메뉴 건너뛰기




Volumn 19, Issue 3-4, 2008, Pages 497-514

Implications of new radiobiological insights for the long term management of high level radioactive waste

Author keywords

Epigenetics; Internal emitters; Radiation risk; Radioactive waste; Radiobiology

Indexed keywords

ANIMAL CELL CULTURE; ATOMS; FORECASTING; HEALTH RISKS; INDUSTRIAL WASTE TREATMENT; IONIZING RADIATION; RADIATION; RADIATION EFFECTS; RADIOACTIVE MATERIALS; RADIOACTIVE WASTES; RADIOACTIVITY; RISK ASSESSMENT; RISK MANAGEMENT; RISK PERCEPTION;

EID: 55149084133     PISSN: 0958305X     EISSN: None     Source Type: Journal    
DOI: 10.1260/095830508784641381     Document Type: Article
Times cited : (4)

References (44)
  • 1
    • 0003962786 scopus 로고
    • The Principles of Radioactive Waste Management. Vienna: International Atomic Energy Agency
    • IAEA
    • IAEA (1995) The Principles of Radioactive Waste Management. Vienna: International Atomic Energy Agency. Safety Series No 111FSafety Series No 111F.
    • (1995) Safety Series No 111FSafety Series No 111F
  • 2
    • 55149095331 scopus 로고    scopus 로고
    • Managing Radioactive Waste Safely: CoRWM's recommendations to Government. London: Committee on Radioactive Waste Management
    • CoRWM
    • CoRWM (2006) Managing Radioactive Waste Safely: CoRWM's recommendations to Government. London: Committee on Radioactive Waste Management. CoRWM Doc 700 CoRWM Doc 700.
    • (2006) CoRWM Doc 700 CoRWM Doc , vol.700
  • 3
    • 34249708939 scopus 로고    scopus 로고
    • RBE and w(R) values of Auger emitters and low-range beta emitters with particular reference to tritium
    • Fairlie I (2007) RBE and w(R) values of Auger emitters and low-range beta emitters with particular reference to tritium. J Radiol Prot 27: 157-168.
    • (2007) J Radiol Prot , vol.27 , pp. 157-168
    • Fairlie, I.1
  • 5
    • 0031678469 scopus 로고    scopus 로고
    • An illustrative comparison of the event-size distributions for gamma-rays and alpha-particles in the whole mammalian cell nucleus
    • Baverstock K, Thorne M (1998) An illustrative comparison of the event-size distributions for gamma-rays and alpha-particles in the whole mammalian cell nucleus. Int J Radiat Biol 74: 799-804.
    • (1998) Int J Radiat Biol , vol.74 , pp. 799-804
    • Baverstock, K.1    Thorne, M.2
  • 6
    • 27644579496 scopus 로고    scopus 로고
    • Classical radiation biology, the bystander effect and paradigms: A reply
    • Baverstock K, Belyakov OV (2005) Classical radiation biology, the bystander effect and paradigms: A reply. Hum Exp Toxicol 24: 537-542
    • (2005) Hum Exp Toxicol , vol.24 , pp. 537-542
    • Baverstock, K.1    Belyakov, O.V.2
  • 7
    • 0026515714 scopus 로고
    • Transmission of chromosomal instability after plutonium alpha-particle irradiation
    • Kadhim MA, Macdonald DA, Goodhead DT, Lorimore SA, Marsden SJ, et al. (1992) Transmission of chromosomal instability after plutonium alpha-particle irradiation. Nature 355: 738-740.
    • (1992) Nature , vol.355 , pp. 738-740
    • Kadhim, M.A.1    Macdonald, D.A.2    Goodhead, D.T.3    Lorimore, S.A.4    Marsden, S.J.5
  • 8
    • 0038301529 scopus 로고    scopus 로고
    • Non-targeted and delayed effects of exposure to ionizing radiation: I. Radiation-induced genomic instability and bystander effects in vitro
    • Morgan WF (2003) Non-targeted and delayed effects of exposure to ionizing radiation: I. Radiation-induced genomic instability and bystander effects in vitro. Radiat Res 159: 567-580.
    • (2003) Radiat Res , vol.159 , pp. 567-580
    • Morgan, W.F.1
  • 9
    • 0038640479 scopus 로고    scopus 로고
    • Non-targeted and delayed effects of exposure to ionizing radiation: II. Radiation-induced genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects
    • Morgan WF (2003) Non-targeted and delayed effects of exposure to ionizing radiation: II. Radiation-induced genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects. Radiat Res 159: 581-596.
