Generalized and neurotransmitter-selective noradrenergic denervation in Parkinson's disease with orthostatic hypotension

Movement Disorders

Volumn 23, Issue 12, 2008, Pages 1725-1732

  Sharabi, Yehonatan ^a   Imrich, Richard ^a   Holmes, Courtney ^a   Pechnik, Sandra ^a   Goldstein, David S ^a,b  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b NONE   (United States)

Author keywords

Dysautonomia; Multiple system atrophy; Noradrenergic; Parkinson's disease

Indexed keywords

3,4 DIHYDROXYPHENYLETHYLENE GLYCOL; EDROPHONIUM CHLORIDE; GLUCAGON; ISOPRENALINE; NORADRENALIN; TYRAMINE; YOHIMBINE;

ADULT; AGED; ARTICLE; AUTONOMIC DENERVATION; BRADYCARDIA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG DOSE INCREASE; FEMALE; HUMAN; MALE; MICRODIALYSIS; NEUROCHEMISTRY; NORADRENALIN BLOOD LEVEL; NORADRENERGIC DENERVATION; NORADRENERGIC NERVE; NORADRENERGIC SYSTEM; ORTHOSTATIC HYPOTENSION; PARKINSON DISEASE; PRIORITY JOURNAL; SKELETAL MUSCLE;

AGED; BLOOD PRESSURE; BRADYCARDIA; CHOLINESTERASE INHIBITORS; EDROPHONIUM; EPINEPHRINE; FEMALE; GLUCAGON; HUMANS; HYPOTENSION, ORTHOSTATIC; ISOPROTERENOL; MALE; METHOXYHYDROXYPHENYLGLYCOL; MICRODIALYSIS; MIDDLE AGED; MUSCLE, SKELETAL; NOREPINEPHRINE; PARKINSON DISEASE; PURE AUTONOMIC FAILURE; TYRAMINE; YOHIMBINE;

EID: 55349121610     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.22226     Document Type: Article

References (43)

