Differential distribution of the sodium-vitamin C cotransporter-1 along the proximal tubule of the mouse and human kidney

Kidney International

Volumn 74, Issue 10, 2008, Pages 1278-1286

  Castro, Tamara ^a   Low, Marcela ^a   Salazar, Katterine ^a   Montecinos, Hernán ^a   Cifuentes, Manuel ^b   Yáñez, Alejandro J ^c   Slebe, Juan Carlos ^c   Figueroa, Carlos D ^c   Reinicke, Karin ^a   De Los Angeles García, María ^a   Henriquez, Juan Pablo ^a   Nualart, Francisco ^a  

^a UNIVERSITY OF CONCEPCIÓN   (Chile)

^b UNIVERSITY OF MÁLAGA   (Spain)

^c UNIVERSIDAD AUSTRAL DE CHILE   (Chile)

Author keywords

FBPase; Immunohistochemistry; PHA lectin; Proximal tubule; SVCT1; Vitamin C

Indexed keywords

ASCORBIC ACID; COTRANSPORTER; SODIUM; SODIUM VITAMIN C COTRANSPORTER 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; IMMUNOHISTOCHEMISTRY; KIDNEY PROXIMAL TUBULE; MALE; MOUSE; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; TEMPERATURE SENSITIVITY;

ABSORPTION; ANIMALS; ASCORBIC ACID; HUMANS; HYDROGEN-ION CONCENTRATION; INTESTINES; KIDNEY TUBULES, PROXIMAL; KINETICS; LIVER; MICE; RNA, MESSENGER; SODIUM; SYMPORTERS; TEMPERATURE;

EID: 55249117705     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2008.329     Document Type: Article

References (30)

1. Englard S, Seifter S. The biochemical functions of ascorbic acid. Annu Rev Nutr 1986; 6: 365-406.
2. Fraga CG, Motchnik PA, Shigenaga MK et al. Ascorbic acid protects against endogenous oxidative DNA damage in human sperm. Proc Natl Acad Sci USA 1991; 88: 11003-11006.
3. Mellors AJ, Nahrwold DL, Rose RC. Ascorbic acid flux across mucosal border of guinea pig and human ileum. Am J Physiol 1977; 233: E374-E379.
4. Siliprandi L, Vanni P, Kessler M et al. Na+-dependent, electroneutral L-ascorbate transport across brush border membrane vesicles from guinea pig small intestine. Biochim Biophys Acta 1979; 552: 129-142.
5. Faaland CA, Race JE, Ricken G et al. Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase transporters. Biochim Biophys Acta 1998; 1442: 353-360.
6. Daruwala R, Song J, Koh WS et al. Cloning and functional characterization of the human sodium-dependent vitamin C transporters hSVCT1 and hSVCT2. FEBS Lett 1999; 460: 480-484.
7. Rajan DP, Huang W, Dutta B et al. Human placental sodium-dependent vitamin C transporter (SVCT2): molecular cloning and transport function. Biochem Biophys Res Commun 1999; 262: 762-768.
8. Tsukaguchi H, Tokui T, Mackenzie B et al. A family of mammalian Na+-dependent L-ascorbic acid transporters. Nature 1999; 399: 70-75.
9. Wang H, Dutta B, Huang W et al. Human Na(+)-dependent vitamin C transporter 1 (hSVCT1): primary structure, functional characteristics and evidence for a non-functional splice variant. Biochim Biophys Acta 1999; 1461: 1-9.
10. Wang Y, Mackenzie B, Tsukaguchi H et al. Human vitamin C (L-ascorbic acid) transporter SVCT1. Biochem Biophys Res Commun 2000; 267: 488-494.
11. Castro M, Caprile T, Astuya A et al. High-affinity sodium-vitamin C co-transporters (SVCT) expression in embryonic mouse neurons. J Neurochem 2001; 78: 815-823.
12. Castro MA, Pozo M, Cortes C et al. Intracellular ascorbic acid inhibits transport of glucose by neurons, but not by astrocytes. J Neurochem 2007; 102: 773-782.
13. Astuya A, Caprile T, Castro M et al. Vitamin C uptake and recycling among normal and tumor cells from the central nervous system. J Neurosci Res 2005; 79: 146-156.
14. Best KA, Holmes ME, Samson SE et al. Ascorbate uptake in pig coronary artery endothelial cells. Mol Cell Biochem 2005; 271: 43-49.
15. Toggenburger G, Hausermann M, Mutsch B et al. Na+-dependent, potential-sensitive L-ascorbate transport across brush border membrane vesicles from kidney cortex. Biochim Biophys Acta 1981; 646: 433-443.
16. Bianchi J, Rose RC. Na+-independent dehydro-L-ascorbic acid uptake in renal brush-border membrane vesicles. Biochim Biophys Acta 1985; 819: 75-82.
17. Boyer JC, Campbell CE, Sigurdson WJ et al. Polarized localization of vitamin C transporters, SVCT1 and SVCT2, in epithelial cells. Biochem Biophys Res Commun 2005; 334: 150-156.
18. Lee JH, Oh CS, Mun GH et al. Immunohistochemical localization of sodium-dependent L-ascorbic acid transporter 1 protein in rat kidney. Histochem Cell Biol 2006; 126: 491-494.
19. Kriz W, Bankir L. A standard nomenclature for structures of the kidney. The Renal Commission of the International Union of Physiological Sciences (IUPS). Kidney Int 1988; 33: 1-7.
20. Maulen NP, Henriquez EA, Kempe S et al. Up-regulation and polarized expression of the sodium-ascorbic acid transporter SVCT1 in post-confluent differentiated CaCo-2 cells. J Biol Chem 2003; 278: 9035-9041.
21. MacDonald L, Thumser AE, Sharp P. Decreased expression of the vitamin C transporter SVCT1 by ascorbic acid in a human intestinal epithelial cell line. Br J Nutr 2002; 87: 97-100.
22. Johnston L, Laverty G. Vitamin C transport and SVCT1 transporter expression in chick renal proximal tubule cells in culture. Comp Biochem Physiol A Mol Integr Physiol 2007; 146: 327-334.
23. Liang WJ, Johnson D, Ma LS et al. Regulation of the human vitamin C transporters expressed in COS-1 cells by protein kinase C (corrected). Am J Physiol Cell Physiol 2002; 283: C1696-C1704.
24. Rose RC. Ascorbic acid transport in mammalian kidney. Am J Physiol 1986; 250: F627-F632.
25. Nualart F, Hein S, Rodriguez EM et al. Identification and partial characterization of the secretory glycoproteins of the bovine subcommissural organ-Reissner's fiber complex. Evidence for the existence of two precursor forms. Brain Res Mol Brain Res 1991; 11: 227-238.
26. Poblete MT, Nualart F, del Pozo M et al. Alpha 1-antitrypsin expression in human thyroid papillary carcinoma. Am J Surg Pathol 1996; 20: 956-963.
27. Peruzzo B, Pastor FE, Blazquez JL et al. A second look at the barriers of the medial basal hypothalamus. Exp Brain Res 2000; 132: 10-26.
28. Nualart F, Godoy A, Reinicke K. Expression of the hexose transporters GLUT1 and GLUT2 during the early development of the human brain. Brain Res 1999; 824: 97-104.
29. Garcia Mde L, Salazar K, Millan C et al. Sodium vitamin C cotransporter SVCT2 is expressed in hypothalamic glial cells. Glia 2005; 50: 32-47.
30. Zamora-Leon SP, Golde DW, Concha II et al. Expression of the fructose transporter GLUT5 in human breast cancer. Proc Natl Acad Sci USA 1996; 93: 1847-1852.