메뉴 건너뛰기




Volumn 44, Issue 17, 2008, Pages 2689-2695

Epigenetic events in normal colonic mucosa surrounding colorectal cancer lesions

Author keywords

Colorectal cancer; Epigenetic events; Field cancerisation; Normal colonic tissue

Indexed keywords

B RAF KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; K RAS PROTEIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; ONCOPROTEIN; PROTEIN MLH1; PROTEIN P53; UVOMORULIN;

EID: 55249093832     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2008.09.004     Document Type: Article
Times cited : (32)

References (36)
  • 1
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon E.R., and Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 61 5 (1990) 759-767
    • (1990) Cell , vol.61 , Issue.5 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 3
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler K.W., and Vogelstein B. Lessons from hereditary colorectal cancer. Cell 87 2 (1996) 159-170
    • (1996) Cell , vol.87 , Issue.2 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 4
    • 33745824650 scopus 로고    scopus 로고
    • Influence of methylated p15 and p16 genes on clinicopathological features in colorectal cancer
    • Ishiguro A., Takahata T., Saito M., Yoshiya G., Tamura Y., Sasaki M., et al. Influence of methylated p15 and p16 genes on clinicopathological features in colorectal cancer. J Gastroenterol Hepatol 21 8 (2006) 1334-1339
    • (2006) J Gastroenterol Hepatol , vol.21 , Issue.8 , pp. 1334-1339
    • Ishiguro, A.1    Takahata, T.2    Saito, M.3    Yoshiya, G.4    Tamura, Y.5    Sasaki, M.6
  • 5
    • 33644875316 scopus 로고    scopus 로고
    • CpG island methylation as an early event during adenoma progression in carcinogenesis of sporadic colorectal cancer
    • Kim H.C., Roh S.A., Ga I.H., Kim J.S., Yu C.S., and Kim J.C. CpG island methylation as an early event during adenoma progression in carcinogenesis of sporadic colorectal cancer. J Gastroenterol Hepatol 20 12 (2005) 1920-1926
    • (2005) J Gastroenterol Hepatol , vol.20 , Issue.12 , pp. 1920-1926
    • Kim, H.C.1    Roh, S.A.2    Ga, I.H.3    Kim, J.S.4    Yu, C.S.5    Kim, J.C.6
  • 6
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer C., Kinzler K.W., and Vogelstein B. Genetic instabilities in human cancers. Nature 396 6712 (1998) 643-649
    • (1998) Nature , vol.396 , Issue.6712 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 7
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones P.A., and Baylin S.B. The fundamental role of epigenetic events in cancer. Nat Rev Genet 3 6 (2002) 415-428
    • (2002) Nat Rev Genet , vol.3 , Issue.6 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 8
    • 0033229890 scopus 로고    scopus 로고
    • Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype
    • Toyota M., Ahuja N., Suzuki H., Itoh F., Ohe-Toyota M., Imai K., et al. Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype. Cancer Res 59 21 (1999) 5438-5442
    • (1999) Cancer Res , vol.59 , Issue.21 , pp. 5438-5442
    • Toyota, M.1    Ahuja, N.2    Suzuki, H.3    Itoh, F.4    Ohe-Toyota, M.5    Imai, K.6
  • 9
    • 0034681117 scopus 로고    scopus 로고
    • Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype
    • Toyota M., Ohe-Toyota M., Ahuja N., and Issa J.P. Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype. Proc Natl Acad Sci USA 97 2 (2000) 710-715
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.2 , pp. 710-715
    • Toyota, M.1    Ohe-Toyota, M.2    Ahuja, N.3    Issa, J.P.4
  • 10
