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Volumn 55, Issue 5, 2008, Pages 827-837

Effects of leptin on lipid metabolism and gene expression of differentiation-associated growth factors and transcription factors during differentiation and maturation of 3T3-L1 preadipocytes

Author keywords

Adipocyte; Differentiation; IGF I; Leptin; Lipid; PPAR

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; GLYCEROL; INSULIN; LEPTIN; LIPID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA;

EID: 55049142093     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.K08E-115     Document Type: Article
Times cited : (27)

References (42)
  • 3
    • 0033964872 scopus 로고    scopus 로고
    • Lipodystrophies
    • Garg A (2000) Lipodystrophies. Am J Med 108: 143-152.
    • (2000) Am J Med , vol.108 , pp. 143-152
    • Garg, A.1
  • 4
    • 0034611791 scopus 로고    scopus 로고
    • Obesity as a medical problem
    • Kopelman PG (2000) Obesity as a medical problem. Nature 404: 635-643.
    • (2000) Nature , vol.404 , pp. 635-643
    • Kopelman, P.G.1
  • 5
    • 0023919926 scopus 로고
    • Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes
    • Smith PJ, Wise LS, Berkowitz, R, Wan C, Rubin CS (1988) Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes. J Biol Chem 263: 402-408.
    • (1988) J Biol Chem , vol.263 , pp. 402-408
    • Smith, P.J.1    Wise, L.S.2    Berkowitz, R.3    Wan, C.4    Rubin, C.S.5
  • 6
    • 0029391352 scopus 로고
    • The role of growth hormone/insulin-like growth factors in adipocyte differentiation
    • Wabitsch M, Hauner H, Heinze E, Teller WM (1995) The role of growth hormone/insulin-like growth factors in adipocyte differentiation. Metabolism 44: 45-49.
    • (1995) Metabolism , vol.44 , pp. 45-49
    • Wabitsch, M.1    Hauner, H.2    Heinze, E.3    Teller, W.M.4
  • 9
    • 0342542810 scopus 로고
    • Type β transforming growth factor controls the adipogenic differentiation of 3T3 fibroblasts
    • Ignotz PA, Massague J (1985) Type β transforming growth factor controls the adipogenic differentiation of 3T3 fibroblasts. Proc Natl Acad Sci USA 82: 8530-8534.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 8530-8534
    • Ignotz, P.A.1    Massague, J.2
  • 10
    • 0038322020 scopus 로고    scopus 로고
    • Transforming growth factor-β inhibits adipocyte differentiation by Smad3 interacting with CCAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function
    • Choy L, Derynck R (2003) Transforming growth factor-β inhibits adipocyte differentiation by Smad3 interacting with CCAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function. J Biol Chem 278: 9609-9619.
    • (2003) J Biol Chem , vol.278 , pp. 9609-9619
    • Choy, L.1    Derynck, R.2
  • 11
    • 0031821520 scopus 로고    scopus 로고
    • Understanding adipocyte differentiation
    • Gregoire FM, Smas CM, Sul HS (1998) Understanding adipocyte differentiation. Physiol Rev 78: 783-809.
    • (1998) Physiol Rev , vol.78 , pp. 783-809
    • Gregoire, F.M.1    Smas, C.M.2    Sul, H.S.3
  • 13
    • 0034970334 scopus 로고    scopus 로고
    • The roles of PPARs in adipocyte differentiation
    • Grimaldi PA (2001) The roles of PPARs in adipocyte differentiation. Prog Lipid Res 40: 269-281.
    • (2001) Prog Lipid Res , vol.40 , pp. 269-281
    • Grimaldi, P.A.1
  • 14
    • 0028909362 scopus 로고
    • Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes
    • Amri EZ, Bonino F, Ailhaud G, Abumrad NA, Grimaldi PA (1995) Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. J Biol Chem 270: 2367-2371.
    • (1995) J Biol Chem , vol.270 , pp. 2367-2371
