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Volumn 68, Issue 15, 2008, Pages 1615-1623

Intracellular death platform steps-in: Targeting prostate tumors via endoplasmic reticulum (ER) apoptosis

Author keywords

Apoptosis; BCL 2 family; ESR; Prostate cancer; UPR

Indexed keywords

ANDROGEN; CALCIUM; PROTEIN BCL 2;

EID: 55249125058     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.20828     Document Type: Review
Times cited : (18)

References (88)
  • 4
    • 0037213862 scopus 로고    scopus 로고
    • Metastatic carcinoma of the prostate: Identifying prognostic groups using recursive partitioning
    • Glass TR, Tangen CM, Crawford ED, Thompson I. Metastatic carcinoma of the prostate: Identifying prognostic groups using recursive partitioning. J Urol 2003;169(1):164-169.
    • (2003) J Urol , vol.169 , Issue.1 , pp. 164-169
    • Glass, T.R.1    Tangen, C.M.2    Crawford, E.D.3    Thompson, I.4
  • 6
    • 0036598992 scopus 로고    scopus 로고
    • Targeting death and decoy receptors of the tumour-necrosis factor superfamily
    • Ashkenazi A. Targeting death and decoy receptors of the tumour-necrosis factor superfamily. Nat Rev Cancer 2002;2(6):420-430.
    • (2002) Nat Rev Cancer , vol.2 , Issue.6 , pp. 420-430
    • Ashkenazi, A.1
  • 8
    • 0042335762 scopus 로고    scopus 로고
    • Ceramide-mediated clustering is required for CD95-DISC formation
    • Grassme H, Cremesti A, Kolesnick R, Gulbins E. Ceramide-mediated clustering is required for CD95-DISC formation. Oncogene 2003;22(35):5457-5470.
    • (2003) Oncogene , vol.22 , Issue.35 , pp. 5457-5470
    • Grassme, H.1    Cremesti, A.2    Kolesnick, R.3    Gulbins, E.4
  • 9
    • 0037276437 scopus 로고    scopus 로고
    • The CD95(APO-1/Fas) DISC and beyond
    • Peter ME, Krammer PH. The CD95(APO-1/Fas) DISC and beyond. Cell Death Differ 2003;10(1):26-35.
    • (2003) Cell Death Differ , vol.10 , Issue.1 , pp. 26-35
    • Peter, M.E.1    Krammer, P.H.2
  • 11
    • 0033667778 scopus 로고    scopus 로고
    • FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
    • Sprick M, Weigand MA, Rieser E, Rauch CT, Juo P, Blenis J, Krammer PH, Walczak H. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 2000;12:599-609.
    • (2000) Immunity , vol.12 , pp. 599-609
    • Sprick, M.1    Weigand, M.A.2    Rieser, E.3    Rauch, C.T.4    Juo, P.5    Blenis, J.6    Krammer, P.H.7    Walczak, H.8
  • 13
    • 0033662433 scopus 로고    scopus 로고
    • Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
    • Kischkel F, Lawrence DA, Chuntharapai A, Schow P, Kim KJ, Ashkenazi A. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 2000;12:611-620.
    • (2000) Immunity , vol.12 , pp. 611-620
    • Kischkel, F.1    Lawrence, D.A.2    Chuntharapai, A.3    Schow, P.4    Kim, K.J.5    Ashkenazi, A.6
  • 14
    • 0028883850 scopus 로고
    • Cytotoxicity-dependent APO-1, (Fas/CD95)-associated proteins from a death-inducing signaling complex (DISC) with the receptor
    • Kischkel F, Helbardt S, Behrmann I, Germer M, Pawlita M, Kramer PH, Peter ME. Cytotoxicity-dependent APO-1, (Fas/CD95)-associated proteins from a death-inducing signaling complex (DISC) with the receptor. EMBO J 1995;14:5579-5588.
    • (1995) EMBO J , vol.14 , pp. 5579-5588
    • Kischkel, F.1    Helbardt, S.2    Behrmann, I.3    Germer, M.4    Pawlita, M.5    Kramer, P.H.6    Peter, M.E.7
  • 17
    • 85120146715 scopus 로고    scopus 로고
    • Kim HE, Jiang X, Du F, Wang X, PHAPI, CAS, and Hsp70 promote apoptosome formation by preventing Apaf-1 aggregation and enhancing nucleotide exchange on Apaf-1. Mol Cell 2008;30(2):239-247.
