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Volumn 9, Issue 15, 2008, Pages 2727-2731

Is rimonabant efficacious and safe in the treatment of obesity?

Author keywords

Atherosclerosis; Clinical trials; Obesity; Rimonabant; RIO; STRADIVARIUS; Weight loss

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTICOAGULANT AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CLOPIDOGREL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ORAL ANTIDIABETIC AGENT; PLACEBO; RIMONABANT; TICLOPIDINE;

EID: 55249102956     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.9.15.2727     Document Type: Article
Times cited : (25)

References (13)
  • 1
    • 0037422846 scopus 로고    scopus 로고
    • Obesity in adulthood and its consequences for life expectancy: A life-table analysis
    • Peters A, Barendregt JJ, Willenkens F, et al. Obesity in adulthood and its consequences for life expectancy: a life-table analysis. Ann Intern Med 2003;138:24-32
    • (2003) Ann Intern Med , vol.138 , pp. 24-32
    • Peters, A.1    Barendregt, J.J.2    Willenkens, F.3
  • 2
    • 17844388556 scopus 로고    scopus 로고
    • Endocannabinoid control of food intake and energy balance
    • Di Marzo V, Matias I. Endocannabinoid control of food intake and energy balance. Nat Neurosci 2005;8:585-9
    • (2005) Nat Neurosci , vol.8 , pp. 585-589
    • Di Marzo, V.1    Matias, I.2
  • 3
    • 17144382751 scopus 로고    scopus 로고
    • Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
    • for the RIO-Europe Study Group
    • Van Gaal LF, Rissanen AM, Ziegler O, for the RIO-Europe Study Group. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 2005;365:1388-97
    • (2005) Lancet , vol.365 , pp. 1388-1397
    • Van Gaal, L.F.1    Rissanen, A.M.2    Ziegler, O.3
  • 4
    • 32644441249 scopus 로고    scopus 로고
    • Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: A Randomized Controlled Trial
    • for the RIO-North America Study Group
    • Pi-Sunyer FX, Aronne LJ, Heshmati HM, et al. for the RIO-North America Study Group. Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: A Randomized Controlled Trial. JAMA 2006;295:761-75
    • (2006) JAMA , vol.295 , pp. 761-775
    • Pi-Sunyer, F.X.1    Aronne, L.J.2    Heshmati, H.M.3
  • 5
    • 27844463517 scopus 로고    scopus 로고
    • Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
    • for the Rimonabant in Obesity-Lipids Study Group
    • Deprés JP, Golay A, Sjöstóm L, for the Rimonabant in Obesity-Lipids Study Group. Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia. N Engl J Med 2005;353:2121-34
    • (2005) N Engl J Med , vol.353 , pp. 2121-2134
    • Deprés, J.P.1    Golay, A.2    Sjöstóm, L.3
  • 6
    • 33751001942 scopus 로고    scopus 로고
    • Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: A randomised controlled study
    • For the RIO-Diabetes Study Group
    • Scheen AJ, Finer N, Hollander P, et al. For the RIO-Diabetes Study Group. Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study. Lancet 2006;368:1660-72
    • (2006) Lancet , vol.368 , pp. 1660-1672
    • Scheen, A.J.1    Finer, N.2    Hollander, P.3
  • 7
    • 36048995288 scopus 로고    scopus 로고
    • Efficacy and safety of the weight-loss drug rimonabant: A meta-analysis of randomised trials
    • Christensen R, Kristensen PK, Bartels EM, et al. Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials. Lancet 2007;370:1706-43
    • (2007) Lancet , vol.370 , pp. 1706-1743
    • Christensen, R.1    Kristensen, P.K.2    Bartels, E.M.3
  • 8
    • 55249083070 scopus 로고    scopus 로고
    • FDA Briefing Document
    • and Drug Administration Advisory Committee, 13 June 2007 Available from:, Accessed on 7th July 2008
    • US Food and Drug Administration Advisory Committee. FDA Briefing Document. NDA 21-888 Zimulti (rimonabant) Tablets, 20 mg Sanofi Aventis Advisory Committee - 13 June 2007 Available from: www.fda.gov/ohrms/ dockets/ac/07/briefing/2007-4306b1-fda-backgrounder.pdf [Accessed on 7th July 2008]
    • Zimulti (rimonabant) Tablets, 20 mg Sanofi Aventis Advisory Committee , vol.NDA 21-888
    • Food, U.S.1
  • 9
    • 41149130137 scopus 로고    scopus 로고
    • Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in overweight/obese patients: Pooled 1-year data from the Rimonabant in Obesity (RIO) program
    • Van Gaal L, Pi-Sunyer X, Deprés JP, et al. Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in overweight/obese patients: pooled 1-year data from the Rimonabant in Obesity (RIO) program. Diabetes Care 2008;31(Suppl 2):S229-40
    • (2008) Diabetes Care , vol.31 , Issue.SUPPL. 2
    • Van Gaal, L.1    Pi-Sunyer, X.2    Deprés, J.P.3
  • 10
    • 41649090426 scopus 로고    scopus 로고
    • Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease - the STRADIVARIUS randomized controlled trial
    • Nissen SE, Nicholls SJ, Wolski K, et al. Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease - the STRADIVARIUS randomized controlled trial. JAMA 2008;299:1547-60
    • (2008) JAMA , vol.299 , pp. 1547-1560
    • Nissen, S.E.1    Nicholls, S.J.2    Wolski, K.3
  • 11
    • 34249333702 scopus 로고    scopus 로고
    • Columbia Classification Algorithm of Suicide Assessment (C-CASA): Classification of suicidal events in the FDA's paediatric suicidal risk analysis of antidepressants
    • Posner K, Oquendo MA, Gould M, et al. Columbia Classification Algorithm of Suicide Assessment (C-CASA): classification of suicidal events in the FDA's paediatric suicidal risk analysis of antidepressants. Am J Psychiatry 2007;164:1035-43
    • (2007) Am J Psychiatry , vol.164 , pp. 1035-1043
    • Posner, K.1    Oquendo, M.A.2    Gould, M.3
  • 12
    • 55249093180 scopus 로고    scopus 로고
    • Atherosclerosis underlying development assessed by intima-media thickness in patients on rimonabant. Available from:, Accessed on 7th July 2008
    • Atherosclerosis underlying development assessed by intima-media thickness in patients on rimonabant. Available from: http://clinicaltrials.gov/ct2/show/NCT00228176 [Accessed on 7th July 2008]


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.