Thrombotic thrombocytopenic purpura in a patient with very early pregnancy: Clinical presentation and autopsy findings

Blood Coagulation and Fibrinolysis

Volumn 19, Issue 7, 2008, Pages 727-730

  Sharma, Aman ^a   Radotra, Bishan ^a   Wanchu, Ajay ^a   Malhotra, Pankaj ^a   Singh, Surjit ^a   Varma, Subhash ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Histopathological findings; Pregnancy; Thrombotic thrombocytopenic purpura

Indexed keywords

D DIMER; FIBRINOGEN; HEMOGLOBIN;

ADULT; AGGLUTINATION TEST; ANEMIA; ARTICLE; AUTOPSY; BLOOD VESSEL OCCLUSION; BRAIN TUMOR; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; ELECTRON MICROSCOPY; ERYTHROCYTE TRANSFUSION; FEMALE; FIRST TRIMESTER PREGNANCY; GESTATION PERIOD; GRANULOMA; HEMOGLOBIN BLOOD LEVEL; HUMAN; HUMAN TISSUE; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTHROMBIN TIME; SEIZURE; SENSORY DYSFUNCTION; THROMBOTIC THROMBOCYTOPENIC PURPURA; VAGINA BLEEDING;

ADULT; AUTOPSY; FATAL OUTCOME; FEMALE; HUMANS; MICROSCOPY, ELECTRON; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; PURPURA, THROMBOTIC THROMBOCYTOPENIC;

EID: 55049139370     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/MBC.0b013e32830ef8de     Document Type: Article

References (16)

1. Nabhan C, Kwaan HC. Current concepts in the diagnosis and management of thrombotic thrombocytopenic purpura. Hematol Oncol Clin North Am 2003; 17:177-199.
2. Moake JL. Thrombotic microangiopathies. N Engl J Med 2002; 347:589-600.
3. McMinn JR, George JN. Evaluation of women with clinically suspected thrombotic thrombocytopenic purpura-hemolytic uremic syndrome during pregnancy. J Clin Apher 2001; 16:202-209.
4. Weiner CP. Thrombotic microangiopathy in pregnancy and the postpartum period. Semin Hematol 1987; 24:119-129.
5. Mokrzycki MH, Rickles FR, Kaplan AA, Kohn OF. Thrombotic thrombocytopenic purpura in pregnancy: successful treatment with plasma exchange. Case report and review of the literature. Blood Purif 1995; 13:271-282.
6. Torok TJ, Hofman RC, Chorba TL. Increasing mortality from thrombotic thrombocytopenic purpura in the United States: analysis of national mortality data. Am J Hematol 1995; 50:84-90.
7. Rock GA, Shumak KH, Buskard NA, Blanchette VS, Kelton JG, Nair RC, Spasoff RA. Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. N Engl J Med 1991; 325:393-397.
8. Allford SL, Hunt BJ, Rose P, Machin SJ, on behalf of the Haemostasis and Thrombosis Task Force of the British Committee for Standards in Haematology. Guidelines on the diagnosis and management of the thrombotic microangiopathic hemolytic anemias. Br J Hematol 2003; 120:556-573.
9. Rose M, Eldor A. High incidence of relapses in thrombotic thrombocytopenic purpura. Clinical study of 38 patients. Am J Med 1987;83:437-444.
10. Tache V, Towner D, Xing G, Gilbert W. Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) in pregnancy: a population based study. Am J Obstet Gynecol 2006; 195:S202.
11. Wada H, Mori Y, Shimura M, Hiyoyama K, Ioka M, Nakasaki T, et al. Poor outcome in disseminated intravascular coagulation or thrombotic thrombocytopenic purpura patients with severe vascular endothelial cell injuries. Am J Hematol 1998; 58:189-194.
12. Musio F, Bohen EM, Yuan CM, Welch PG. Review of thrombotic thrombocytopenic purpura in the setting of systemic lupus erythematosus.. Semin Arthritis Rheum 1998; 28:1-19.
13. Kojouri K, Vesely SK, George JN. Quinine-associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: frequency, clinical features, and long-term outcomes. Ann Intern Med 2001; 135:1047-1051.
14. Baron JM, Baron BW. Thrombotic thrombocytopenic purpura and its look alikes. Clin Adv Hematol Oncol 2005; 3:868-874.
15. Matsuda J, Sanaka T, Gonichi K, Matsui K, Uchida S, Matsumoto M, Fujimura Y. Occurrence of thrombotic thrombocytopenic purpura in a systemic lupus erythematosus patient with antiphospholipid antibodies in association with a decreased activity of von Willebrand factor-cleaving protease. Lupus 2002; 11:463-464.
16. Sarode R, Gottschall JL, Aster RH, McFarland JG. Thrombotic thrombocytopenic purpura: early and late responders. Am J Hematol 1997; 54:102-107.