    • Kim HE, Jiang X, Du F, Wang X, PHAPI, CAS, and Hsp70 promote apoptosome formation by preventing Apaf-1 aggregation and enhancing nucleotide exchange on Apaf-1. Mol Cell 2008;30(2):239-247.
  • 18
    • 0034616945 scopus 로고    scopus 로고
    • Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000;102:33-42.
    • Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000;102:33-42.
  • 20
    • 0021821903 scopus 로고
    • Involvement of the bcl-2 gene in human follicular lymphoma
    • Tsujimoto Y, Cossman J, Jaffe E, Croce CM. Involvement of the bcl-2 gene in human follicular lymphoma. Science 1985;228:1440-1443.
    • (1985) Science , vol.228 , pp. 1440-1443
    • Tsujimoto, Y.1    Cossman, J.2    Jaffe, E.3    Croce, C.M.4
  • 21
    • 0024454762 scopus 로고
    • Stress-resistance conferred by high level of bcl-2alpha protein in human B lypmphoblastoid cell
    • Tsujimoto Y. Stress-resistance conferred by high level of bcl-2alpha protein in human B lypmphoblastoid cell. Oncogene 1989;4:1331-1336.
    • (1989) Oncogene , vol.4 , pp. 1331-1336
    • Tsujimoto, Y.1
  • 22
    • 0023786047 scopus 로고    scopus 로고
    • bcl-2 gene promotes haematopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
    • Vaux D, Cory S, Adams JM. bcl-2 gene promotes haematopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 1998;335:440-442.
    • (1998) Nature , vol.335 , pp. 440-442
    • Vaux, D.1    Cory, S.2    Adams, J.M.3
  • 23
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • Veis D, Sorenson CM, Shutter JR, Korsmeyer SJ. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 1993;75:229-240.
    • (1993) Cell , vol.75 , pp. 229-240
    • Veis, D.1    Sorenson, C.M.2    Shutter, J.R.3    Korsmeyer, S.J.4
  • 24
    • 0028175759 scopus 로고
    • Targeted disruption of Bcl-2alpha-beta in mice: Occurrence of gray hair, polycystic kidney disease, and lymphocytopenia
    • Nakayama K, Negishi I, Kuida K, Sawa H, Loh DY. Targeted disruption of Bcl-2alpha-beta in mice: Occurrence of gray hair, polycystic kidney disease, and lymphocytopenia. Proc Natl Acad Sci USA 1994;91:3700-3704.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3700-3704
    • Nakayama, K.1    Negishi, I.2    Kuida, K.3    Sawa, H.4    Loh, D.Y.5
  • 25
    • 0028833859 scopus 로고
    • Bcl-2 deficiency in mice leads to pleiotropic abnormalities: Accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine
    • Kamada S, Shimono A, Shinto Y, Tsujimura T, Takahashi T, Noda T, Kitamura Y, Kondoh H, Tsujimoto Y. Bcl-2 deficiency in mice leads to pleiotropic abnormalities: Accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine. Caner Res 1995;55:354-359.
    • (1995) Caner Res , vol.55 , pp. 354-359
    • Kamada, S.1    Shimono, A.2    Shinto, Y.3    Tsujimura, T.4    Takahashi, T.5    Noda, T.6    Kitamura, Y.7    Kondoh, H.8    Tsujimoto, Y.9
  • 28
    • 0033562966 scopus 로고    scopus 로고
    • Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls
    • Kaufman RJ. Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls. Genes Dev 1999;13(10):1211-1233.
    • (1999) Genes Dev , vol.13 , Issue.10 , pp. 1211-1233
    • Kaufman, R.J.1
  • 29
    • 1842843860 scopus 로고    scopus 로고
    • Coupling endoplasmic reticulum stress to the cell death program
    • Rao RV, Ellerby HM, Bredesen DE. Coupling endoplasmic reticulum stress to the cell death program. Cell Death Differ 2004;11(4):372-380.
