, 1998.
11. Burns SF, Corrie H, Holder E, Nightingale T, Stensel DJ. A single session of resistance exercise does not reduce postprandial lipaemia. J Sports Sci 23: 251-260, 2005.
12. Burns SF, Miyashita M, Ueda C, Stensel DJ. Multiple bouts of resistance exercise and postprandial triacylglycerol and serum C-reactiveprotein concentrations. Int J Sport Nutr Exerc Metab 17: 556-573, 2007.
13. Crouse SF, O'Brien BC, Rohack JJ, Lowe RC, Green JS, Tolson H, Reed JL. Changes in serum lipids and apolipoproteins after exercise in men with high cholesterol: influence of intensity. J Appl Physiol 79: 279-286, 1995.
14. Cullinane E, Siconolfi S, Saritelli A, Thompson PD. Acute decrease in serum triglycerides with exercise: is there a threshold for an exercise effect? Metabolism 31: 844-847, 1982.
15. Dufaux B, Order U, Muller R, Hollmann W. Delayed effects of prolonged exercise on serum lipoproteins. Metabolism 35: 105-109, 1986.
16. Durstine JL, Grandjean PW, Cox CA, Thompson PD. Lipids, lipoproteins, exercise. J Cardiopulm Rehabil 22: 385-398, 2002.
17. Ferrannini E. The theoretical bases of indirect calorimetry: a review. Metabolism 37: 287-301, 1988.
18. Fisher RM, Coppack SW, Humphreys SM, Gibbons GF, Frayn KN. Human triacylglycerol-rich lipoprotein subfractions as substrates for lipoprotein lipase. Clin Chim Acta 236: 7-17, 1995.
19. Gill JM, Frayn KN, Wootton SA, Miller GJ, Hardman AE. Effects of prior moderate exercise on exogenous and endogenous lipid metabolism and plasma factor VII activity. Clin Sci (Lond) 100: 517-527, 2001.
20. Gill JM, Hardman AE. Postprandial lipemia: effects of exercise and restriction of energy intake compared. Am J Clin Nutr 71: 465-471, 2000.
21. Gillette CA, Bullough RC, Melby CL. Postexercise energy expenditure in response to acute aerobic or resistive exercise. Int J Sport Nutr 4: 347-360, 1994.
22. Gordon PM, Goss FL, Visich PS, Warty V, Denys BJ, Metz KF, Robertson RJ. The acute effects of exercise intensity on HDL-C metabolism. Med Sci Sports Exerc 26: 671-677, 1994.
23. Grandjean PW, Crouse SF, Rohack JJ. Influence of cholesterol status on blood lipid and lipoprotein enzyme responses to aerobic exercise. J Appl Physiol 89: 472-480, 2000.
24. Gyntelberg F, Brennan R, Holloszy JO, Schonfeld G, Rennie MJ, Weidman SW. Plasma triglyceride lowering by exercise despite increased food intake in patients with type IV hyperlipoproteinemia. Am J Clin Nutr 30: 716-720, 1977.
25. Hardman AE, Lawrence JE, Herd SL. Postprandial lipemia in endurance-trained people during a short interruption to training. J Appl Physiol 84: 1895-1901, 1998.
26. Herd SL, Hardman AE, Boobis LH, Cairns CJ. The effect of 13 weeks of running training followed by 9 d of detraining on postprandial lipaemia. Br J Nutr 80: 57-66, 1998.
27. Herd SL, Kiens B, Boobis LH, Hardman AE. Moderate exercise, postprandial lipemia, and skeletal muscle lipoprotein lipase activity. Metabolism 50: 756-762, 2001.
28. Hildebrandt AL, Pilegaard H, Neufer PD. Differential transcriptional activation of select metabolic genes in response to variations in exercise intensity and duration. Am J Physiol Endocrinol Metab 285: E1021-E1027, 2003.
29. Holloszy JO, Skinner JS, Toro G, Cureton TK. Effects of a six month program of endurance exercise on the serum lipids of middle-aged men. Am J Cardiol 14: 753-760, 1964.
