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1
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0031882729
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Andersson 1998 {published data only} Andersson OK, Neldam S. The antihypertensive effect and tolerability of candesartan cilexitil, a new generation angiotensin II antagonist, in comparison with losartan. Blood Pressure 1998;7(1):53-9.
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Andersson 1998 {published data only} Andersson OK, Neldam S. The antihypertensive effect and tolerability of candesartan cilexitil, a new generation angiotensin II antagonist, in comparison with losartan. Blood Pressure 1998;7(1):53-9.
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2
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0034061492
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Benetos 2000 {published data only} Benetos A, Gautier S, Lafleche A, Topouchian J, Frangin G, Girerd X, Sissmann J, Safar ME. Blockade of angiotensin II type 1 receptors: Effect on carotid and radial artery structure and function in hypertensive humans. Journal of Vascular Research 2000;37(1):8-15.
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Benetos 2000 {published data only} Benetos A, Gautier S, Lafleche A, Topouchian J, Frangin G, Girerd X, Sissmann J, Safar ME. Blockade of angiotensin II type 1 receptors: Effect on carotid and radial artery structure and function in hypertensive humans. Journal of Vascular Research 2000;37(1):8-15.
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3
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0032436072
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Benz 1998 {published data only} Benz JR, Black HR, Graff A, Reed A, Fitzsimmons S, Shi Y. Valsartan and hydrochlorothiazide in patients with essential hypertension. A multiple dose, double-blind, placebo controlled trial comparing combination therapy with monotherapy. Journal of Human Hypertension 1998;12(12):861-6.
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Benz 1998 {published data only} Benz JR, Black HR, Graff A, Reed A, Fitzsimmons S, Shi Y. Valsartan and hydrochlorothiazide in patients with essential hypertension. A multiple dose, double-blind, placebo controlled trial comparing combination therapy with monotherapy. Journal of Human Hypertension 1998;12(12):861-6.
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4
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0030846109
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Black 1997 {published data only} Black HR, Graff A, Shute D, Stoltz R, Ruff D, Levine J, Shi Y, Mallows S. Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy, tolerability and safety compared to an angiotensin-converting enzyme inhibitor, lisinopril. Journal of Human Hypertension 1997;11(8):483-9.
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Black 1997 {published data only} Black HR, Graff A, Shute D, Stoltz R, Ruff D, Levine J, Shi Y, Mallows S. Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy, tolerability and safety compared to an angiotensin-converting enzyme inhibitor, lisinopril. Journal of Human Hypertension 1997;11(8):483-9.
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5
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0038042008
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Chrysant 2003 {published data only} Chrysant SG, Marbury TC, Robinson TD. Antihypertensive efficacy and safety of olmesartan medoxomil compared with amlodipine for mild-to-moderate hypertension. Journal of Human Hypertension 2003;17(6):425-32.
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Chrysant 2003 {published data only} Chrysant SG, Marbury TC, Robinson TD. Antihypertensive efficacy and safety of olmesartan medoxomil compared with amlodipine for mild-to-moderate hypertension. Journal of Human Hypertension 2003;17(6):425-32.
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6
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1442299290
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Chrysant 2004 {published data only} Chrysant SG, Weber MA, Wang AC, Hinman DJ. Evaluation of antihypertensive therapy with the combination of olmesartan medoxomil and hydrochlorothiazide. American Journal of Hypertension 2004;17(3):252-9.
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Chrysant 2004 {published data only} Chrysant SG, Weber MA, Wang AC, Hinman DJ. Evaluation of antihypertensive therapy with the combination of olmesartan medoxomil and hydrochlorothiazide. American Journal of Hypertension 2004;17(3):252-9.
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7
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0036225666
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Cushman 2002 {published data only} Cushman WC, Brady WE, Gazdick LP, Zeldin RK. The effect of a losartan-based treatment regimen on isolated systolic hypertension. Journal of Clinical Hypertension 2002;4(2):101-7.
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Cushman 2002 {published data only} Cushman WC, Brady WE, Gazdick LP, Zeldin RK. The effect of a losartan-based treatment regimen on isolated systolic hypertension. Journal of Clinical Hypertension 2002;4(2):101-7.