    • (2004) Cell Death Differ , vol.11 , Issue.4 , pp. 372-380
    • Rao, R.V.1    Ellerby, H.M.2    Bredesen, D.E.3
  • 30
    • 0034716887 scopus 로고    scopus 로고
    • Tripartite management of unfolded proteins in the endoplasmic reticulum
    • Mori K. Tripartite management of unfolded proteins in the endoplasmic reticulum. Cell 2000;101(5):451-454.
    • (2000) Cell , vol.101 , Issue.5 , pp. 451-454
    • Mori, K.1
  • 31
    • 22244446505 scopus 로고    scopus 로고
    • The mammalian unfolded protein response
    • Schroder M, Kaufman RJ. The mammalian unfolded protein response. Annu Rev Biochem 2005;74:739-789.
    • (2005) Annu Rev Biochem , vol.74 , pp. 739-789
    • Schroder, M.1    Kaufman, R.J.2
  • 32
    • 10444226462 scopus 로고    scopus 로고
    • ER stress and the unfolded protein response
    • Schroder M, Kaufman RJ. ER stress and the unfolded protein response. Mutat Res 2005;569(1-2):29-63.
    • (2005) Mutat Res , vol.569 , Issue.1-2 , pp. 29-63
    • Schroder, M.1    Kaufman, R.J.2
  • 33
    • 0031960313 scopus 로고    scopus 로고
    • A tool coming of age: Thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPases
    • Treiman M, Caspersen C, Christensen SB. A tool coming of age: Thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPases. Trends Pharmacol Sci 1998;19(4):131-135.
    • (1998) Trends Pharmacol Sci , vol.19 , Issue.4 , pp. 131-135
    • Treiman, M.1    Caspersen, C.2    Christensen, S.B.3
  • 34
    • 0020028654 scopus 로고
    • Relationship of the structure and biological activity of the natural homologues of tunicamycin
    • Duksin D, Mahoney WC. Relationship of the structure and biological activity of the natural homologues of tunicamycin. J Biol Chem 1982;257(6):3105-3109.
    • (1982) J Biol Chem , vol.257 , Issue.6 , pp. 3105-3109
    • Duksin, D.1    Mahoney, W.C.2
  • 35
    • 0347285295 scopus 로고    scopus 로고
    • A trip to the ER: Coping with stress
    • Rutkowski DT, Kaufman RJ. A trip to the ER: Coping with stress. Trends Cell Biol 2004;14(1):20-28.
    • (2004) Trends Cell Biol , vol.14 , Issue.1 , pp. 20-28
    • Rutkowski, D.T.1    Kaufman, R.J.2
  • 36
    • 0036702298 scopus 로고    scopus 로고
    • ER-associated degradation in protein quality control and cellular regulation
    • Hampton RY. ER-associated degradation in protein quality control and cellular regulation. Curr Opin Cell Biol 2002;14(4):476-482.
    • (2002) Curr Opin Cell Biol , vol.14 , Issue.4 , pp. 476-482
    • Hampton, R.Y.1
  • 37
    • 0037287977 scopus 로고    scopus 로고
    • Endoplasmic reticulum-associated protein degradation
    • Jarosch E, Lenk U, Sommer T. Endoplasmic reticulum-associated protein degradation. Int Rev Cytol 2003;223:39-81.
    • (2003) Int Rev Cytol , vol.223 , pp. 39-81
    • Jarosch, E.1    Lenk, U.2    Sommer, T.3
  • 38
    • 0033168382 scopus 로고    scopus 로고
    • Retrograde protein translocation: ERADication of secretory proteins in health and disease
    • Plemper RK, Wolf DH. Retrograde protein translocation: ERADication of secretory proteins in health and disease. Trends Biochem Sci 1999;24(7):266-270.
    • (1999) Trends Biochem Sci , vol.24 , Issue.7 , pp. 266-270
    • Plemper, R.K.1    Wolf, D.H.2
  • 39
    • 0036270698 scopus 로고    scopus 로고
    • Retro-translocation of proteins from the endoplasmic reticulum into the cytosol
    • Tsai B, Ye Y, Rapoport TA. Retro-translocation of proteins from the endoplasmic reticulum into the cytosol. Nat Rev Mol Cell Biol 2002;3(4):246-255.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , Issue.4 , pp. 246-255
    • Tsai, B.1    Ye, Y.2    Rapoport, T.A.3
  • 40
    • 0031961688 scopus 로고    scopus 로고
    • Regulation of translational initiation during cellular responses to stress
    • Brostrom CO, Brostrom MA. Regulation of translational initiation during cellular responses to stress. Prog Nucleic Acid Res Mol Biol 1998;58:79-125.