1. Kaufmann H, Biaggioni I. Autonomic failure in neurodegenerative disorders. Semin Neurol 2003;23:351-363.
2. Goldstein DS. Orthostatic hypotension as an early finding in Parkinson disease. Clin Auton Res 2006;16:46-64.
3. Goldstein DS, Tack C. Non-invasive detection of sympathetic neurocirculatory failure. Clin Auton Res 2000;10:285-291.
4. Goldstein DS, Holmes C, Cannon RO, III et al. Sympathetic cardioneuropathy in dysautonomias. N Engl J Med 1997;336:696-702.
5. Goldstein DS, Holmes C, Li ST, et al. Cardiac sympathetic denervation in Parkinson disease. Ann Intern Med 2000;133:338-347.
6. Orimo S, Oka T, Miura H, et al. Sympathetic cardiac denervation in Parkinson's disease and pure autonomic failure but not in multiple system atrophy. J Neurol Neurosurg Psychiatry 2002;73: 776-777.
7. Orimo S, Ozawa E, Oka T, et al. Different histopathology accounting for a decrease in myocardial MIBG uptake in PD and MSA. Neurology 2001;57:1140-1141.
8. Wakabayashi K, Takahashi H. Neuropathology of autonomic nervous system in Parkinson's disease. Eur Neurol 1997;38 (Suppl 2):2-7.
9. Rajput AH, Rozdilsky B. Dysautonomia in Parkinsonism: a clinicopathological study. J Neurol Neurosurg Psychiatry 1976;39: 1092-1100.
10. Goldstein DS, Holmes C, Dendi R, et al. Orthostatic hypotension from sympathetic denervation in Parkinson's disease. Neurology 2002;58:1247-1255.
11. Goldstein DS, Eldadah BA, Holmes C, et al. Neurocirculatory abnormalities in Parkinson disease with orthostatic hypotension. Independence from levodopa treatment. Hypertension 2005;46: 1-7.
12. Sharabi Y, Eldadah B, Li ST, et al. Neuropharmacologic distinction of neurogenic orthostatic hypotension syndromes. Clin Neuropharmacol 2006;29:97-105.
13. Taki J, Nakajima K, Hwang EH, et al. Peripheral sympathetic dysfunction in patients with Parkinson's disease without autonomic failure is heart selective and disease specific. Eur J Nucl Med 2000;27:566-573.
14. Hirayama M, Hakusui S, Koike Y, et al. A scintigraphical qualitative analysis of peripheral vascular sympathetic function with meta-[123I]iodobenzylguanidine in neurological patients with autonomic failure. J Auton Nerv Syst 1995;53:230-234.
15. Goldstein DS, Horwitz D, Keiser HR. Comparison of techniques for measuring baroreflex sensitivity in man. Circulation 1982;66: 432-439.
16. Bianchetti MG, Minder I, Beretta-Piccoli C, et al. Effects of tyramine on blood pressure and plasma catecholamines in normal and hypertensive subjects. Klin Wochenschr 1982;60:465-470.
17. Jacob G, Costa F, Vincent S, et al. Neurovascular dissociation with paradoxical forearm vasodilation during systemic tyramine administration. Circulation 2003;107:2475-2479.
18. Jacob G, Gamboa A, Diedrich A, et al. Tyramine-induced vasodilation mediated by dopamine contamination: a paradox resolved. Hypertension 2005;46:355-359.
19. Charkoudian N, Joyner MJ, Sokolnicki LA, et al. Vascular adrenergic responsiveness is inversely related to tonic activity of sympathetic vasoconstrictor nerves in humans. J Physiol 2006; 572:821-827.
20. Meck JV, Martin DS, D'Aunno DS, Waters WW. Pressor response to intravenous tyramine is a marker of cardiac, but not vascular, adrenergic function. J Cardiovasc Pharmacol 2003;41: 126-131.
21. Goldstein DS, Zimlichman R, Stull R, Keiser HR. Plasma catecholamine and hemodynamic responses during isoproterenol infusions in humans. Clin Pharmacol Ther 1986;40:233-238.
22. Majewski H, Hedler L, Starke K. Evidence for a physiological role of presynaptic a-adrenoceptors: modulation of noradrenaline release in the pithed rabbit. Naunyn Schmiedeberg's Arch Pharmacol 1983;324:256-263.
23. Grossman E, Rea RF, Hoffman A, Goldstein DS. Yohimbine increases sympathetic nerve activity and norepinephrine spillover in normal volunteers. Am J Physiol 1991;260:R142-R147.
24. Cooper JA, Baratta F, Frieden J, Grossman J. Hemodynamic effects of edrophonium chloride (Tensilon) infusion. Chest 1975; 67:147-151.
25. Sharabi Y, Goldstein DS, Bentho O, et al. Sympathoadrenal function in patients with paroxysmal hypertension: pseudopheochromocytoma. J Hypertens 2007;25:2286-2295.
26. Sharabi Y, Zimlichman R, Alesci S, et al. Glucagon does not affect catecholamine release in primary cultures of bovine adrenal chromaffin cells. Horm Metab Res 2005;37:205-208.
27. Bruce S, Tack C, Patel JN, et al. Local sympathetic function in human skeletal muscle and adipose tissue assessed by microdialysis. Clin Auton Res 2002;12:13-19.
28. Holmes C, Eisenhofer G, Goldstein DS. Improved assay for plasma dihydroxyphenylacetic acid and other catechols using high-performance liquid chromatography with electrochemical detection. J Chromatog B Biomed Appl 1994;653:131-138.
29. Senard JM, Valet P, Durrieu G, et al. Adrenergic supersensitivity in parkinsonians with orthostatic hypotension. Eur J Clin Invest 1990;20:613-619.
30. Goldstein DS, Holmes C, Sharabi Y, et al. Plasma levels of catechols and metanephrines in neurogenic orthostatic hypotension. Neurology 2003;60:1327-1332.
31. Tipre DN, Goldstein DS. Cardiac and extra-cardiac sympathetic denervation in Parkinson disease with orthostatic hypotension and in pure autonomic failure. J Nucl Med 2005;46:1775-1781.
32. Matsui H, Udaka F, Oda M, et al. Metaiodobenzylguanidine (MIBG) uptake in Parkinson's disease also decreases at thyroid. Ann Nucl Med 2005;19:225-229.
33. Milon D, Allain H, Bentue-Ferrer D, et al. Cardiac β-adrenoceptor sensitivity and Parkinson's disease. Fundam Clin Pharmacol 1991;5:539-548.
34. Sharabi Y, Li ST, Dendi R, et al. Neurotransmitter specificity of sympathetic denervation in Parkinson's disease. Neurology 2003; 60:1036-1039.
35. Hague K, Lento P, Morgello S, et al. The distribution of Lewy bodies in pure autonomic failure: autopsy findings and review of the literature. Acta Neuropathol (Berl) 1997;94:192-196.
36. Amino T, Orimo S, Takahashi A, et al. Profound cardiac sympathetic denervation occurs in Parkinson disease. Brain Pathol 2005; 15:29-34.
37. Goldstein DS, Holmes C, Sato T, et al. Central dopamine deficiency in pure autonomic failure. Clin Auton Res 2008;18: 58-65.
38. Goldstein DS, Polinsky RJ, Garty M, et al. Patterns of plasma levels of catechols in neurogenic orthostatic hypotension. Ann Neurol 1989;26:558-563.
39. Polinsky RJ, Kopin IJ, Ebert MH, Weise V. Pharmacologic distinction of different orthostatic hypotension syndromes. Neurology 1981;31:1-7.
40. Raffel DM, Koeppe RA, Little R, et al. PET measurement of cardiac and nigrostriatal denervation in parkinsonian syndromes. J Nucl Med 2006;47:1769-1777.
41. Orimo S, Kanazawa T, Nakamura A, et al. Degeneration of cardiac sympathetic nerve can occur in multiple system atrophy. Acta Neuropathol (Berl) 2007;113:81-86.
42. Esler MD, Turner AG, Kaye DM, et al. Aging effects on human sympathetic neuronal function. AmJ Physiol 1995;268:R278-R285.
43. Seals DR, Esler MD. Human ageing and the sympathoadrenal system. J Physiol 2000;528:407-417.