    • (2003) Radiat Res , vol.159 , pp. 581-596
    • Morgan, W.F.1
  • 10
    • 0026454677 scopus 로고
    • Induction of sister chromatid exchanges by extremely low doses of alpha-particles
    • Nagasawa H, Little JB (1992) Induction of sister chromatid exchanges by extremely low doses of alpha-particles. Cancer Res 52: 6394-6396.
    • (1992) Cancer Res , vol.52 , pp. 6394-6396
    • Nagasawa, H.1    Little, J.B.2
  • 11
    • 0032510735 scopus 로고    scopus 로고
    • Chromosomal instability in the descendants of unirradiated surviving cells after alpha-particle irradiation
    • Lorimore SA, Kadhim MA, Pocock DA, Papworth D, Stevens DL, et al. (1998) Chromosomal instability in the descendants of unirradiated surviving cells after alpha-particle irradiation. Proc Natl Acad Sci U S A 95: 5730-5733.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 5730-5733
    • Lorimore, S.A.1    Kadhim, M.A.2    Pocock, D.A.3    Papworth, D.4    Stevens, D.L.5
  • 12
    • 0037076270 scopus 로고    scopus 로고
    • Elevated mutation rates in the germ line of first- and second-generation offspring of irradiated male mice
    • Barber R, Plumb MA, Boulton E, Roux I, Dubrova YE (2002) Elevated mutation rates in the germ line of first- and second-generation offspring of irradiated male mice. Proc Natl Acad Sci U S A 99: 6877-6882.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 6877-6882
    • Barber, R.1    Plumb, M.A.2    Boulton, E.3    Roux, I.4    Dubrova, Y.E.5
  • 15
    • 33749626120 scopus 로고    scopus 로고
    • Barber RC, Hickenbotham P, Hatch T, Kelly D, Topchiy N, et al. (2006) Radiation-induced transgenerational alterations in genome stability and DNA damage. Oncogene 25: 7336-7342.
    • Barber RC, Hickenbotham P, Hatch T, Kelly D, Topchiy N, et al. (2006) Radiation-induced transgenerational alterations in genome stability and DNA damage. Oncogene 25: 7336-7342.
  • 16
    • 33744917239 scopus 로고    scopus 로고
    • The offspring of irradiated parents, are they stable?
    • Barber RC, Dubrova YE (2006) The offspring of irradiated parents, are they stable? Mutat Res 598: 50-60.
    • (2006) Mutat Res , vol.598 , pp. 50-60
    • Barber, R.C.1    Dubrova, Y.E.2
  • 17
    • 0017098541 scopus 로고
    • Genetic effects of 239Pu salt injections in male mice
    • Luning KG, Frolen H, Nilsson A (1976) Genetic effects of 239Pu salt injections in male mice. Mutat Res 34: 539-542.
    • (1976) Mutat Res , vol.34 , pp. 539-542
    • Luning, K.G.1    Frolen, H.2    Nilsson, A.3
  • 19
    • 0015504248 scopus 로고
    • Rate of depurination of native deoxyribonucleic acid
    • Lindahl T, Nyberg B (1972) Rate of depurination of native deoxyribonucleic acid. Biochemistry 11: 3610-3618.
    • (1972) Biochemistry , vol.11 , pp. 3610-3618
    • Lindahl, T.1    Nyberg, B.2
  • 20
    • 0025778837 scopus 로고
    • DNA instability, paternal irradiation and leukaemia in children around Sellafield
    • Baverstock KF (1991) DNA instability, paternal irradiation and leukaemia in children around Sellafield. Int J Radiat Biol 60: 581-595.
    • (1991) Int J Radiat Biol , vol.60 , pp. 581-595
    • Baverstock, K.F.1
  • 21
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou EP, Boon C, Redon C, Bonner WM (1999) Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 146: 905-916.
    • (1999) J Cell Biol , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 22
    • 0742288019 scopus 로고    scopus 로고
    • Global gene expression responses of fission yeast to ionizing radiation
    • Watson A, Mata J, Bahler J, Carr A, Humphrey T (2004) Global gene expression responses of fission yeast to ionizing radiation. Mol Biol Cell 15: 851-860.
    • (2004) Mol Biol Cell , vol.15 , pp. 851-860
    • Watson, A.1    Mata, J.2    Bahler, J.3    Carr, A.4    Humphrey, T.5