    • (1998) Prog Nucleic Acid Res Mol Biol , vol.58 , pp. 79-125
    • Brostrom, C.O.1    Brostrom, M.A.2
  • 41
    • 0036437307 scopus 로고    scopus 로고
    • Transcriptional and, translational control in the Mammalian unfolded protein response
    • Harding HP, Calf on M, Urano F, Novoa I, Ron D. Transcriptional and, translational control in the Mammalian unfolded protein response. Annu Rev Cell Dev Biol 2002;18:575-599.
    • (2002) Annu Rev Cell Dev Biol , vol.18 , pp. 575-599
    • Harding, H.P.1    Calf on, M.2    Urano, F.3    Novoa, I.4    Ron, D.5
  • 42
    • 0027324844 scopus 로고
    • Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase
    • Cox JS, Shamu CE, Walter P. Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell 1993;73(6):1197-1206.
    • (1993) Cell , vol.73 , Issue.6 , pp. 1197-1206
    • Cox, J.S.1    Shamu, C.E.2    Walter, P.3
  • 43
    • 0027305620 scopus 로고
    • A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus
    • Mori K, Ma W, Gething MJ, Sambrook J. A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell 1993;74(4):743-756.
    • (1993) Cell , vol.74 , Issue.4 , pp. 743-756
    • Mori, K.1    Ma, W.2    Gething, M.J.3    Sambrook, J.4
  • 44
    • 0029903049 scopus 로고    scopus 로고
    • Oligomerization and phosphorylation of the Irelp kinase during intracellular signaling from the endoplasmic reticulum to the nucleus
    • Shamu CE, Walter P. Oligomerization and phosphorylation of the Irelp kinase during intracellular signaling from the endoplasmic reticulum to the nucleus. EMBO J 1996;15(12):3028-3039.
    • (1996) EMBO J , vol.15 , Issue.12 , pp. 3028-3039
    • Shamu, C.E.1    Walter, P.2
  • 45
    • 0029892851 scopus 로고    scopus 로고
    • The unfolded protein response pathway in Saccharomyces cerevisiae. Oligomerization and trans-phosphorylation of Irelp (Ernlp) are required for kinase activation
    • Welihinda AA, Kaufman RJ. The unfolded protein response pathway in Saccharomyces cerevisiae. Oligomerization and trans-phosphorylation of Irelp (Ernlp) are required for kinase activation. J Biol Chem 1996;271(30):18181- 18187.
    • (1996) J Biol Chem , vol.271 , Issue.30 , pp. 18181-18187
    • Welihinda, A.A.1    Kaufman, R.J.2
  • 46
    • 0030954870 scopus 로고    scopus 로고
    • The transmembrane kinase Irelp is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response
    • Sidrauski C, Walter P. The transmembrane kinase Irelp is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell 1997;90(6):1031-1039.
    • (1997) Cell , vol.90 , Issue.6 , pp. 1031-1039
    • Sidrauski, C.1    Walter, P.2
  • 47
    • 0030808558 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Haclp/Ern4p that activates the unfolded protein response
    • Kawahara T, Yanagi H, Yura T, Mori K. Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Haclp/Ern4p that activates the unfolded protein response. Mol Biol Cell 1997;8(10):1845-1862.
    • (1997) Mol Biol Cell , vol.8 , Issue.10 , pp. 1845-1862
    • Kawahara, T.1    Yanagi, H.2    Yura, T.3    Mori, K.4
  • 48
    • 0030228708 scopus 로고    scopus 로고
    • Signalling from endoplasmic reticulum to nucleus: Transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway
    • Mori K, Kawahara T, Yoshida H, Yanagi H, Yura T. Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway. Genes Cells 1996;1(9):803-817.
    • (1996) Genes Cells , vol.1 , Issue.9 , pp. 803-817
    • Mori, K.1    Kawahara, T.2    Yoshida, H.3    Yanagi, H.4    Yura, T.5
  • 49
    • 33751159209 scopus 로고    scopus 로고
    • Intracellular signaling by the unfolded protein response
    • Bernales S, Papa ER, Walter P. Intracellular signaling by the unfolded protein response. Annu Rev Cell Dev Biol 2006;22:487-508.