    • Amri, E.Z.1    Bonino, F.2    Ailhaud, G.3    Abumrad, N.A.4    Grimaldi, P.A.5
  • 15
    • 0034623142 scopus 로고    scopus 로고
    • Modulation of the murine peroxisome proliferator-activated receptor gamma 2 promoter activity by CCAAT/enhancer-binding proteins
    • Elberg G, Gimble JM, Tsai SY (2000) Modulation of the murine peroxisome proliferator-activated receptor gamma 2 promoter activity by CCAAT/enhancer-binding proteins. J Biol Chem 275: 27815-27822.
    • (2000) J Biol Chem , vol.275 , pp. 27815-27822
    • Elberg, G.1    Gimble, J.M.2    Tsai, S.Y.3
  • 16
    • 0028129499 scopus 로고
    • Ectopic expression of the CCAAT/enhancer binding protein alpha promotes the adipogenic program in a variety of mouse fibroblastic cells
    • Freytag SO, Paielli DL, Gilbert JD (1994) Ectopic expression of the CCAAT/enhancer binding protein alpha promotes the adipogenic program in a variety of mouse fibroblastic cells. Genes Dev 8: 1654-1663.
    • (1994) Genes Dev , vol.8 , pp. 1654-1663
    • Freytag, S.O.1    Paielli, D.L.2    Gilbert, J.D.3
  • 17
    • 0029791412 scopus 로고    scopus 로고
    • PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
    • Schoonjans K, Peinado-Onsurbe J, Lefebvre AM, Heyman RA, Briggs M, Deeb S, Staels B, Auwerx J (1996) PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J 15: 5336-5348.
    • (1996) EMBO J , vol.15 , pp. 5336-5348
    • Schoonjans, K.1    Peinado-Onsurbe, J.2    Lefebvre, A.M.3    Heyman, R.A.4    Briggs, M.5    Deeb, S.6    Staels, B.7    Auwerx, J.8
  • 19
  • 21
    • 0029078449 scopus 로고
    • Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes
    • MacDougald OA, Hwang CS, Fan H, Lane MD (1995) Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes. Proc Natl Acad Sci USA 92: 9034-9037.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9034-9037
    • MacDougald, O.A.1    Hwang, C.S.2    Fan, H.3    Lane, M.D.4
  • 23
    • 0018869666 scopus 로고
    • Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes
    • Student, A.K., Hsu, R.Y., Lane, M.D., 1980. Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes. J Biol Chem 255: 4745-4750.
    • (1980) J Biol Chem , vol.255 , pp. 4745-4750
    • Student, A.K.1    Hsu, R.Y.2    Lane, M.D.3
  • 25
    • 0037147144 scopus 로고    scopus 로고
    • Calcineurin mediates the calcium-dependent inhibition of adipocyte differentiaion in 3T3-L1 cells
    • Neal JW, Clipstone NA (2002) Calcineurin mediates the calcium-dependent inhibition of adipocyte differentiaion in 3T3-L1 cells. J Biol Chem 277: 49776-49781.
    • (2002) J Biol Chem , vol.277 , pp. 49776-49781
    • Neal, J.W.1    Clipstone, N.A.2
  • 26
    • 0016693548 scopus 로고
    • An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion
    • Green H, Kehinde O (1975) An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion. Cell 1: 19-27.
    • (1975) Cell , vol.1 , pp. 19-27
    • Green, H.1    Kehinde, O.2
  • 27
    • 0026793195 scopus 로고
    • Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O
    • Ramirez-Zacarias JL, Castro-Munozledo F, Kuri-Harcuch W (1992) Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O. Histochemistry 97: 493-497.
    • (1992) Histochemistry , vol.97 , pp. 493-497
    • Ramirez-Zacarias, J.L.1    Castro-Munozledo, F.2    Kuri-Harcuch, W.3
  • 29
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 30
    • 12344331802 scopus 로고    scopus 로고
    • Expression of relationship of the insulin like growth factor system with posthatch growth in Korean Native Ogol Chicken
    • Yun JS, Seo DS, Kim WK, Ko Y (2005) Expression of relationship of the insulin like growth factor system with posthatch growth in Korean Native Ogol Chicken. Poultry Sci 84: 83-90.
