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Volumn 15, Issue 11, 2008, Pages 2296-2297

Translation initiation factor 4E (eIF4E): Prognostic marker and potential therapeutic target

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR 2; INITIATION FACTOR 4E; PROTEIN KINASE B; RAPAMYCIN; TEMSIROLIMUS;

EID: 55149115382     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-008-0116-7     Document Type: Editorial
Times cited : (8)

References (13)
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  • 2
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    • Translation factor eIF4E rescues cells from Myc-dependent apoptosis by inhibiting cytochrome c release
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  • 3
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    • Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology
    • A De Benedetti RE Rhoads 1990 Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology Proc Natl Acad Sci USA 87 8212 6
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8212-6
    • De Benedetti, A.1    Rhoads, R.E.2
  • 4
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    • Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
    • DC Fingar S Salama C Tsou 2002 Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E Genes Dev 16 1472 87
    • (2002) Genes Dev , vol.16 , pp. 1472-87
    • Fingar, D.C.1    Salama, S.2    Tsou, C.3
  • 5
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    • A prospective trial on initiation factor 4E (eIF4E) overexpression and cancer recurrence in node-negative breast cancer
    • (in press)
    • Holm N, Byrnes K, Johnson L, et al. A prospective trial on initiation factor 4E (eIF4E) overexpression and cancer recurrence in node-negative breast cancer. Ann Surg Oncol. (in press)
    • Ann Surg Oncol
    • Holm, N.1    Byrnes, K.2    Johnson, L.3
  • 6
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    • Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors
    • O Larsson S Li OA Issaenko 2007 Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors Cancer Res 67 6814 24
    • (2007) Cancer Res , vol.67 , pp. 6814-24
    • Larsson, O.1    Li, S.2    Issaenko, O.A.3
  • 7
    • 33746206552 scopus 로고    scopus 로고
    • High eIF4E, VEGF, and microvessel density in stage I to III breast cancer
    • discussion 691-2
    • K Byrnes S White Q Chu 2006 High eIF4E, VEGF, and microvessel density in stage I to III breast cancer Ann Surg 243 684 90 discussion 691-2
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  • 8
    • 0030940199 scopus 로고    scopus 로고
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    • BD Li L Liu M Dawson 1997 Overexpression of eukaryotic initiation factor 4E (eIF4E) in breast carcinoma Cancer 79 2385 90
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    • Li, B.D.1    Liu, L.2    Dawson, M.3
  • 9
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    • Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity
    • JR Graff BW Konicek TM Vincent 2007 Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity J Clin Invest 117 2638 48
    • (2007) J Clin Invest , vol.117 , pp. 2638-48
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  • 10
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    • EIF4E knockdown decreases breast cancer cell growth without activating Akt signaling
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    • The eIF4E RNA regulon promotes the Akt signaling pathway
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  • 12
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  • 13
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.