The 3,4-oxide is responsible for the DNA binding of benzo[ghi]perylene, a polycyclic aromatic hydrocarbon without a "classic" bay-region

Chemico-Biological Interactions

Volumn 176, Issue 2-3, 2008, Pages 179-187

  Platt, Karl L ^a   Grupe, Stefanie ^a   Fickler, Michael ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

32P postlabeling; Bay region; Benzo ghi perylene; DNA binding; K region epoxide; Polycyclic aromatic hydrocarbons

Indexed keywords

3,4 EPOXY 3,4 DIHYDROBENZO[GHI]PERYLENE; 3,4,11,12 BISEPOXY 3,4,11,12 TETRAHYDROBENZO[GHI]PERYLENE; BENZO[GHI]PERYLENE; DNA; EPOXIDE; EPOXIDE HYDROLASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DNA ADDUCT; DNA BINDING; ENZYME ACTIVATION; GENOTOXICITY; MALE; MUTAGENICITY; NONHUMAN; RAT; SALMONELLA TYPHIMURIUM;

ANIMALS; BINDING SITES; CATTLE; DNA; EPOXIDE HYDROLASES; MALE; MICROSOMES; MOLECULAR STRUCTURE; MUTAGENESIS; MUTAGENICITY TESTS; PERYLENE; RATS; RATS, SPRAGUE-DAWLEY;

BACTERIA (MICROORGANISMS); SALMONELLA TYPHIMURIUM;

EID: 55249087155     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2008.07.010     Document Type: Article

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