30. Hurley BF. Effects of resistive training on lipoprotein-lipid profiles: a comparison to aerobic exercise training. Med Sci Sports Exerc 21: 689-693, 1989.
31. Katsanos CS, Grandjean PW, Moffatt RJ. Effects of low and moderate exercise intensity on postprandial lipemia and postheparin plasma lipoprotein lipase activity in physically active men. J Appl Physiol 96: 181-188, 2004.
32. Kiens B, Richter EA. Utilization of skeletal muscle triacylglycerol during postexercise recovery in humans. Am J Physiol Endocrinol Metab 275: E332-E337, 1998.
33. Knuttgen HG. Strength training and aerobic exercise: comparison and contrast. J Strength Cond Res 21: 973-978, 2007.
34. Lamarche B, Uffelman KD, Carpentier A, Cohn JS, Steiner G, Barrett PH, Lewis GF. Triglyceride enrichment of HDL enhances in vivo metabolic clearance of HDL apo A-I in healthy men. J Clin Invest 103: 1191-1199, 1999.
35. 5]glycerol bolus to measure very low density lipoprotein triglyceride kinetics in humans. J Lipid Res 40: 2111-2117, 1999.
36. Magkos F, Patterson BW, Mittendorfer B. Reproducibility of stable isotope-labeled tracer measures of VLDL-triglyceride and VLDL-apolipoprotein B-100 kinetics. J Lipid Res 48: 1204-1211, 2007.
37. Magkos F, Patterson BW, Mohammed BS, Klein S, Mittendorfer B. Women produce fewer but triglyceride-richer very low-density lipoproteins than men. J Clin Endocrinol Metab 92: 1311-1318, 2007.
38. Magkos F, Patterson BW, Mohammed BS, Mittendorfer B. A single 1-h bout of evening exercise increases basal FFA flux without affecting VLDL-triglyceride and VLDL-apolipoprotein B-100 kinetics in untrained lean men. Am J Physiol Endocrinol Metab 292: E1568-E1574, 2007.
39. Magkos F, Wright DC, Patterson BW, Mohammed BS, Mittendorfer B. Lipid metabolism response to a single, prolonged bout of endurance exercise in healthy young men. Am J Physiol Endocrinol Metab 290: E355-E362, 2006.
40. Malkova D, Evans RD, Frayn KN, Humphreys SM, Jones PR, Hardman AE. Prior exercise and postprandial substrate extraction across the human leg. Am J Physiol Endocrinol Metab 279: E1020-E1028, 2000.
41. Malkova D, Hardman AE, Bowness RJ, Macdonald IA. The reduction in postprandial lipemia after exercise is independent of the relative contributions of fat and carbohydrate to energy metabolism during exercise. Metabolism 48: 245-251, 1999.
42. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and betacell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419, 1985.
43. Melby C, Scholl C, Edwards G, Bullough R. Effect of acute resistance exercise on postexercise energy expenditure and resting metabolic rate. J Appl Physiol 75: 1847-1853, 1993.
44. Miyashita M, Tokuyama K. Moderate exercise reduces serum triacylglycerol concentrations but does not affect preheparin lipoprotein lipase concentrations after a moderate-fat meal in young men. Br J Nutr 99: 1076-1082, 2008.
45. Pan M, Cederbaum AI, Zhang YL, Ginsberg HN, Williams KJ, Fisher EA. Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production. J Clin Invest 113: 1277-1287, 2004.
46. Patterson BW, Mittendorfer B, Elias N, Satyanarayana R, Klein S. Use of stable isotopically labeled tracers to measure very low density lipoprotein-triglyceride turnover. J Lipid Res 43: 223-233, 2002.
47. Peronnet F, Massicotte D. Table of nonprotein respiratory quotient: an update. Can J Sport Sci 16: 23-29, 1991.
48. Petitt DS, Arngrimsson SA, Cureton KJ. Effect of resistance exercise on postprandial lipemia. J Appl Physiol 94: 694-700, 2003.
