Multiplex SNaPshot genotyping for detecting loss of heterozygosity in the mismatch-repair genes MLH1 and MSH2 in microsatellite-unstable tumors

Clinical Chemistry

Volumn 54, Issue 11, 2008, Pages 1844-1854

  Bujalkova, Maria ^a   Zavodna, Katarina ^a   Krivulcik, Tomas ^a   Ilencikova, Denisa ^a   Wolf, Brigitte ^b   Kovac, Michal ^a,c   Karner Hanusch, Judith ^b   Heinimann, Karl ^c   Marra, Giancarlo ^d   Jiricny, Josef ^d   Bartosova, Zdena ^a  

^a CANCER RESEARCH INSTITUTE   (Slovakia)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c UNIVERSITY OF BASEL   (Switzerland)

^d UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MUTL; SNARE PROTEIN;

ANALYZER; ARTICLE; BLOOD; CANCER PATIENT; CANCER SCREENING; CANCER STAGING; CANCER TISSUE; CAPILLARY ELECTROPHORESIS; CAUCASIAN; COLON CANCER; COLORECTAL CANCER; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC KIT; DNA DETERMINATION; DNA ISOLATION; DNA SEQUENCE; GENE; GENE FREQUENCY; GENE LOCATION; GENE MUTATION; GENOTYPE; GERM LINE; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; INFORMED CONSENT; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MLH1 GENE; MSH2 GENE; MULTIPLEX POLYMERASE CHAIN REACTION; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BASE PAIR MISMATCH; BASE SEQUENCE; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA PRIMERS; DNA REPAIR; GENOTYPE; HUMANS; LOSS OF HETEROZYGOSITY; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; SENSITIVITY AND SPECIFICITY;

EID: 55349101227     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2008.108902     Document Type: Article

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