  • 23
    • 0034613840 scopus 로고    scopus 로고
    • Radiation-induced genomic instability: A paradigm -breaking phenomenon and its relevance to environmentally induced cancer
    • Baverstock K (2000) Radiation-induced genomic instability: A paradigm -breaking phenomenon and its relevance to environmentally induced cancer. Mutat Res 454: 89-109.
    • (2000) Mutat Res , vol.454 , pp. 89-109
    • Baverstock, K.1
  • 24
    • 0035807984 scopus 로고    scopus 로고
    • Radiation risk to low fluences of alpha particles may be greater than we thought
    • Zhou H, Suzuki M, Randers-Pehrson G, Vannais D, Chen G, et al. (2001) Radiation risk to low fluences of alpha particles may be greater than we thought. Proc Natl Acad Sci U S A 98: 14410-14415.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 14410-14415
    • Zhou, H.1    Suzuki, M.2    Randers-Pehrson, G.3    Vannais, D.4    Chen, G.5
  • 25
    • 85016340221 scopus 로고    scopus 로고
    • IARC (2000) Ionizing Radiation, Part 1: X- and Gamma (g)-Radiation, and Neutrons. Lyon. 75 75.
    • IARC (2000) Ionizing Radiation, Part 1: X- and Gamma (g)-Radiation, and Neutrons. Lyon. Vol. 75 Vol. 75.
  • 26
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 27
    • 33645236510 scopus 로고    scopus 로고
    • Increased incidence of malignancies in Sweden after the Chernobyl accident - a promoting effect?
    • Tondel M, Lindgren P, Hjalmarsson P, Hardell L, Persson B (2006) Increased incidence of malignancies in Sweden after the Chernobyl accident - a promoting effect? Am J Ind Med 49: 159-168.
    • (2006) Am J Ind Med , vol.49 , pp. 159-168
    • Tondel, M.1    Lindgren, P.2    Hjalmarsson, P.3    Hardell, L.4    Persson, B.5
  • 28
    • 0025773554 scopus 로고
    • Mutator phenotype may be required for multistage carcinogenesis
    • Loeb LA (1991) Mutator phenotype may be required for multistage carcinogenesis. Cancer Res 51: 3075-3079.
    • (1991) Cancer Res , vol.51 , pp. 3075-3079
    • Loeb, L.A.1
  • 30
    • 33751533712 scopus 로고    scopus 로고
    • Endocrine disruptor vinclozolin induced epigenetic transgenerational adult-onset disease
    • Anway MD, Leathers C, Skinner MK (2006) Endocrine disruptor vinclozolin induced epigenetic transgenerational adult-onset disease. Endocrinology 147: 5515-5523.
    • (2006) Endocrinology , vol.147 , pp. 5515-5523
    • Anway, M.D.1    Leathers, C.2    Skinner, M.K.3
  • 31
    • 20344385787 scopus 로고    scopus 로고
    • Epigenetic transgenerational actions of endocrine disruptors and male fertility
    • Anway MD, Cupp AS, Uzumcu M, Skinner MK (2005) Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science 308: 1466-1469.
    • (2005) Science , vol.308 , pp. 1466-1469
    • Anway, M.D.1    Cupp, A.S.2    Uzumcu, M.3    Skinner, M.K.4
  • 32
    • 0028805785 scopus 로고
    • Lack of effects of atomic bomb radiation on genetic instability of tandem-repetitive elements in human germ cells
    • Kodaira M, Satoh C, Hiyama K, Toyama K (1995) Lack of effects of atomic bomb radiation on genetic instability of tandem-repetitive elements in human germ cells. Am J Hum Genet 57: 1275-1283.
    • (1995) Am J Hum Genet , vol.57 , pp. 1275-1283
    • Kodaira, M.1    Satoh, C.2    Hiyama, K.3    Toyama, K.4
  • 33
    • 27444438919 scopus 로고    scopus 로고
    • Clonally expanded T-cell populations in atomic bomb survivors do not show excess levels of chromosome instability
    • Kodama Y, Ohtaki K, Nakano M, Hamasaki K, Awa AA, et al. (2005) Clonally expanded T-cell populations in atomic bomb survivors do not show excess levels of chromosome instability. Radiat Res 164: 618-626.
    • (2005) Radiat Res , vol.164 , pp. 618-626
    • Kodama, Y.1    Ohtaki, K.2    Nakano, M.3    Hamasaki, K.4    Awa, A.A.5
  • 34
    • 0344872802 scopus 로고
    • Cancer incidence in children and young adults did not increase relative to parental exposure to atomic bombs
