Progression to Colorectal Neoplasia in Ulcerative Colitis: Effect of Mesalamine

Clinical Gastroenterology and Hepatology

Volumn 6, Issue 11, 2008, Pages 1225-1230

  Ullman, Thomas ^a   Croog, Victoria ^a   Harpaz, Noam ^a   Hossain, Sabera ^a   Kornbluth, Asher ^a   Bodian, Carol ^a   Itzkowitz, Steven ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESALAZINE;

ADOLESCENT; ADULT; ARTICLE; CANCER GRADING; CANCER GROWTH; CHILD; COHORT ANALYSIS; COLORECTAL TUMOR; CONTROLLED STUDY; DRUG DOSE; DRUG DOSE COMPARISON; DRUG MEGADOSE; DYSPLASIA; FEMALE; FOLLOW UP; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; TUMOR BIOPSY; ULCERATIVE COLITIS;

ADOLESCENT; ADULT; AGED; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHEMOPREVENTION; CHILD; COHORT STUDIES; COLITIS, ULCERATIVE; COLON; COLORECTAL NEOPLASMS; FEMALE; HUMANS; MALE; MESALAMINE; MIDDLE AGED;

EID: 55149098950     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cgh.2008.05.020     Document Type: Article

References (16)

1. Itzkowitz S.H., and Harpaz N. Diagnosis and management of dysplasia in patients with inflammatory bowel diseases. Gastroenterology 126 (2004) 1634-1648
2. van Staa T.P., Card T., Logan R.F., et al. 5-Aminosalicylate use and colorectal cancer risk in inflammatory bowel disease: a large epidemiological study. Gut 54 (2005) 1573-1578
3. Velayos F.S., Terdiman J.P., and Walsh J.M. Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: a systematic review and metaanalysis of observational studies. Am J Gastroenterol 100 (2005) 1345-1353
4. Bernstein C.N., Blanchard J.F., Metge C., et al. Does the use of 5-aminosalicylates in inflammatory bowel disease prevent the development of colorectal cancer?. Am J Gastroenterol 98 (2003) 2784-2788
5. Moody G.A., Jayanthi V., Probert C.S., et al. Long-term therapy with sulphasalazine protects against colorectal cancer in ulcerative colitis: a retrospective study of colorectal cancer risk and compliance with treatment in Leicestershire. Eur J Gastroenterol Hepatol 8 (1996) 1179-1183
6. Pinczowski D., Ekbom A., Baron J., et al. Risk factors for colorectal cancer in patients with ulcerative colitis: a case-control study. Gastroenterology 107 (1994) 117-120
7. Eaden J., Abrams K., Ekbom A., et al. Colorectal cancer prevention in ulcerative colitis: a case-control study. Aliment Pharmacol Ther 14 (2000) 145-153
8. Rubin D.T., LoSavio A., Yadron N., et al. Aminosalicylate therapy in the prevention of dysplasia and colorectal cancer in ulcerative colitis. Clin Gastroenterol Hepatol 4 (2006) 1346-1350
9. Terdiman J.P., Steinbuch M., Blumentals W.A., et al. 5-Aminosalicylic acid therapy and the risk of colorectal cancer among patients with inflammatory bowel disease. Inflamm Bowel Dis 13 (2007) 367-371
10. Ullman T., Croog V., Harpaz N., et al. Progression of flat low-grade dysplasia to advanced neoplasia in patients with ulcerative colitis. Gastroenterology 125 (2003) 1311-1319
11. Riddell R.H., Goldman H., Ransohoff D.F., et al. Dysplasia in inflammatory bowel disease: standardized classification with provisional clinical applications. Hum Pathol 14 (1983) 931-968
12. Cox D.R. Regression models and life tables. J R Stat Soc Ser B Method 34 (1972) 187-220
13. Matula S., Croog V., Itzkowitz S., et al. Chemoprevention of colorectal neoplasia in ulcerative colitis: the effect of 6-mercaptopurine. Clin Gastroenterol Hepatol 3 (2005) 1015-1021
14. Lashner B.A., Heidenreich P.A., Su G.L., et al. Effect of folate supplementation on the incidence of dysplasia and cancer in chronic ulcerative colitis. A case-control study. Gastroenterology 97 (1989) 255-259
15. Lashner B.A., Provencher K.S., Seidner D.L., et al. The effect of folic acid supplementation on the risk for cancer or dysplasia in ulcerative colitis. Gastroenterology 112 (1997) 29-32
16. Velayos F.S., Loftus Jr. E.V., Jess T., et al. Predictive and protective factors associated with colorectal cancer in ulcerative colitis: a case-control study. Gastroenterology 130 (2006) 1941-1949