Allergen-sensitization increases mast-cell expression of the exocytotic proteins SNAP-23 and syntaxin 4, which are involved in histamine secretion

Journal of Investigational Allergology and Clinical Immunology

Volumn 18, Issue 5, 2008, Pages 366-371

  Salinas, Eva ^a,b   Quintanar Stephano, A ^a   Cordova L E ^a   Quintanar, J L ^a  

^a UNIVERSIDAD AUTÓNOMA DE AGUASCALIENTES   (Mexico)

^b NONE   (Mexico)

Author keywords

Histamine; Mast cells; Sensitization; SNAP 23; Syntaxin 4

Indexed keywords

HISTAMINE; OVALBUMIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 23; SYNTAXIN 4;

ALLERGY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; EXOCYTOSIS; HISTAMINE RELEASE; MALE; MAST CELL; NONHUMAN; PASSIVE SKIN ANAPHYLAXIS; PROTEIN FUNCTION; RAT; SENSITIZATION; WESTERN BLOTTING;

ANIMALS; CAPILLARY PERMEABILITY; CELLS, CULTURED; DESENSITIZATION, IMMUNOLOGIC; EXOCYTOSIS; GENE EXPRESSION REGULATION; HISTAMINE RELEASE; IMMUNIZATION; MALE; MAST CELLS; OVALBUMIN; PASSIVE CUTANEOUS ANAPHYLAXIS; QA-SNARE PROTEINS; QB-SNARE PROTEINS; QC-SNARE PROTEINS; RATS; RATS, WISTAR;

EID: 55449102975     PISSN: 10189068     EISSN: 16980808     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Prussin C, Metcalfe DD. IgE, mast cells, basophils, and eosinophils. J. Allergy. Clin. Immunol. 2006;117:S450-6.
2. Guo Z, Turner C, Castle D. Relocation of the t-SNARE SNAP-23 from lamellipodia-like cell surface projections regulates compound exocytosis in mast cells. Cell 1998;94:537-48.
3. Paumet F, le Mao J, Martín S, Galli T, David B, Blank U, Roa M. Soluble NSF attachment proteins receptors (SNAREs) in RBL-2H3 mast cells: functional role of syntaxin 4 in exocytosis and identification of a vesicle-associated membrane protein 8-containing secretory compartment. J. Immunol. 2000;164:5850-7.
4. Kawakami T, Kitaura J. Mast cell survival and activation by IgE in the absence of antigen: a consideration of the biologic mechanisms and relevance. J. Immunol. 2005;175:4167-73.
5. Yamaguchi M, Lantz CS, Oettgen HC, Katona IM, Fleming T, Miyajima I, Kinet J-P, Galli SJ. IgE enhances mouse mast cell FceRI expression in vitro and in vivo: evidence for a novel amplification mechanisms in IgE-dependent reactions. J. Exp. Med. 1997;17:663-72.
6. Kitaura J, Song J, Tsai M, Asai K, Maeda-Yamamoto M, Mocsai A, Kawakami Y, Liu F-T, Lowell CA, Barisas BG, Galli SJ, Kawakami T. Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the FcεRI. Proc. Natl. Acad. Sci. USA 2003;100:12911-6.
7. Dai Y, Hou LF, Chan YP, Cheng L, But PPH. Inhibition of immediate allergic reactions by ethanol extract from Plumbago zeylanica Stems. Biol. Pharm. Bull 2004;27:429-32.
8. Salinas E, Ventura J, Córdova LE, Quintanar JL. Presence of SNAP-25 in rat mast cells. Immunol. Lett. 2004;95:105-8.
9. Laemmli UK. Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature. 1970;227:680-5.
10. Towbin H, Staehelin J, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Proc. Natl. Acad. Sci. USA 1979;76:4350-4.
11. Koopman WR, Jackson RC. Calcium- and guanine-nucleotide-dependent exocytosis in permeabilized rat mast cells. Biochem. J. 1990;256:365-73.
12. Shore PA, Burkhalter A, Cohn Jr VH. A method for the fluorometric assay of histamine in tissues. J. Pharmacol. Exp. Ther. 1959;127:182-6.
13. Pagan JK, Wylie FG, Joesph S, Widberg C, Bryant NJ, James DE, Stow JL. The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion. Curr. Biol. 2003;13:156-60.
14. Morikawa Y, Nishida H, Misawa K, Nosaka T, Miyajima A, Senba E, Kitamura T. Induction of synaptosomal-associated protein-23 kD (SNAP-23) by various cytokines. Blood. 1998;92:129-35.
15. Baram D, Adachi R, Medalla O, Tuvim M, Dickey BF, Mekori YA, Sagi-Eisenberg R. Synaptotagmin II negatively regulates Ca+2-triggered exocytosis of lysosomes in mast cells. J. Exp. Med 1999;189:1649-57.