    • 2003
    • Izumi S, Koyama K, Soda M, Suyama A (2003) Cancer incidence in children and young adults did not increase relative to parental exposure to atomic bombs. Br J Cancer 89: 1709-1713.
    • (1709) Br J Cancer , vol.89
    • Izumi, S.1    Koyama, K.2    Soda, M.3    Suyama, A.4
  • 35
    • 0141634149 scopus 로고    scopus 로고
    • Radiation-related mortality among offspring of atomic bomb survivors: A half-century of follow-up
    • Izumi S, Suyama A, Koyama K (2003) Radiation-related mortality among offspring of atomic bomb survivors: A half-century of follow-up. Int J Cancer 107: 292-297.
    • (2003) Int J Cancer , vol.107 , pp. 292-297
    • Izumi, S.1    Suyama, A.2    Koyama, K.3
  • 36
    • 34347372051 scopus 로고    scopus 로고
    • Molecular basic data calculation for radiation transport in chromatin
    • Peudon A, Edel S, Terrissol M (2006) Molecular basic data calculation for radiation transport in chromatin. Radiat Prot Dosimetry 122: 128-135.
    • (2006) Radiat Prot Dosimetry , vol.122 , pp. 128-135
    • Peudon, A.1    Edel, S.2    Terrissol, M.3
  • 38
    • 28044459809 scopus 로고    scopus 로고
    • DNA breakage by decay of Auger electron emitters: Experiments with 1231-iodoHoechst 33258 and plasmid DNA
    • Lobachevsky PN, Martin RF (2005) DNA breakage by decay of Auger electron emitters: Experiments with 1231-iodoHoechst 33258 and plasmid DNA. Radiat Res 164: 766-773.
    • (2005) Radiat Res , vol.164 , pp. 766-773
    • Lobachevsky, P.N.1    Martin, R.F.2
  • 39
    • 15544363414 scopus 로고    scopus 로고
    • DNA-incorporated 125I induces more than one double-strand break per decay in mammalian cells
    • Elmroth K, Stenerlow B (2005) DNA-incorporated 125I induces more than one double-strand break per decay in mammalian cells. Radiat Res 163: 369-373.
    • (2005) Radiat Res , vol.163 , pp. 369-373
    • Elmroth, K.1    Stenerlow, B.2
  • 40
    • 12344277577 scopus 로고    scopus 로고
    • Computer evaluation of direct and indirect damage induced by free and DNA-bound iodine-125 in the chromatin fibre
    • Terrissol M, Edel S, Pomplun E (2004) Computer evaluation of direct and indirect damage induced by free and DNA-bound iodine-125 in the chromatin fibre. Int J Radiat Biol 80: 905-908.
    • (2004) Int J Radiat Biol , vol.80 , pp. 905-908
    • Terrissol, M.1    Edel, S.2    Pomplun, E.3
  • 41
    • 33846811578 scopus 로고    scopus 로고
    • Using Hoechst 33342 to target radioactivity to the cell nucleus
    • Yasui LS, Chen K, Wang K, Jones TP, Caldwell J, et al. (2007) Using Hoechst 33342 to target radioactivity to the cell nucleus. Radiat Res 167: 167-175.
    • (2007) Radiat Res , vol.167 , pp. 167-175
    • Yasui, L.S.1    Chen, K.2    Wang, K.3    Jones, T.P.4    Caldwell, J.5
  • 42
    • 0033710915 scopus 로고    scopus 로고
    • Production of clustered DNA damage by 125I decay
    • Yasui LS, Hughes A, DeSombre ER (2000) Production of clustered DNA damage by 125I decay. Acta Oncol 39: 739-740.
    • (2000) Acta Oncol , vol.39 , pp. 739-740
    • Yasui, L.S.1    Hughes, A.2    DeSombre, E.R.3
  • 43
    • 0036027851 scopus 로고    scopus 로고
    • Bystander effects caused by nonuniform distributions of DNA-incorporated (125)I
    • Howell RW, Bishayee A (2002) Bystander effects caused by nonuniform distributions of DNA-incorporated (125)I. Micron 33: 127-132.
    • (2002) Micron , vol.33 , pp. 127-132
    • Howell, R.W.1    Bishayee, A.2
  • 44
    • 35348896661 scopus 로고    scopus 로고
    • Biological response to nonuniform distributions of (210)Po in multicellular clusters
    • Neti PV, Howell RW (2007) Biological response to nonuniform distributions of (210)Po in multicellular clusters. Radiat Res 168: 332-340.
    • (2007) Radiat Res , vol.168 , pp. 332-340
    • Neti, P.V.1    Howell, R.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.