Serum parathyroid hormone levels predict falls in older adults with diabetes mellitus

Journal of the American Geriatrics Society

Volumn 56, Issue 11, 2008, Pages 2027-2032

  Houston, Denise K ^a,b   Schwartz, Ann V ^c   Cauley, Jane A ^d   Tylavsky, Frances A ^e   Simonsick, Eleanor M ^f   Harris, Tamara B ^f   De Rekeneire, Nathalie ^g   Schwartz, Gary G ^a   Kritchevsky, Stephen B ^b  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b WAKE FOREST UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^e UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^f NATIONAL INSTITUTE ON AGING   (United States)

^g NATIONAL CENTER FOR CHRONIC DISEASE PREVENTION AND HEALTH PROMOTION   (United States)

Author keywords

Falls; Physical performance; PTH

Indexed keywords

PARATHYROID HORMONE;

AGED; AGING; ALCOHOL CONSUMPTION; ARTICLE; BEHAVIOR; BODY COMPOSITION; BODY MASS; CONTROLLED STUDY; DIABETES MELLITUS; DRUG USE; FALL RISK ASSESSMENT; FALLING; FEMALE; HEALTH STATUS; HUMAN; HUMAN CELL; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PARATHYROID HORMONE BLOOD LEVEL; PHYSICAL ACTIVITY; PHYSICAL PERFORMANCE; SEASONAL VARIATION;

ACCIDENTAL FALLS; AGED; DIABETES MELLITUS; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; PARATHYROID HORMONE; PHYSICAL ENDURANCE; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; TIME FACTORS;

EID: 55349112528     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/j.1532-5415.2008.01966.x     Document Type: Article

References (41)