    • (2006) Annu Rev Cell Dev Biol , vol.22 , pp. 487-508
    • Bernales, S.1    Papa, E.R.2    Walter, P.3
  • 50
    • 33745606008 scopus 로고    scopus 로고
    • Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in
    • PLoS Genet
    • Shen X, Ellis RE, Sakaki K, Kaufman RJ. Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. PLoS Genet 2005;1(3):e37.
    • (2005) C. elegans , vol.1 , Issue.3
    • Shen, X.1    Ellis, R.E.2    Sakaki, K.3    Kaufman, R.J.4
  • 51
    • 33745893809 scopus 로고    scopus 로고
    • Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
    • Hollien J, Weissman JS. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 2006;313(5783):104-107.
    • (2006) Science , vol.313 , Issue.5783 , pp. 104-107
    • Hollien, J.1    Weissman, J.S.2
  • 53
    • 0037083755 scopus 로고    scopus 로고
    • IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
    • Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, Kaufman RJ. IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev 2002;16(4):452-466.
    • (2002) Genes Dev , vol.16 , Issue.4 , pp. 452-466
    • Lee, K.1    Tirasophon, W.2    Shen, X.3    Michalak, M.4    Prywes, R.5    Okada, T.6    Yoshida, H.7    Mori, K.8    Kaufman, R.J.9
  • 54
    • 0035966269 scopus 로고    scopus 로고
    • XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
    • Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 2001;107(7):881-891.
    • (2001) Cell , vol.107 , Issue.7 , pp. 881-891
    • Yoshida, H.1    Matsui, T.2    Yamamoto, A.3    Okada, T.4    Mori, K.5
  • 55
    • 34548172495 scopus 로고    scopus 로고
    • Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1
    • Yamamoto K, Sato T, Matsui T, Sato M, Okada T, Yoshida H, Harada A, Mori K. Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1. Dev Cell 2007;13(3):365-376.
    • (2007) Dev Cell , vol.13 , Issue.3 , pp. 365-376
    • Yamamoto, K.1    Sato, T.2    Matsui, T.3    Sato, M.4    Okada, T.5    Yoshida, H.6    Harada, A.7    Mori, K.8
  • 56
    • 0036069980 scopus 로고    scopus 로고
    • ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals
    • Shen J, Chen X, Hendershot L, Prywes R. ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals. Dev Cell 2002;3(1):99-111.
    • (2002) Dev Cell , vol.3 , Issue.1 , pp. 99-111
    • Shen, J.1    Chen, X.2    Hendershot, L.3    Prywes, R.4
  • 58
    • 0142059951 scopus 로고    scopus 로고
    • XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response
    • Lee AH, Iwakoshi NN, Glimcher LH. XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol Cell Biol 2003;23(21):7448-7459.
    • (2003) Mol Cell Biol , vol.23 , Issue.21 , pp. 7448-7459
    • Lee, A.H.1    Iwakoshi, N.N.2    Glimcher, L.H.3
  • 59
    • 0033634641 scopus 로고    scopus 로고
    • Perk is essential for translational regulation and cell survival during the unfolded protein response
    • Harding HP, Zhang Y, Bertolotti A, Zeng H, Ron D. Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell 2000;5(5):897-904.
    • (2000) Mol Cell , vol.5 , Issue.5 , pp. 897-904
    • Harding, H.P.1    Zhang, Y.2    Bertolotti, A.3    Zeng, H.4    Ron, D.5
  • 60
    • 0033590451 scopus 로고    scopus 로고
    • Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
    • Harding HP, Zhang Y, Ron D. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 1999;397(6716):271-274.
    • (1999) Nature , vol.397 , Issue.6716 , pp. 271-274
    • Harding, H.P.1    Zhang, Y.2    Ron, D.3
  • 61
    • 0031755020 scopus 로고    scopus 로고
    • Identification and, characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control
    • Shi Y, Vattem KM, Sood R, An J, Liang J, Stramm L, Wek RC. Identification and, characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control. Mol Cell Biol 1998;18(12):7499-7509.
