A Myo6 mutation destroys coordination between the myosin heads, revealing new functions of myosin VI in the stereocilia of mammalian inner ear hair cells

PLoS Genetics

Volumn 4, Issue 10, 2008, Pages

  Hertzano, Ronna ^a,g   Shalit, Ella ^a   Rzadzinska, Agnieszka K ^b   Dror, Amiel A ^a   Song, Lin ^c   Ron, Uri ^a   Tan, Joshua T ^d   Shitrit, Alina Starovolsky ^a   Fuchs, Helmut ^e   Hasson, Tama ^d,h   Ben Tal, Nir ^a   Sweeney, H Lee ^c   De Angelis, Martin Hrabe ^e,f   Steel, Karen P ^b   Avraham, Karen B ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e INSTITUTE OF EPIDEMIOLOGY   (Germany)

^f TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^g UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; MYOSIN; MYOSIN VI; ADENOSINE TRIPHOSPHATASE; MYOSIN HEAVY CHAIN;

ACTIN FILAMENT; ANIMAL EXPERIMENT; ARTICLE; CAENORHABDITIS ELEGANS; CHROMOSOME 9; CONTROLLED STUDY; GENE LOSS; GENE MAPPING; GENE MUTATION; GENE STRUCTURE; HAIR CELL; INNER EAR; MAMMAL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; STEREOCILIUM; ANIMAL; C3H MOUSE; C57BL MOUSE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; CHROMOSOME MAP; FEMALE; GENETICS; HEARING IMPAIRMENT; HUMAN; MALE; METABOLISM; MISSENSE MUTATION; MOUSE MUTANT; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; TRANSPORT VESICLE;

CAENORHABDITIS ELEGANS; MAMMALIA; MUS;

ADENOSINE TRIPHOSPHATASES; ANIMALS; CELL LINE; CHROMOSOME MAPPING; DEAFNESS; FEMALE; HAIR CELLS, AUDITORY, INNER; HUMANS; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, MOLECULAR; MUTATION, MISSENSE; MYOSIN HEAVY CHAINS; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; TRANSPORT VESICLES;

EID: 55249098639     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000207     Document Type: Article

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