Temocillin in cystic fibrosis: A retrospective pilot study

Journal of Cystic Fibrosis

Volumn 7, Issue 6, 2008, Pages 551-554

  Kent, Lisa ^a,b   Bradley, Judy M ^a,b   France, Megan ^c   Döring, Gerd ^d   Carryn, Stéphane ^e   Bradbury, Ian ^f   Rendall, Jackie ^a   Jones, Andrew ^c   Elborn, J Stuart ^a,f  

^a BELFAST CITY HOSPITAL   (United Kingdom)

^b UNIVERSITY OF ULSTER   (United Kingdom)

^c WYTHENSHAWE HOSPITAL   (United Kingdom)

^d UNIVERSITY OF TÜBINGEN   (Germany)

^e UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^f QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Burkholderia cepacia complex; Pseudomonas aeruginosa; Temocillin

Indexed keywords

AMIKACIN; ANTIBIOTIC AGENT; AZTREONAM; CEFTAZIDIME; CHLORAMPHENICOL; CIPROFLOXACIN; COLISTIN; COTRIMOXAZOLE; DOXYCYCLINE; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM; TEMOCILLIN; TIMENTIN; TOBRAMYCIN;

ADULT; ARTICLE; BURKHOLDERIA CEPACIA COMPLEX; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; DISEASE EXACERBATION; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LUNG FUNCTION; MALE; PILOT STUDY; PSEUDOMONAS AERUGINOSA; RESPIRATORY TRACT INFECTION; RETROSPECTIVE STUDY; TREATMENT OUTCOME;

ADULT; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; BURKHOLDERIA CEPACIA; BURKHOLDERIA INFECTIONS; COHORT STUDIES; CROSS-OVER STUDIES; CYSTIC FIBROSIS; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; PENICILLINS; PILOT PROJECTS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RESPIRATORY TRACT INFECTIONS; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 55349136547     PISSN: 15691993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcf.2008.06.005     Document Type: Article

References (20)

1. Rodriguez-Villalobos H., Malavoille V., Frankard J., de Mendonca R., Nonhoff C., and Struelens M.J. In vitro activity of temocillin against extended spectrum beta-lactamase-producing Escherichia coli. J Antimicrob Chemother 57 4 (2006) 771-774
2. Edmondson R.A., and Reading C. Beta-lactamase stability of temocillin. Drugs 29 suppl 5 (1985) 64-66
3. Stapleton P., Shannon K., and Phillips I. The ability of beta-lactam antibiotics to select mutants with depressed beta-lactamase synthesis from Citobacter freundii. J Antimicrob Chemother 36 3 (1995) 483-496
4. Chen H.Y., and Williams J.D. The Activity of temocillin against Enerobacteriaceae, Pseudomonas and Haemophilus influenzae. Drugs 29 Suppl 5 (1985) 85-90
5. VIM-1-containing integron from a Pseudomonas aeruginosa clinical isolate. Antimicrob Agents Chemother 49 5 (2005) 1973-1980
6. Bauernfeind A. Bacteriostatic and bactericidal activity of penicillins at constant and variable concentrations. Drugs 29 Suppl 5 (1985) 9-14
7. Martinez-Beltran J., Loza E., Gomez-Alferez A., Romero-Vivas J., and Bouza E. Temocillin: in-vitro activity compared to other antibiotics. Drugs 29 Suppl 5 (1985) 91-97
8. Jules K., and Neu H.C. Antibacterial activity and beta-lactamase stability of temocillin. Antimicrob Agents Chemother 22 3 (1982) 453-460
9. Verbist L., and Verhaegen J. Effect of temocillin in combination with other beta-lactam antibiotics. Antimicrob Agents Chemother 25 1 (1984) 142-144
10. Bolivar R., Weaver S.S., and Bodey G.P. Comparative in vitro study of temocillin (BRL 17421), a new penicillin. Antimicrob Agents Chemother 21 4 (1982) 641-645
11. Boon R.J., and Beale A.S. Studies with temocillin in the hamster model of antibiotic-associated colitis. Drugs 29 Suppl 5 (1985) 57-63
12. Tanphaichitra D., Kanjanapanjapol S., Srimuang S., and Robinson O. Use of temocillin in typhoid fever, hepatobiliary disease and other infections. Drugs 29 Suppl 5 (1985) 201-205
13. Legge J.S., Reid T.M., and Palmer J.B. Clinical efficacy, tolerance and pharmacokinetics of temocillin in patients with respiratory tract infections. Drugs 29 Suppl 5 (1985) 118-121
14. Verbist L. In vitro activity of temocillin (BRL 17421), a novel beta-lactamase-stable penicillin. Antimicrob Agents Chemother 22 1 (1982) 157-161
15. Williams J.D., and Chen H.Y. The place of temocillin in the treatment of hospital infections. Drugs 29 Suppl 5 (1985) 234-239
16. Lekkas A., Gyi K.M., and Hodson M.E. Temocillin in the treatment of Burkholderia cepacia infection in cystic fibrosis. J Cyst Fibros 5 (2006) 121-124
17. Slocombe B., Cooper C.E., Griffen K.E., and White A.R. Temocillin. In vitro antibacterial activity. Drugs 29 Suppl 5 (1985) 49-56
18. Bonacorsi S., Fitoussi F., Lhopital S., and Bingen E. Comparative in vitro activities of meropenem, imipenem, temocillin, piperacillin, and ceftazidime in combination with tobramycin, rifampin, or ciprofloxacin against Burkholderia cepacia isolates from patients with cystic fibrosis. Antimicrob Agents Chemother 43 2 (1999) 213-217
19. Taylor R.F., Gaya H., and Hodson M.E. Temocillin and cystic fibrosis: outcome of intravenous administration in patients infected with Pseudomonas cepacia. J Antimicrob Chemother 29 3 (1992) 341-344
20. Gray J.M., Leiper J.M., Lawson D.H., Cowan W., Baird A., and Sleigh J.D. Temocillin in the treatment of chest infections. Drugs 29 Suppl 5 (1985) 197-200