    • (1998) Mol Cell Biol , vol.18 , Issue.12 , pp. 7499-7509
    • Shi, Y.1    Vattem, K.M.2    Sood, R.3    An, J.4    Liang, J.5    Stramm, L.6    Wek, R.C.7
  • 62
    • 0033739622 scopus 로고    scopus 로고
    • PERK mediates cell-cycle exit during the mammalian unfolded protein response
    • Brewer JW, Diehl JA. PERK mediates cell-cycle exit during the mammalian unfolded protein response. Proc Natl Acad Sci USA 2000;97(23):12625-12630.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.23 , pp. 12625-12630
    • Brewer, J.W.1    Diehl, J.A.2
  • 63
    • 0033782015 scopus 로고    scopus 로고
    • Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
    • Bertolotti A, Zhang Y, Hendershot LM, Harding HP, Ron D. Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat Cell Biol 2000;2(6):326-332.
    • (2000) Nat Cell Biol , vol.2 , Issue.6 , pp. 326-332
    • Bertolotti, A.1    Zhang, Y.2    Hendershot, L.M.3    Harding, H.P.4    Ron, D.5
  • 65
    • 0035736259 scopus 로고    scopus 로고
    • Organelle-specific initiation of cell death pathways
    • Ferri KF, Kroemer G. Organelle-specific initiation of cell death pathways. Nat Cell Biol 2001;3(11):E255-263.
    • (2001) Nat Cell Biol , vol.3 , Issue.11
    • Ferri, K.F.1    Kroemer, G.2
  • 66
    • 0034973982 scopus 로고    scopus 로고
    • Scheuner D, Song B, McEwen E, Liu C, Laybutt R, Gillespie P, Saunders T, Bonner-Weir S, Kaufman RJ. Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol Cell 2001;7(6):1 165-1176.
    • Scheuner D, Song B, McEwen E, Liu C, Laybutt R, Gillespie P, Saunders T, Bonner-Weir S, Kaufman RJ. Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol Cell 2001;7(6):1 165-1176.
  • 68
    • 0035144493 scopus 로고    scopus 로고
    • Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bc12 and perturbing the cellular redox state
    • McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bc12 and perturbing the cellular redox state. Mol Cell Biol 2001;21(4):1249-1259.
    • (2001) Mol Cell Biol , vol.21 , Issue.4 , pp. 1249-1259
    • McCullough, K.D.1    Martindale, J.L.2    Klotz, L.O.3    Aw, T.Y.4    Holbrook, N.J.5
  • 69
    • 8544283103 scopus 로고    scopus 로고
    • CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells
    • Yamaguchi H, Wang HG. CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells. J Biol Chem 2004;279(44):45495-45502.
    • (2004) J Biol Chem , vol.279 , Issue.44 , pp. 45495-45502
    • Yamaguchi, H.1    Wang, H.G.2
  • 70
    • 0041703031 scopus 로고    scopus 로고
    • The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: Elucidation by GADD34-deficient mice
    • Kojima E, Takeuchi A, Haneda M, Yagi A, Hasegawa T, Yamaki K, Takeda K, Akira S, Shimokata K, Isobe K. The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: Elucidation by GADD34-deficient mice. FASEB J 2003;17(11):1573-1575.
    • (2003) FASEB J , vol.17 , Issue.11 , pp. 1573-1575
    • Kojima, E.1    Takeuchi, A.2    Haneda, M.3    Yagi, A.4    Hasegawa, T.5    Yamaki, K.6    Takeda, K.7    Akira, S.8    Shimokata, K.9    Isobe, K.10
  • 72
    • 0037416211 scopus 로고    scopus 로고
    • Stress-induced gene expression requires programmed recovery from translational repression
    • Novoa I, Zhang Y, Zeng H, Jungreis R, Harding HP, Ron D. Stress-induced gene expression requires programmed recovery from translational repression. EMBO J 2003;22(5):1180-1187.
    • (2003) EMBO J , vol.22 , Issue.5 , pp. 1180-1187
    • Novoa, I.1    Zhang, Y.2    Zeng, H.3    Jungreis, R.4    Harding, H.P.5    Ron, D.6
  • 73
    • 0345599024 scopus 로고    scopus 로고
    • Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells
    • Jousse C, Oyadomari S, Novoa I, Lu P, Zhang Y, Harding HP, Ron D. Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells. J Cell Biol 2003;163(4):767-775.