    • (2005) Poultry Sci , vol.84 , pp. 83-90
    • Yun, J.S.1    Seo, D.S.2    Kim, W.K.3    Ko, Y.4
  • 31
    • 0034537601 scopus 로고    scopus 로고
    • Secretory, endocrine and autocrine/paracrine function of the adipocyte
    • Kim S, Moustaid-Moussa N (2000) Secretory, endocrine and autocrine/paracrine function of the adipocyte. J Nutr 130: 3110S-3115S.
    • (2000) J Nutr , vol.130
    • Kim, S.1    Moustaid-Moussa, N.2
  • 32
    • 2342586061 scopus 로고    scopus 로고
    • The adipocyte as an endocrine cell
    • Miner JL (2004) The adipocyte as an endocrine cell. J Anim Sci 82: 935-941.
    • (2004) J Anim Sci , vol.82 , pp. 935-941
    • Miner, J.L.1
  • 36
    • 33645998442 scopus 로고    scopus 로고
    • Porcine preadipocyte proliferation and differentiation: A role for leptin?
    • Ramsay TG (2005) Porcine preadipocyte proliferation and differentiation: a role for leptin? J Anim Sci 83: 2066-2074.
    • (2005) J Anim Sci , vol.83 , pp. 2066-2074
    • Ramsay, T.G.1
  • 37
    • 33744804529 scopus 로고    scopus 로고
    • Direct and indirect effects of leptin on preadipocyte proliferation and differentiation
    • Wagoner B, Hausman, DB, Harris RBS (2006) Direct and indirect effects of leptin on preadipocyte proliferation and differentiation. Am J Physiol Regul Integr Comp Physiol 290: R1557-R1564.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290
    • Wagoner, B.1    Hausman, D.B.2    Harris, R.B.S.3
  • 38
    • 15844410399 scopus 로고    scopus 로고
    • Obese gene expression alters the ability of 30A5 preadipocytes to respond to lipogenic hormones
    • Bai Y, Zhang S, Kim KS, Lee JK, Kim KH (1996) Obese gene expression alters the ability of 30A5 preadipocytes to respond to lipogenic hormones. J Biol Chem 271: 13939-13942.
    • (1996) J Biol Chem , vol.271 , pp. 13939-13942
    • Bai, Y.1    Zhang, S.2    Kim, K.S.3    Lee, J.K.4    Kim, K.H.5
  • 39
    • 0031587418 scopus 로고    scopus 로고
    • In vitro lipolytic effect of leptin on mouse adipocytes: Evidence for a possible autocrine/paracrine role of leptin
    • Fruhbeck G, Aguado M, Martinez JA (1997) In vitro lipolytic effect of leptin on mouse adipocytes: evidence for a possible autocrine/paracrine role of leptin. Biochem Biophys Res Commun 240: 590-594.
    • (1997) Biochem Biophys Res Commun , vol.240 , pp. 590-594
    • Fruhbeck, G.1    Aguado, M.2    Martinez, J.A.3
  • 40
    • 0036923174 scopus 로고    scopus 로고
    • Leptin controls the fate of fatty acids in isolated rat white adipocytes
    • William Jr WN, Ceddia RB, Curi R (2002) Leptin controls the fate of fatty acids in isolated rat white adipocytes. J Endocrinol 175: 735-744.
    • (2002) J Endocrinol , vol.175 , pp. 735-744
    • William Jr, W.N.1    Ceddia, R.B.2    Curi, R.3
  • 41
    • 0036039783 scopus 로고    scopus 로고
    • In vitro effects of leptin on human adipocyte metabolism
    • Elimam A, Kamel A, Marcus C (2002) In vitro effects of leptin on human adipocyte metabolism. Horm Res 58: 88-93.
    • (2002) Horm Res , vol.58 , pp. 88-93
    • Elimam, A.1    Kamel, A.2    Marcus, C.3
  • 42
    • 0036819249 scopus 로고    scopus 로고
    • Changes in IGF-I receptor and IGF-I mRNA during differentiation of 3T3-L1 preadipocytes
    • Zizola CF, Balana ME, Sandoval M, Calvo JC (2002) Changes in IGF-I receptor and IGF-I mRNA during differentiation of 3T3-L1 preadipocytes. Biochimie 84: 975-980.
    • (2002) Biochimie , vol.84 , pp. 975-980
    • Zizola, C.F.1    Balana, M.E.2    Sandoval, M.3    Calvo, J.C.4


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