Androgen receptor overexpression in Becker nevus: Histopathologic and immunohistochemical analysis

Journal of Cutaneous Pathology

Volumn 35, Issue 12, 2008, Pages 1121-1126

  Kim, Young Jin ^a   Han, Jae Ho ^a   Kang, Hee Young ^a   Lee, Eun So ^a   Kim, You Chan ^a  

^a Ajou University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; MELAN A; PROTEIN S 100;

ADOLESCENT; ADULT; ARTICLE; BECKER NEVUS; CAFE AU LAIT SPOT; CELL COUNT; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; LENTIGO; MALE; MELANOCYTE; PROTEIN EXPRESSION; PUNCH BIOPSY;

ADOLESCENT; ADULT; ANTIGENS, NEOPLASM; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; INFANT; MALE; MELANINS; MELANOCYTES; NEOPLASM PROTEINS; NEVUS, PIGMENTED; RECEPTORS, ANDROGEN; S100 PROTEINS; SKIN NEOPLASMS;

EID: 55349147717     PISSN: 03036987     EISSN: 16000560     Source Type: Journal    
DOI: 10.1111/j.1600-0560.2008.00988.x     Document Type: Article

References (18)

1. Danarti R, Konig A, Salhi A, et al. Becker's nevus syndrome revisited. J Am Acad Dermatol 2004 51 : 965.
2. Szylit JA, Grossman ME, Luyando Y, et al. Becker's nevus and an accessory scrotum: a unique occurrence. J Am Acad Dermatol 1986 14 : 905.
3. Jung JH, Kim YC, Park HJ, Cinn YW. Becker's nevus with ipsilateral breast hypoplasia: improvement with spironolactone. J Dermatol 2003 30 : 154.
4. Person JR, Longcope C. Becker's nevus: an androgen-mediated hyperplasia with increased androgen receptors. J Am Acad Dermatol 1984 10 : 235.
5. Formigon M, Alsina MM, Mascaro JM, Rivera F. Becker's nevus and ipsilateral breast hypoplasia: androgen-receptor study in two patients. Arch Dermatol 1992 128 : 992.
6. Nirde P, Dereure O, Belon C, et al. The association of Becker nevus with hypersensitivity to androgens. Arch Dermatol 1999 135 : 212.
7. Tate PR, Hodge SJ, Owen LG. A quantitative study of melanocytes in Becker's nevus. J Cutan Pathol 1980 7 : 404.
8. Panizzon R, Brungger H, Vogel A. Becker nevus. A clinico-histopathologic- electron microscopy study of 39 patients. Hautarzt 1984 35 : 578.
9. Haneke E. The dermal component in melanosis naeviformis Becker. J Cutan Pathol 1979 6 : 53.
10. Bhawan J, Chang WH. Becker's melanosis: an ultrastructural study. Dermatologica (Basel) 1979 159 : 221.
11. Shi S-R, Cote RJ, Chaiwun B, Taylor CR. Standardization of immunohistochemistry based on antigen retrieval technique for routine formalin-fixed tissue sections. Appl Immunohistochem 1998 6 : 89.
12. Kang WH, Yoon KH, Lee E-S, et al. Melasma: histopathological characteristics in 56 Korean patients. Br J Dermatol 2002 146 : 228.
13. Karo KR, Gange RW. Smooth-muscle hamartoma. Possible congenital Becker's nevus. Arch Dermatol 1981 117 : 678.
14. Frenk E, Delacretaz J. Ultrastructure of Becker's melanosis. Hautarzt 1970 21 : 397.
15. Oyler RM, Davis DA, Woosley JT. Lymphangioma associated with Becker's nevus: a report of coincident hamartomas in a child. Pediatr Dermatol 1997 14 : 376.
16. Fretzin DF, Whitney D. Familial Becker's nevus. J Am Acad Dermatol 1985 12 : 589.
17. Tadokoro T, Rouzaud F, Itami S, et al. The inhibitory effect of androgen and sex-hormone-binding globulin on the intracellular cAMP level and tyrosinase activity of normal human melanocytes. Pigment Cell Res 2003 16 : 190.
18. Vottero A, Capelletti M, Giuliodori S, et al. Decreased androgen receptor gene methylation in premature pubarche: a novel pathogenetic mechanism? J Clin Endocrinol Metab 2006 91 : 968.