49. Scott CB. Contribution of blood lactate to the energy expenditure of weight training. J Strength Cond Res 20: 404-411, 2006.
50. Seip RL, Semenkovich CF. Skeletal muscle lipoprotein lipase: molecular regulation and physiological effects in relation to exercise. Exerc Sport Sci Rev 26: 191-218, 1998.
51. Shannon KA, Shannon RM, Clore JN, Gennings C, Warren BJ, Potteiger JA. Resistance exercise and postprandial lipemia: the dose effect of differing volumes of acute resistance exercise bouts. Metabolism 54: 756-763, 2005.
52. Shephard RJ. Cytokine responses to physical activity, with particular reference to IL-6: sources, actions, and clinical implications. Crit Rev Immunol 22: 165-182, 2002.
53. Streja D, Kallai MA, Steiner G. The metabolic heterogeneity of human very low density lipoprotein triglyceride. Metabolism 26: 1333-1344, 1977.
54. Thompson PD, Cullinane E, Henderson LO, Herbert PN. Acute effects of prolonged exercise on serum lipids. Metabolism 29: 662-665, 1980.
55. Tsekouras YE, Magkos F, Prentzas KI, Basioukas KN, Matsama SG, Yanni AE, Kavouras SA, Sidossis LS. A single bout of whole-body resistance exercise augments basal VLDL-triacylglycerol removal from plasma in healthy untrained men. Clin Sci (Lond): June 13, 2008.
56. Tsekouras YE, Yanni AE, Bougatsas D, Kavouras SA, Sidossis LS. A single bout of brisk walking increases basal very low-density lipoprotein triacylglycerol clearance in young men. Metabolism 56: 1037-1043, 2007.
57. Tsetsonis NV, Hardman AE. Effects of low and moderate intensity treadmill walking on postprandial lipaemia in healthy young adults. Eur J Appl Physiol 73: 419-426, 1996.
58. Tsetsonis NV, Hardman AE. Reduction in postprandial lipemia after walking: influence of exercise intensity. Med Sci Sports Exerc 28: 1235-1242, 1996.
59. Tsetsonis NV, Hardman AE. The influence of the intensity of treadmill walking upon changes in lipid and lipoprotein variables in healthy adults. Eur J Appl Physiol 70: 329-336, 1995.
60. Uchiyama S, Shimizu T, Shirasawa T. CuZn-SOD deficiency causes ApoB degradation and induces hepatic lipid accumulation by impaired lipoprotein secretion in mice. J Biol Chem 281: 31713-31719, 2006.
61. van Loon LJ, Thomason-Hughes M, Constantin-Teodosiu D, Koopman R, Greenhaff PL, Hardie DG, Keizer HA, Saris WH, Wagenmakers AJ. Inhibition of adipose tissue lipolysis increases intramuscular lipid and glycogen use in vivo in humans. Am J Physiol Endocrinol Metab 289: E482-E493, 2005.
62. Vincent HK, Morgan JW, Vincent KR. Obesity exacerbates oxidative stress levels after acute exercise. Med Sci Sports Exerc 36: 772-779, 2004.
63. Wilmore JH, Costill DL. Physiology of Sport and Exercise. Champaign, IL: Human Kinetics, 1999.
64. Yamada T, Kurasawa S, Matsuzaki M, Tanaka A. Remnant lipoprotein metabolism is improved more when body weight is reduced by exercise than by dietary restriction. Clin Chim Acta 388: 28-32, 2008.
65. Zafeiridis A, Goloi E, Petridou A, Dipla K, Mougios V, Kellis S. Effects of low- and high-volume resistance exercise on postprandial lipaemia. Br J Nutr 97: 471-477, 2007.
66. Zhang JQ, Smith B, Langdon MM, Messimer HL, Sun GY, Cox RH, James-Kracke M, Thomas TR. Changes in LPLa and reverse cholesterol transport variables during 24-h postexercise period. Am J Physiol Endocrinol Metab 283: E267-E274, 2002.