Neurofibromatosis type 1 with external genitalia involvement. Presentation of 4 patients

Journal of Pediatric Surgery

Volumn 43, Issue 11, 2008, Pages 1998-2003

  Pascual Castroviejo, Ignacio ^a   Lopez Pereira, Pedro ^a   Savasta, Salvatore ^b   Lopez Gutierrez, Juan Carlos ^a   Lago, Carlos Míguelez ^c   Cisternino, Mariangela ^b  

^a HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^b FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^c HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

Author keywords

Bladder neurofibroma; Clitoromegaly; Labia majora neurofibroma; Neurofibromatosis type 1 (NF1); Penile neurofibroma; Plexiform neurofibroma; Pseudohermaphroditism

Indexed keywords

ARTICLE; BLADDER WALL; CASE REPORT; CHILD; CLINICAL FEATURE; CLITORIS; CORPUS CAVERNOSUM; FEMALE; GENITAL SYSTEM DISEASE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; NEUROFIBROMATOSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PENIS DISEASE; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PROSTATE;

CHILD; CHILD, PRESCHOOL; CLITORIS; CRYPTORCHIDISM; FEMALE; HUMANS; HYPERTROPHY; INFANT; MALE; NEUROFIBROMA, PLEXIFORM; NEUROFIBROMATOSIS 1; PELVIC NEOPLASMS; PENIS; URETERAL OBSTRUCTION; VULVAR NEOPLASMS;

EID: 55349114618     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2008.01.074     Document Type: Article

References (24)

1. Riccardi V.M. Neurofibromatosis vol 1 (1988), Karger, Basel 1-64
2. Huson S.M., Harper P.S., and Compston D.A.S. Von Recklinghausen neurofibromatosis. A Clinical and population study in south-east Wales. Brain 11 (1988) 1355-1381
3. Labardini M.M., Kallet H.A., and Cerny J.C. Urogenital neurofibromatosis simulating an intersex problem. J Urol 98 (1968) 627-632
4. Sutphen R., Galán-Gómez E., and Kousseff B.G. Clitoromegaly in neurofibromatosis. Am J Med Genet 55 (1995) 325-330
5. Barone J.G., Massad C.A., Parrott T.S., et al. Symptomatic tumors affecting the urinary tract in children with neurofibromatosis. J Urol 154 (1995) 1516-1517
6. Franceschini P., Silengo M., and Davi G.F. Pseudo-pseudohermaphroditism and multiple neurofibromatosis. J Urol 20 (1978) 388-389
7. Griebel M.L., Redman J.F., Kemp S.F., et al. Hypertrophy of clitoral hood: presenting sign of neurofibromatosis in female child. Urology 37 (1991) 337-339
8. Haddad H.M., and Jones Jr. H.W. Clitoral enlargement simulating pseudohermaphroditism. Am J Dis Child 99 (1960) 282-287
9. Haraoka M., Naito S., and Kumazawa J. Clitoral involvement by neurofibromatosis: a case report and review of the literature. J Urol 139 (1988) 95-96
10. Hoffman V.J. Die Neurofibromatose der Vulva unter dem Erscheinungsbild eines Pseudohermaphroditismus. Zentralbl Gynaekol 84 (1962) 961-966
11. Kaefer M., Adams M.C., and Rinck R.C. Principles in management of complex pediatric genitourinary plexiform neurofibroma. Urology 49 (1997) 936-940
12. Kearse Jr. W.S., and Ritchey M.L. Clitoral enlargement secondary to neurofibromatosis. Clin Pediatr 32 (1993) 303-304
13. Kenny F.M., Fetterman G.H., and Preeyasombat C. Neurofibromata simulating a penis and labioscrotal gonads in a girl with von Recklinghausen's disease. Pediatrics 37 (1966) 456-459
14. Messina A.M., and Strauss R.G. Pelvic neurofibromatosis. Obstet Gynecol 47 (1976) 635-665
15. Nogita T., Kawabata Y., Tsuchida T., et al. Clitoral and labial involvement of neurofibromatosis. J Am Acad Dermatol 23 (1990) 937-938
16. Nonomura K., Kanno T., Tanaka M., et al. A case of neurofibromatosis associated with clitoral enlargement and hypertension. J Pediatr Surg 27 (1992) 110-112
17. Rink R.C., and Mitchell M.E. Genitourinary neurofibromatosis in childhood. J Urol 130 (1983) 1176-1179
18. Schepel S.J., and Tolhurst D.E. Neurofibromata of clitoris and labium majus simulating a penis and testicle. Br J Plast Surg 34 (1981) 221-223
19. Thomas W.J., Bevan H.E., Hooper D.G., et al. Malignant schwannoma in the clitoris in a 1-year-old child. Cancer 63 (1989) 2216-2219
20. McDonnell C.H. Neurofibromatosis of the bladder and prostate. Amer J Surg 34 (1936) 90-93
21. Borden T.A., and Shrader D.A. Neurofibromatosis of bladder in a child: unusual cause of enuresis. Urology 15 (1980) 155-158
22. Fethiere W., Carter H.W., and Sturim H.S. Elephantiasis neuromatosa of the penis. Light and electron microscopical studies. Arch Pathol 97 (1974) 326-330
23. Thomson P.D., Harty J.I., and Koper D. Neurofibroma of the penis. Urology 40 (1992) 555-556
24. Ogawa A., and Watanabe K. Genitourinary neurofibromatosis in a child presenting with enlarged penis and scrotum. J Urol 135 (1986) 755-757