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • Jones P.A., and Laird P.W. Cancer epigenetics comes of age. Nat Genet 21 2 (1999) 163-167
    • (1999) Nat Genet , vol.21 , Issue.2 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 11
    • 0034662626 scopus 로고    scopus 로고
    • Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer
    • Esteller M., Sparks A., Toyota M., Sanchez-Cespedes M., Capella G., Peinado M.A., et al. Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer. Cancer Res 60 16 (2000) 4366-4371
    • (2000) Cancer Res , vol.60 , Issue.16 , pp. 4366-4371
    • Esteller, M.1    Sparks, A.2    Toyota, M.3    Sanchez-Cespedes, M.4    Capella, G.5    Peinado, M.A.6
  • 12
    • 0035899946 scopus 로고    scopus 로고
    • Bethesda guidelines: relation to microsatellite instability and MLH1 promoter methylation in patients with colorectal cancer
    • Raedle J., Trojan J., Brieger A., Weber N., Schafer D., Plotz G., et al. Bethesda guidelines: relation to microsatellite instability and MLH1 promoter methylation in patients with colorectal cancer. Ann Intern Med 135 8 Pt 1 (2001) 566-576
    • (2001) Ann Intern Med , vol.135 , Issue.8 PART 1 , pp. 566-576
    • Raedle, J.1    Trojan, J.2    Brieger, A.3    Weber, N.4    Schafer, D.5    Plotz, G.6
  • 13
    • 33646497449 scopus 로고    scopus 로고
    • Prognostic value of p16INK4a and p14ARF gene hypermethylation in human colon cancer
    • Lee M., Sup Han W., Kyoung Kim O., Hee Sung S., Sun Cho M., Lee S.N., et al. Prognostic value of p16INK4a and p14ARF gene hypermethylation in human colon cancer. Pathol Res Pract 202 6 (2006) 415-424
    • (2006) Pathol Res Pract , vol.202 , Issue.6 , pp. 415-424
    • Lee, M.1    Sup Han, W.2    Kyoung Kim, O.3    Hee Sung, S.4    Sun Cho, M.5    Lee, S.N.6
  • 14
    • 36749025213 scopus 로고    scopus 로고
    • Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer
    • Shen L., Toyota M., Kondo Y., Lin E., Zhang L., Guo Y., et al. Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer. Proc Natl Acad Sci USA 104 47 (2007) 18654-18659
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.47 , pp. 18654-18659
    • Shen, L.1    Toyota, M.2    Kondo, Y.3    Lin, E.4    Zhang, L.5    Guo, Y.6
  • 15
    • 33344467235 scopus 로고    scopus 로고
    • DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer
    • Kawakami K., Ruszkiewicz A., Bennett G., Moore J., Grieu F., Watanabe G., et al. DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer. Brit J Cancer 94 4 (2006) 593-598
    • (2006) Brit J Cancer , vol.94 , Issue.4 , pp. 593-598
    • Kawakami, K.1    Ruszkiewicz, A.2    Bennett, G.3    Moore, J.4    Grieu, F.5    Watanabe, G.6
  • 16
    • 33748528622 scopus 로고    scopus 로고
    • Promoter methylation status of the MGMT, hMLH1, and CDKN2A/p16 genes in non-neoplastic mucosa of patients with and without colorectal adenomas
    • Ye C., Shrubsole M.J., Cai Q., Ness R., Grady W.M., Smalley W., et al. Promoter methylation status of the MGMT, hMLH1, and CDKN2A/p16 genes in non-neoplastic mucosa of patients with and without colorectal adenomas. Oncol Rep 16 2 (2006) 429-435
    • (2006) Oncol Rep , vol.16 , Issue.2 , pp. 429-435
    • Ye, C.1    Shrubsole, M.J.2    Cai, Q.3    Ness, R.4    Grady, W.M.5    Smalley, W.6
  • 17
    • 0032148387 scopus 로고    scopus 로고
    • Hypermethylation of the p16INK4a promoter in colectomy specimens of patients with long-standing and extensive ulcerative colitis
    • Hsieh C.J., Klump B., Holzmann K., Borchard F., Gregor M., and Porschen R. Hypermethylation of the p16INK4a promoter in colectomy specimens of patients with long-standing and extensive ulcerative colitis. Cancer Res 58 17 (1998) 3942-3945
