Regioselective synthesis of N-aminoisoindolones and mono-N- and di-N,N′-substituted phthalazones utilizing hydrazine nucleophiles in a palladium-catalyzed three-component cascade process

Journal of Organic Chemistry

Volumn 73, Issue 21, 2008, Pages 8352-8356

  Grigg, Ronald ^a   Sridharan, Visuvanathar ^a   Shah, Mufakhrul ^a   Mutton, Simon ^a   Kilner, Colin ^a   MacPherson, David ^b   Milner, Peter ^b  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONYLATION; CHEMICAL REACTIONS; HYDRAZINE; NUCLEOPHILES; PALLADIUM;

CASCADE PROCESSES; CHEMICAL EQUATIONS; DISUBSTITUTED HYDRAZINES; INTRAMOLECULAR MICHAEL ADDITIONS; REGIOSELECTIVE SYNTHESES; SYNTHESIS OF;

SYNTHESIS (CHEMICAL);

HYDRAZINE; IODINE DERIVATIVE; ISOINDOLE DERIVATIVE; PALLADIUM; PHTHALAZINE DERIVATIVE;

AMINATION; ARTICLE; CARBONYLATION; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; DRUG SYNTHESIS; MICHAEL ADDITION; RING CLOSING METATHESIS;

CATALYSIS; HYDRAZINES; ISOINDOLES; PALLADIUM; PHTHALAZINES;

EID: 55249103848     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo800822p     Document Type: Article

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