1. Tinetti ME. Clinical practice. Preventing falls in elderly persons. N Engl J Med 2003 348 : 42 49.
2. Kannus P, Sievanen H, Palvanen M et al. Prevention of falls and consequent injuries in elderly people. Lancet 2005 366 : 1885 1893.
3. Tinetti ME, Williams CS. Falls, injuries due to falls, and the risk of admission to a nursing home. N Engl J Med 1997 337 : 1279 1284.
4. Englander F, Hodson TJ, Terregrossa RA. Economic dimensions of slip and fall injuries. J Forensic Sci 1996 41 : 733 746.
5. Li F, Fisher KJ, Harmer P et al. Fear of falling in elderly persons: Association with falls, functional ability, and quality of life. J Gerontol B Psychol Sci Soc Sci 2003 58B : 283 290.
6. Schwartz AV, Hillier TA, Sellmeyer DE et al. Older women with diabetes have a higher risk of falls: A prospective study. Diabetes Care 2002 25 : 1749 1754.
7. Hanlon JT, Landerman LR, Fillenbaum GG et al. Falls in African American and white community-dwelling elderly residents. J Gerontol A Biol Sci Med Sci 2002 57A : M473 M478.
8. Volpato S, Leveille SG, Blaum C et al. Risk factors for falls in older disabled women with diabetes: The Women's Health and Aging Study. J Gerontol A Biol Sci Med Sci 2005 60A : 1539 1545.
9. Schwartz AV, Vittinghoff E, Sellmeyer DE et al. Diabetes-related complications, glycemic control, and falls in older adults. Diabetes Care 2008 31 : 391 396.
10. Stein MS, Wark JD, Scherer SC et al. Falls relate to vitamin D and parathyroid hormone in an Australian nursing home and hostel. J Am Geriatr Soc 1999 47 : 1195 1201.
11. Dhesi JK, Bearne LM, Moniz C et al. Neuromuscular and psychomotor function in elderly subjects who fall and the relationship with vitamin D status. J Bone Miner Res 2002 17 : 891 897.
12. Sambrook PN, Chen JS, March LM et al. Serum parathyroid hormone predicts time to fall independent of vitamin D status in a frail elderly population. J Clin Endocrinol Metab 2004 89 : 1572 1576.
13. Wat WZ, Leung JY, Tam S et al. Prevalence and impact of vitamin D insufficiency in southern Chinese adults. Ann Nutr Metab 2007 51 : 59 64.
14. McKenna MJ, Freaney R. Secondary hyperparathyroidism in the elderly: Means to defining hypovitaminosis D. Osteoporos Int 1998 8 (Suppl 2) : S3 S6.
15. Joborn C, Joborn H, Rastad J et al. Maximal isokinetic muscle strength in patients with primary hyperparathyroidism before and after parathyroid surgery. Br J Surg 1988 75 : 77 80.
16. Lips P. Vitamin D deficiency and secondary hyperparathyroidism in the elderly: Consequences for bone loss and fractures and therapeutic implications. Endocr Rev 2001 22 : 477 501.
17. Mosekilde L. Vitamin D and the elderly. Clin Endocrinol (Oxford) 2005 62 : 265 281.
18. Visser M, Deeg DJ, Lips P. Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): The Longitudinal Aging Study Amsterdam. J Clin Endocrinol Metab 2003 88 : 5766 5772.
19. Gerdhem P, Ringsberg KA, Obrant KJ et al. Association between 25-hydroxy vitamin D levels, physical activity, muscle strength and fractures in the prospective population-based OPRA Study of Elderly Women. Osteoporos Int 2005 16 : 1425 1431.
20. Verreault R, Semba RD, Volpato S et al. Low serum vitamin D does not predict new disability or loss of muscle strength in older women. J Am Geriatr Soc 2002 50 : 912 917.
21. Faulkner KA, Cauley JA, Zmuda JM et al. Higher 1,25-dihydroxyvitamin D3 concentrations associated with lower fall rates in older community-dwelling women. Osteoporos Int 2006 17 : 1318 1328.
22. Guralnik JM, Simonsick EM, Ferrucci L et al. A short physical performance battery assessing lower extremity function: Association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 1994 49 : M85 M94.
23. Simonsick EM, Newman AB, Nevitt MC et al. Measuring higher level physical function in well-functioning older adults: Expanding familiar approaches in the Health ABC Study. J Gerontol A Biol Sci Med Sci 2001 56A : M644 M649.
24. Teng EL, Chui HC. The Modified Mini-Mental State (3MS) Examination. J Clin Psychiatry 1987 48 : 314 318.
25. Radloff LS. The CES-D scale: A self-report depression scale for research in the general population. Appl Psychol Meas 1977 1 : 385 401.
26. Reichel H, Deibert B, Schmidt-Gayk H et al. Calcium metabolism in early chronic renal failure: Implications for the pathogenesis of hyperparathyroidism. Nephrol Dial Transplant 1991 6 : 162 169.
27. Coll E, Botey A, Alvarez L et al. Serum cystatin C as a new marker for noninvasive estimation of glomerular filtration rate and as a marker for early renal impairment. Am J Kidney Dis 2000 36 : 29 34.
28. Dharnidharka VR, Kwon C, Stevens G. Serum cystatin C is superior to serum creatinine as a marker of kidney function: A meta-analysis. Am J Kidney Dis 2002 40 : 221 226.
29. Erlandsen EJ, Randers E, Kristensen JH. Evaluation of the Dade Behring N Latex Cystatin C assay on the Dade Behring Nephelometer II system. Scand J Clin Lab Invest 1999 59 : 1 8.
30. Faulkner KA, Cauley JA, Zmuda JM et al. Ethnic differences in the frequency and circumstances of falling in older community-dwelling women. J Am Geriatr Soc 2005 53 : 1774 1779.
31. Means KM, O'Sullivan PS, Rodell DE. Balance, mobility, and falls among elderly African American women. Am J Phys Med Rehabil 2000 79 : 30 39.
32. Bell NH, Greene A, Epstein S et al. Evidence for alteration of the vitamin D-endocrine system in blacks. J Clin Invest 1985 76 : 470 473.
33. Fuleihan GE, Gundberg CM, Gleason R et al. Racial differences in parathyroid hormone dynamics. J Clin Endocrinol Metab 1994 79 : 1642 1647.
34. Kleerekoper M, Nelson DA, Peterson EL et al. Reference data for bone mass, calciotropic hormones, and biochemical markers of bone remodeling in older (55-75) postmenopausal white and black women. J Bone Miner Res 1994 9 : 1267 1276.
35. Harris SS. Vitamin D and African Americans. J Nutr 2006 136 : 1126 1129.
36. Cosman F, Nieves J, Dempster D et al. Vitamin D economy in blacks. J Bone Miner Res 2007 22 (Suppl 2) : V34 V38.
37. Cosman F, Morgan DC, Nieves JW et al. Resistance to bone resorbing effects of PTH in black women. J Bone Miner Res 1997 12 : 958 966.
38. Ganz DA, Higashi T, Rubenstein LZ. Monitoring falls in cohort studies of community-dwelling older people: Effect of the recall interval. J Am Geriatr Soc 2005 53 : 2190 2194.
39. Flicker L, Mead K, Macinnis RJ et al. Serum vitamin D and falls in older women in residential care in Australia. J Am Geriatr Soc 2003 51 : 1533 1538.
40. Snijder MB, van Schoor NM, Pluijm SM et al. Vitamin D status in relation to one-year risk of recurrent falling in older men and women. J Clin Endocrinol Metab 2006 91 : 2980 2985.
41. Pfeifer M, Begerow B, Minne HW. Vitamin D and muscle function. Osteoporos Int 2002 13 : 187 194.