    • (1998) Cancer Res , vol.58 , Issue.17 , pp. 3942-3945
    • Hsieh, C.J.1    Klump, B.2    Holzmann, K.3    Borchard, F.4    Gregor, M.5    Porschen, R.6
  • 18
    • 0035328527 scopus 로고    scopus 로고
    • Accelerated age-related CpG island methylation in ulcerative colitis
    • Issa J.P., Ahuja N., Toyota M., Bronner M.P., and Brentnall T.A. Accelerated age-related CpG island methylation in ulcerative colitis. Cancer Res 61 9 (2001) 3573-3577
    • (2001) Cancer Res , vol.61 , Issue.9 , pp. 3573-3577
    • Issa, J.P.1    Ahuja, N.2    Toyota, M.3    Bronner, M.P.4    Brentnall, T.A.5
  • 20
    • 78651056338 scopus 로고
    • Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin
    • Slaughter D.P., Southwick H.W., and Smejkal W. Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer 6 5 (1953) 963-968
    • (1953) Cancer , vol.6 , Issue.5 , pp. 963-968
    • Slaughter, D.P.1    Southwick, H.W.2    Smejkal, W.3
  • 21
    • 13244264729 scopus 로고    scopus 로고
    • Progressive methylation during the serrated neoplasia pathway of the colorectum
    • Dong S.M., Lee E.J., Jeon E.S., Park C.K., and Kim K.M. Progressive methylation during the serrated neoplasia pathway of the colorectum. Mod Pathol 18 2 (2005) 170-178
    • (2005) Mod Pathol , vol.18 , Issue.2 , pp. 170-178
    • Dong, S.M.1    Lee, E.J.2    Jeon, E.S.3    Park, C.K.4    Kim, K.M.5
  • 22
    • 33750532320 scopus 로고    scopus 로고
    • Relationship between point gene mutation, chromosomal abnormality, and tumour suppressor gene methylation status in colorectal adenomas
    • Judson H., Stewart A., Leslie A., Pratt N.R., Baty D.U., Steele R.J., et al. Relationship between point gene mutation, chromosomal abnormality, and tumour suppressor gene methylation status in colorectal adenomas. J Pathol 210 3 (2006) 344-350
    • (2006) J Pathol , vol.210 , Issue.3 , pp. 344-350
    • Judson, H.1    Stewart, A.2    Leslie, A.3    Pratt, N.R.4    Baty, D.U.5    Steele, R.J.6
  • 23
    • 1642535480 scopus 로고    scopus 로고
    • BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer
    • Deng G., Bell I., Crawley S., Gum J., Terdiman J.P., Allen B.A., et al. BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer. Clin Cancer Res 10 1 (2004) 191-195
    • (2004) Clin Cancer Res , vol.10 , Issue.1 , pp. 191-195
    • Deng, G.1    Bell, I.2    Crawley, S.3    Gum, J.4    Terdiman, J.P.5    Allen, B.A.6
  • 26
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman J.G., and Baylin S.B. Gene silencing in cancer in association with promoter hypermethylation. New Engl J Med 349 21 (2003) 2042-2054
    • (2003) New Engl J Med , vol.349 , Issue.21 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 27
    • 0031284676 scopus 로고    scopus 로고
    • Low O6-alkylguanine DNA-alkyltransferase activity in normal colorectal tissue is associated with colorectal tumours containing a GC → AT transition in the K-ras oncogene
    • Jackson P.E., Hall C.N., O'Connor P.J., Cooper D.P., Margison G.P., and Povey A.C. Low O6-alkylguanine DNA-alkyltransferase activity in normal colorectal tissue is associated with colorectal tumours containing a GC → AT transition in the K-ras oncogene. Carcinogenesis 18 7 (1997) 1299-1302
    • (1997) Carcinogenesis , vol.18 , Issue.7 , pp. 1299-1302
    • Jackson, P.E.1    Hall, C.N.2    O'Connor, P.J.3    Cooper, D.P.4    Margison, G.P.5    Povey, A.C.6
  • 28
    • 19244370208 scopus 로고    scopus 로고
    • Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis
