Effects of dexmedetomidine on propofol and remifentanil infusion rates during total intravenous anesthesia for spine surgery in adolescents

Paediatric Anaesthesia

Volumn 18, Issue 12, 2008, Pages 1190-1195

  Ngwenyama, Nkanyezi E ^a   Anderson, John ^a   Hoernschemeyer, Daniel G ^a   Tobias, Joseph D ^a,b  

^a University of Missouri   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

Controlled hypotension; Dexmedetomidine; Posterior spinal fusion; Propofol; Remifentanil; Scoliosis

Indexed keywords

DEXMEDETOMIDINE; HYDRALAZINE; PROPOFOL; REMIFENTANIL;

ADOLESCENT; ADULT; ANESTHESIA INDUCTION; ARTICLE; BISPECTRAL INDEX; BLOOD PRESSURE; BODY WEIGHT; CONTROLLED STUDY; DEMOGRAPHY; DRUG ANTAGONISM; HEART RATE; HEMODYNAMICS; HUMAN; IDIOPATHIC SCOLIOSIS; INTRAVENOUS ANESTHESIA; MEAN ARTERIAL PRESSURE; PARAMETRIC TEST; PRIORITY JOURNAL; SPINE FUSION; SPINE SURGERY; SYSTOLIC BLOOD PRESSURE;

ADOLESCENT; ADRENERGIC ALPHA-AGONISTS; ANESTHESIA, INTRAVENOUS; ANESTHETICS, INTRAVENOUS; BLOOD PRESSURE; CHILD; DEXMEDETOMIDINE; ELECTROENCEPHALOGRAPHY; FEMALE; HEART RATE; HUMANS; INTRAOPERATIVE PERIOD; MALE; MONITORING, INTRAOPERATIVE; PIPERIDINES; PROPOFOL; RETROSPECTIVE STUDIES; SCOLIOSIS; SPINAL FUSION; SPINE; YOUNG ADULT;

EID: 55149101973     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/j.1460-9592.2008.02787.x     Document Type: Article

References (33)

