Second cancers in children treated with modern radiotherapy techniques

Radiotherapy and Oncology

Volumn 89, Issue 2, 2008, Pages 135-140

  Schneider, Uwe ^a   Lomax, Antony ^b   Timmermann, Beate ^b  

^a TRIEMLI HOSPITAL   (Switzerland)

^b PAUL SCHERRER INSTITUTE   (Switzerland)

Author keywords

Children; IMRT; Organ equivalent dose; Proton radiotherapy; Secondary cancer

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BLADDER; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER RISK; CASE REPORT; COMPUTER ASSISTED RADIOTHERAPY; CONTROLLED STUDY; DOSE RESPONSE; HUMAN; INTENSITY MODULATED RADIATION THERAPY; MALE; PHOTON THERAPY; PRIORITY JOURNAL; PROSTATE CANCER; PROTON THERAPY; RADIATION DOSE; RADIATION DOSE DISTRIBUTION; RECTUM; RHABDOMYOSARCOMA; SECOND CANCER; TREATMENT PLANNING;

DOSE FRACTIONATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; INFANT; MALE; MIDDLE AGED; NEOPLASMS, RADIATION-INDUCED; PROSTATIC NEOPLASMS; RADIATION DOSAGE; RADIOTHERAPY; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RECTUM; RHABDOMYOSARCOMA; RISK ASSESSMENT; SCATTERING, RADIATION; URINARY BLADDER; WHOLE-BODY COUNTING;

EID: 55149112092     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2008.07.017     Document Type: Article

References (24)

1. Bhatia S., and Sklar C. Second cancers in survivors of childhood cancer. Nat Rev Cancer 2 (2002) 124-132
2. Hall E.J. Intensity-modulated radiation therapy, protons, and the risk of second cancers. Int J Radiat Oncol Biol Phys 65 (2006) 1-7
3. Flint-Richter P., and Sadetzki S. Genetic predisposition for the development of radiation-associated meningioma: an epidemiological study. Lancet Oncol 8 (2007) 403-410
4. Stovall M., Blackwell C.R., Cundiff J., Novack D.H., Palta J.R., Wagner L.K., et al. Fetal dose from radiotherapy with photon beams: report of AAPM Radiation Therapy Committee Task Group No. 36. Med Phys 22 (1995) 63-82
5. d'Errico F., Luszik-Bhadra M., Nath R., Siebert B.R., and Wolf U. Depth dose-equivalent and effective energies of photoneutrons generated by 6-18 MV X-ray beams for radiotherapy. Health Phys 80 (2001) 4-11
6. Lin J.P., Liu W.C., and Lin C.C. Investigation of photoneutron dose equivalent from high-energy photons in radiotherapy. Appl Radiat Isot 65 (2007) 599-604
7. Kry S.F., Salehpour M., Followill D.S., Stovall M., Kuban D.A., White R.A., et al. Out-of field photon and neutron dose equivalents from step-and-shoot intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys 62 (2005) 1204-1216
8. Lomax A.J., Pedroni E., Schaffner B., Scheib S., Schneider U., and Tourovsky A. In: Faulkner K., Carey B., Crellin A., and Harrison R.M. (Eds). Quantitative imaging in oncology: 3D treatment planning for conformal proton therapy by spot scanning (1996), BIR Publication, London 67-71
9. Schneider U., Agosteo S., Pedroni E., and Besserer J. Secondary neutron dose during proton therapy using spot scanning. Int J Radiat Oncol Biol Phys 53 (2002) 244-251
10. Yan X, Titt U, Koehler AM, Newhauser WD. Measurement of neutron dose equivalent to proton therapy patients outside of the proton radiation field NIM A 2002;476:429-34.
11. Wroe A., Rosenfeld A., and Schulte R. Out-of-field dose equivalents delivered by proton therapy of prostate cancer. Med Phys 34 (2007) 3449-3456
12. Mesoloras G., Sandison G.A., Stewart R.D., Farr J.B., and Hsi W.C. Neutron scattered dose equivalent to a fetus from proton radiotherapy of the mother. Med Phys 33 (2006) 2479-2490
13. Zheng Y., Newhauser W., Fontenot J., Koch N., and Mohan R. Monte Carlo simulations of stray neutron radiation exposures in proton therapy. J Nucl Mater 361 (2007) 289-297
14. Schneider U., and Walsh L. Cancer risk estimates from the combined Japanese A-bomb and Hodgkin cohorts for doses relevant to radiotherapy. Radiat Environ Biophys 47 (2008) 253-263
15. Schneider U., and Kaser-Hotz B. A simple dose-response relationship for modelling secondary cancer incidence after radiotherapy. Z Med Phys 15 (2005) 31-37
16. Schneider U., Zwahlen D., Ross D., and Kaser-Hotz B. Estimation of radiation induced cancer from 3D-dose distributions: concept of organ equivalent dose. Int J Radiat Oncol Biol Phys 61 (2005) 1510-1515
17. Kellerer A.M., Nekolla E.A., and Walsh L. On the conversion of solid cancer excess relative risk into lifetime attributable risk. Radiat Environ Biophys 40 (2001) 249-257
18. Schneider U., Lomax A., Pemler P., Besserer J., Ross D., Lombriser N., et al. The impact of IMRT and proton radiotherapy on secondary cancer incidence. Strahlenther Onkol 182 (2006) 647-652
19. Ruben J.D., Davis S., Evans C., Jones P., Gagliardi F., Haynes M., and Hunter A. The effect of intensity-modulated radiotherapy on radiation-induced second malignancies. Int J Radiat Oncol Biol Phys 70 (2008) 1530-1536
20. ICRP 103. Recommendations of the International Commission on Radiological Protection. ICRP Publication 103, 2007, Ann. ICRP 37(2-4).
21. Followill D., Geis P., and Boyer A. Estimates of whole-body dose equivalent produced by beam intensity modulated conformal therapy. Int J Radiat Oncol Biol Phys 38 (1997) 667-672
22. Hall E.J., and Wuu C. Radiation-induced second cancers: the impact of 3D-CRT and IMRT. Int J Radiat Oncol Biol Phys 56 (2003) 83-88
23. Kry S.F., Salehpour M., Followill D., et al. The calculated risk of fatal secondary malignancies from intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys 62 (2005) 1195-1203
24. Travis L.B., Gospodarowicz M., Curtis R.E., Clarke E.A., Andersson M., Glimelius B., et al. Lung cancer following chemotherapy and radiotherapy for Hodgkin's disease. J Natl Cancer Inst 94 (2002) 182-192