    • (2003) J Cell Biol , vol.163 , Issue.4 , pp. 767-775
    • Jousse, C.1    Oyadomari, S.2    Novoa, I.3    Lu, P.4    Zhang, Y.5    Harding, H.P.6    Ron, D.7
  • 75
    • 0036606540 scopus 로고    scopus 로고
    • ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
    • Nishitoh H, Matsuzawa A, Tobiume K, Saegusa K, Takeda K, Inoue K, Hori S, Kakizuka A, Ichijo H. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev 2002;16(11):1345-1355.
    • (2002) Genes Dev , vol.16 , Issue.11 , pp. 1345-1355
    • Nishitoh, H.1    Matsuzawa, A.2    Tobiume, K.3    Saegusa, K.4    Takeda, K.5    Inoue, K.6    Hori, S.7    Kakizuka, A.8    Ichijo, H.9
  • 81
    • 0043133837 scopus 로고    scopus 로고
    • Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-KB in response to diverse cellular stresses
    • Jiang H, Wek SA, McGrath BC, Scheuner D, Kaufman RJ, Cavener DR, Wek RC. Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-KB in response to diverse cellular stresses. Mol Cell Biol 2003;25:5651-5663.
    • (2003) Mol Cell Biol , vol.25 , pp. 5651-5663
    • Jiang, H.1    Wek, S.A.2    McGrath, B.C.3    Scheuner, D.4    Kaufman, R.J.5    Cavener, D.R.6    Wek, R.C.7
  • 82
    • 33645815074 scopus 로고    scopus 로고
    • Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1 alpha-mediated NF-KB activation and down-regulation of TRAF2 expression
    • Hu P, Han Z, Couvillon AD, Kaufman RJ, Exton JH. Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1 alpha-mediated NF-KB activation and down-regulation of TRAF2 expression. Mol Cell Biol 2006;26:3071-3084.
    • (2006) Mol Cell Biol , vol.26 , pp. 3071-3084
    • Hu, P.1    Han, Z.2    Couvillon, A.D.3    Kaufman, R.J.4    Exton, J.H.5
  • 83
    • 0035957929 scopus 로고    scopus 로고
    • Activation of caspase-12, an endoplasmic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress
    • Yoneda T, Imaizumi K, Oono K, Yui D, Gomi F, Katayama T, Tohyama M. Activation of caspase-12, an endoplasmic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J Biol Chem 2001;276:13940-13935.
    • (2001) J Biol Chem , vol.276 , pp. 13940-13935
    • Yoneda, T.1    Imaizumi, K.2    Oono, K.3    Yui, D.4    Gomi, F.5    Katayama, T.6    Tohyama, M.7
  • 85
    • 23844481790 scopus 로고    scopus 로고
    • Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis
    • Obeng EA, Boise LH. Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis. J Biol Chem 2005;280(33):29578-29587.
    • (2005) J Biol Chem , vol.280 , Issue.33 , pp. 29578-29587
    • Obeng, E.A.1    Boise, L.H.2
  • 86
    • 24644432531 scopus 로고    scopus 로고
    • The SERCA pump as a therapeutic target: Making a "smart bomb" for prostate cancer
    • Denmeade SR, Isaacs JT. The SERCA pump as a therapeutic target: making a "smart bomb" for prostate cancer. Cancer Biol Ther 2005;4(1):14-22.
    • (2005) Cancer Biol Ther , vol.4 , Issue.1 , pp. 14-22
    • Denmeade, S.R.1    Isaacs, J.T.2
  • 87
    • 0037385313 scopus 로고    scopus 로고
    • Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1
    • Iwakoshi NN, Lee AH, Vallabhajosyula P, Otipoby KL, Rajewsky K, Glimcher LH. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat Immunol 2003;4(4):321 -329.
    • (2003) Nat Immunol , vol.4 , Issue.4 , pp. 321-329
    • Iwakoshi, N.N.1    Lee, A.H.2    Vallabhajosyula, P.3    Otipoby, K.L.4    Rajewsky, K.5    Glimcher, L.H.6
  • 88
    • 31544446659 scopus 로고    scopus 로고
    • Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway
    • Garrison JB, Kyprianou N. Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway. Cancer Res 2006;66(1):464-472.
    • (2006) Cancer Res , vol.66 , Issue.1 , pp. 464-472
    • Garrison, J.B.1    Kyprianou, N.2


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