1. Sudhir KG, Smith RM, Hall JE et al. Intraoperative awakening for early recognition of possible sequelae during Harrington-rod spinal fusion. Anesth Analg 1976 55 : 526 528.
2. Hall JE, Levine CR, Sudhir KG. Intraoperative awakening to monitor spinal cord function during Harrington instrumentation and spine fusion: description of procedure and report of three cases. J Bone Joint Surg 1978 60 : 533 536.
3. Hoppenfield S, Gross A, Andrews C et al. The ankle clonus test for assessment of the integrity of the spinal cord during operations for scoliosis. J Bone Joint Surg 1997 79 : 208 212.
4. Padberg AM, Bridewell KH. Spinal cord monitoring: current state of the art. Orthop Clin North Am 1999 30 : 407 433.
5. Clapcih AJ, Emerson RG, Roye DP Jr. et al. The effects of propofol, small-dose isoflurane, and nitrous oxide on cortical somatosensory evoked potential and bispectral index monitoring in adolescents undergoing spinal fusion. Anesth Analg 2004 99 : 1334 1340.
6. Imani F, Jafarian A, Hassani V et al. Propofol-alfentanil vs. propofol-remifentanil for posterior spinal fusion including wake-up test. Br J Anaesth 2006 96 : 583 586.
7. Volkes DE, Linskey ME, Armstrong WB. Propofol lipemia mimicking chyle leak during neck dissection. Head Neck 2006 28 : 1147 1149.
8. Beule AG, Wilhelmi F, Kuhnel TS et al. Propofol versus sevoflurane: bleeding in endoscopic surgery. Otolaryngol Head Neck Surg 2007 136 : 45 50.
9. Pascoe PJ, Ilkiw JE, Frischmeyer KJ. The effect of the duration of propofol administration on recovery from anesthesia. Vet Anaesth Analg 2006 33 : 2 7.
10. Cravens GT, Packer DL, Johnson ME. Incidence of propofol infusion syndrome during noninvasive radiofrequency ablation for atrial flutter or fibrillation. Anesthesiology 2007 106 : 1134 1138.
11. Tobias JD. Dexmedetomidine: applications in pediatric critical care and pediatric anesthesiology. Pediatr Crit Care Med 2007 8 : 115 131.
12. Arain SR, Ruehlow RM, Uhrich TD et al. The efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery. Anesth Analg 2004 98 : 153 158.
13. Wysowski DK, Pollock ML. Reports of death with use of propofol (Diprivan) for nonprocedural (long-term) sedation and literature review. Anesthesiology 2006 105 : 1047 1051.
14. Kang TM. Propofol infusion syndrome in critically ill patients. Ann Pharmacother 2002 36 : 1453 1456.
15. Bray RJ. Propofol infusion syndrome in children. Paediatr Anaesth 1998 8 : 491 499.
16. Burow BK, Johnson ME, Packer DL. Metabolic acidosis associated with propofol in the absence of other causative factors. Anesthesiology 2004 101 : 239 241.
17. Vokes DE, Linskey ME, Armstrong WB. Propofol lipemia mimicking chyle leak during neck dissection. Head Neck 2006 28 : 1147 1149.
18. Kill C, Leonhardt A, Wulf H. Lactic acidosis after short-term infusion of propofol for anaesthesia in a child with osteogenesis imperfecta. Paediatr Anaesth 2003 13 : 823 826.
19. Mehta N, DeMunter C, Habibi P et al. Short-term propofol infusions in children. Lancet 1999 354 : 866 867.
20. Reinhart WH, Felix Ch. Influence of propofol on erythrocyte morphology, blood viscosity and platelet function. Clin Hemorheol Microcirc 2003 29 : 33 40.
21. Fourcade O, Simon MF, Litt L et al. Propofol inhibits human platelet aggregation induced by proinflammatory mediators. Anesth Analg 2004 99 : 393 398.
22. Dogan IV, Ovah E, Eti Z et al. The in vitro effects of isoflurane, sevoflurane, and propofol on platelet aggregation. Anesth Analg 1999 88 : 432 436.
23. Hiroshi A, Toshiki M, Shinji N et al. In vivo and in vitro studies of the inhibitory effect of propofol on human platelet aggregation. Anesthesiology 1998 88 : 362 370.
24. Kazama T, Ikeda K, Morita K et al. Awakening propofol concentration with and without blood-effect site equilibration after short-term and long-term administration of propofol and fentanyl anesthesia. Anesthesiology 1998 88 : 928 934.
25. 2-adrenoceptor agonist, reduces anesthetic requirements for patients undergoing minor gynecologic surgery. Anesthesiology 1990 73 : 230 235.
26. Dutta S, Karol MD, Cohen T et al. Effect of dexmedetomidine on propofol requirements in healthy subjects. J Pharm Sci 2001 90 : 172 181.
27. Buhrer M, Mappes A, Lauber R et al. Dexmedetomidine decreases thiopental dose requirement and alters distribution pharmacokinetics. Anesthesiology 1994 80 : 1216 1227.
28. Khan ZP, Munday IT, Jones RM et al. Effects of dexmedetomidine on isoflurane requirements in healthy volunteers: pharmacodynamic and pharmacokinetic interactions. Br J Anaesth 1999 83 : 372 0380.
29. Fragen RJ, Fitzgerald PC. Effect of dexmedetomidine on the minimum alveolar concentration (MAC) of sevoflurane in adults age 55 to 70 years. J Clin Anesth 1999 11 : 466 470.
30. Peden CJ, Cloote AH, Stratford M et al. The effect of dexmedetomidine premedication on the dose requirement of propofol to induce loss of consciousness in patients receiving alfentanil. Anaesthesia 2001 56 : 408 413.
31. Bloom M, Beric A, Bekker A. Dexmedetomidine infusion and somatosensory evoked potentials. J Neurosurg Anesthesiol 2001 13 : 320 322.
32. Thornton C, Lucas MA, Newton DEF et al. Effects of dexmedetomidine on isoflurane requirements in healthy volunteers: auditory and somatosensory evoked responses. Br J Anaesth 1999 83 : 381 386.
33. Mahmoud M, Sadhasivam S, Sestokas AK et al. Loss of transcranial electric motor evoked potentials during pediatric spine surgery with dexmedetomidine. Anesthesiology 2007 106 : 393 396.