    • Esteller M., Toyota M., Sanchez-Cespedes M., Capella G., Peinado M.A., Watkins D.N., et al. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis. Cancer Res 60 9 (2000) 2368-2371
    • (2000) Cancer Res , vol.60 , Issue.9 , pp. 2368-2371
    • Esteller, M.1    Toyota, M.2    Sanchez-Cespedes, M.3    Capella, G.4    Peinado, M.A.5    Watkins, D.N.6
  • 30
    • 0027371264 scopus 로고
    • Immunohistochemical analysis of E-cadherin expression in human colorectal tumours
    • Van Aken J., Cuvelier C.A., De Wever N., Roels J., Gao Y., and Mareel M.M. Immunohistochemical analysis of E-cadherin expression in human colorectal tumours. Pathol Res Pract 189 9 (1993) 975-978
    • (1993) Pathol Res Pract , vol.189 , Issue.9 , pp. 975-978
    • Van Aken, J.1    Cuvelier, C.A.2    De Wever, N.3    Roels, J.4    Gao, Y.5    Mareel, M.M.6
  • 31
    • 33748040054 scopus 로고    scopus 로고
    • Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma
    • Ogino S., Odze R.D., Kawasaki T., Brahmandam M., Kirkner G.J., Laird P.W., et al. Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma. Am J Surg Pathol 30 9 (2006) 1175-1183
    • (2006) Am J Surg Pathol , vol.30 , Issue.9 , pp. 1175-1183
    • Ogino, S.1    Odze, R.D.2    Kawasaki, T.3    Brahmandam, M.4    Kirkner, G.J.5    Laird, P.W.6
  • 32
    • 0034771582 scopus 로고    scopus 로고
    • p16 gene methylation in colorectal cancers associated with Duke's staging
    • Yi J., Wang Z.W., Cang H., Chen Y.Y., Zhao R., Yu B.M., et al. p16 gene methylation in colorectal cancers associated with Duke's staging. World J Gastroenterol 7 5 (2001) 722-725
    • (2001) World J Gastroenterol , vol.7 , Issue.5 , pp. 722-725
    • Yi, J.1    Wang, Z.W.2    Cang, H.3    Chen, Y.Y.4    Zhao, R.5    Yu, B.M.6
  • 33
    • 21444449914 scopus 로고    scopus 로고
    • Methylation and expression of p16INK4 tumor suppressor gene in primary colorectal cancer tissues
    • Kim B.N., Yamamoto H., Ikeda K., Damdinsuren B., Sugita Y., Ngan C.Y., et al. Methylation and expression of p16INK4 tumor suppressor gene in primary colorectal cancer tissues. Int J Oncol 26 5 (2005) 1217-1226
    • (2005) Int J Oncol , vol.26 , Issue.5 , pp. 1217-1226
    • Kim, B.N.1    Yamamoto, H.2    Ikeda, K.3    Damdinsuren, B.4    Sugita, Y.5    Ngan, C.Y.6
  • 34
    • 55249109649 scopus 로고    scopus 로고
    • Press release: change in gene may be underlying molecular defect in some colorectal cancers, study suggests
    • Zielinski S.L. Press release: change in gene may be underlying molecular defect in some colorectal cancers, study suggests. J Natl Cancer Inst 97 18 (2005) 1315
    • (2005) J Natl Cancer Inst , vol.97 , Issue.18 , pp. 1315
    • Zielinski, S.L.1
  • 35
    • 25144474539 scopus 로고    scopus 로고
    • DNA methylation, field effects, and colorectal cancer
    • Giovannucci E., and Ogino S. DNA methylation, field effects, and colorectal cancer. J Natl Cancer Inst 97 18 (2005) 1317-1319
    • (2005) J Natl Cancer Inst , vol.97 , Issue.18 , pp. 1317-1319
    • Giovannucci, E.1    Ogino, S.2
  • 36
    • 33644825262 scopus 로고    scopus 로고
    • Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage
    • Suzuki K., Suzuki I., Leodolter A., Alonso S., Horiuchi S., Yamashita K., et al. Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage. Cancer Cell 9 3 (2006) 199-207
    • (2006) Cancer Cell , vol.9 , Issue.3 , pp. 199-207
    • Suzuki, K.1    Suzuki, I.2    Leodolter, A.3    Alonso, S.4    Horiuchi, S.5    Yamashita, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.