Baylis-Hillman reactions of 2-(trifluoroacetyl)-1,3-azoles

Synthesis

Volumn , Issue 20, 2008, Pages 3245-3252

  Khodakovskiy, Pavel V ^a,b   Volochnyuk, Dmitriy M ^a,c   Shivanyuk, Alexander ^a,b   Shishkin, Oleg V ^d   Tolmachev, Andrey A ^b  

^a ENAMINE LTD   (Ukraine)

^b TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV   (Ukraine)

^c INSTITUTE OF ORGANIC CHEMISTRY   (Ukraine)

^d INSTITUTE FOR SCINTILLATION MATERIALS   (Ukraine)

Author keywords

1,3 Azoles; Allylic alcohols; Baylis Hillman reaction; Michael additions; Trifluoromethyl substituted

Indexed keywords

CHEMICAL REACTIONS;

1,3-AZOLES; ALLYLIC ALCOHOLS; BAYLIS-HILLMAN REACTION; MICHAEL ADDITIONS; TRIFLUOROMETHYL SUBSTITUTED;

ADDITION REACTIONS;

PYRROLE DERIVATIVE;

ARTICLE; BAYLIS HILLMAN REACTION; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CYCLIZATION; FLUORINE NUCLEAR MAGNETIC RESONANCE; MICHAEL ADDITION; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 55349144525     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0028-1083150     Document Type: Article

References (8)

1. (a) Basavaiah, D.; Venkateswara Rao, K.; Reddy, R. J. Chem. Soc. Rev. 2007, 36, 1581.
2. (b) Basavaiah, D.; Jaganmohan Rao, A.; Satyanarayana, T. Chem. Rev. 2003, 103, 811.
3. 3 Ketones: Golubev, A. S.; Kolomiets, A. F.; Fokin, A. V. J. Fluorine Chem. 1991, 54, 272.
4. (b) Isatins, ninhydrin: Chung, Y. M.; Im, Y. J.; Kim, J. N. Bull. Korean Chem. Soc. 2002, 23, 1651.
5. Common ketones: Hill, J. S.; Isaacs, N. S. Tetrahedron Lett. 1986, 27, 5007.
6. Khodakovskiy, P. V.; Volochnyuk, D. M.; Panov, D. M.; Pervak, I.I.; Zarudnitskii, E. V.; Shishkin, O. V.; Yurchenko, A. A.; Shivanyuk, A.; Tolmachev, A. A. Synthesis 2008, 948.
7. For analogous transformation of BH products see: Batra, S.; Roy, A. K.; Patra, A.; Bhaduri, A. P.; Surin, W. R.; Raghavan, S. A. V.; Sharma, P.; Kapoor, K.; Dikshit, M. Bioorg. Med. Chem. 2004, 12, 2059.
8. Sheldrick, G. M. SHELXTL PLUS, PC Version; a system of computer programs for the determination of crystal structure from X-ray diffraction data; Rev.5.1, 1998.