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8
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0035146855
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Farsang 2001 {published data only} Farsang C, Kawecka-Jaszcz K, Langan J, Maritz F, Zannad F. Antihypertensive effects and tolerability of candesartan cilexitil alone and in combination with amlodipine. Clinical Drug Investigation 2001;21(1):17-23.
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Farsang 2001 {published data only} Farsang C, Kawecka-Jaszcz K, Langan J, Maritz F, Zannad F. Antihypertensive effects and tolerability of candesartan cilexitil alone and in combination with amlodipine. Clinical Drug Investigation 2001;21(1):17-23.
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9
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0030686557
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Feldman 1997 {published data only} Feldman R, Chattman MS, Lonigro A, Sievers RJ. Tasosartan in patients with essential hypertension: A randomized, double-blind, dose-titration study. Advances in Therapy 1997;14(5):290-303.
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Feldman 1997 {published data only} Feldman R, Chattman MS, Lonigro A, Sievers RJ. Tasosartan in patients with essential hypertension: A randomized, double-blind, dose-titration study. Advances in Therapy 1997;14(5):290-303.
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10
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17944378050
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-
Flack 2001 {published data only} Flack JM, Saunders E, Gradman A, Kraus WE, Lester M, Pratt H, Alderman M, Green S, Vargas R, Espenshade M, Ceesay P, Alexander J, Goldberg A. Antihypertensive efficacy and safety of losartan alone and in combination with hydrochlorothiazide in adult african americans with mild to moderate hypertension. Clinical Therapeutics 2001;23(8):1193-208.
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Flack 2001 {published data only} Flack JM, Saunders E, Gradman A, Kraus WE, Lester M, Pratt H, Alderman M, Green S, Vargas R, Espenshade M, Ceesay P, Alexander J, Goldberg A. Antihypertensive efficacy and safety of losartan alone and in combination with hydrochlorothiazide in adult african americans with mild to moderate hypertension. Clinical Therapeutics 2001;23(8):1193-208.
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11
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0037414091
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Flack 2003 {published data only} Flack JM, Oparil S, Pratt JH, Roniker B, Garthwaite S, Kleiman JH, Yang Y, Krause SL, Workman D, Saunders E. Efficacy and tolerability of eplerenone and losartan in hypertensive black and white patients. Journal of the American College of Cardiology 2003;41(7):1148-55.
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Flack 2003 {published data only} Flack JM, Oparil S, Pratt JH, Roniker B, Garthwaite S, Kleiman JH, Yang Y, Krause SL, Workman D, Saunders E. Efficacy and tolerability of eplerenone and losartan in hypertensive black and white patients. Journal of the American College of Cardiology 2003;41(7):1148-55.
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12
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6844258187
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Fogari 1997 {published data only} Fogari R, Ambrosoli S, Corradi L, Esposti ED, Mos L, Nami R, Nicrosini F, Pessina AC, Salvetti A, Vaccarella A, Zanchetti A, Martin A, Reeves RA. 24-hour blood pressure control by once-daily administration of irbesartan assessed by ambulatory blood pressure monitoring. Journal of Hypertension 1997;15(12 Pt 1):1511-8.
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Fogari 1997 {published data only} Fogari R, Ambrosoli S, Corradi L, Esposti ED, Mos L, Nami R, Nicrosini F, Pessina AC, Salvetti A, Vaccarella A, Zanchetti A, Martin A, Reeves RA. 24-hour blood pressure control by once-daily administration of irbesartan assessed by ambulatory blood pressure monitoring. Journal of Hypertension 1997;15(12 Pt 1):1511-8.
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13
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0035016173
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Fogari 2001 {published data only} Fogari R, Zoppi A, Malamani G, Marasi G, Pesce RM, Banderali A, Mugellini A. Effects of four angiotensin II-receptor antagonists on fibrolysis in postemenopausal women with hypertension. Current Therapeutic Research 2001;62(1):68-78.
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Fogari 2001 {published data only} Fogari R, Zoppi A, Malamani G, Marasi G, Pesce RM, Banderali A, Mugellini A. Effects of four angiotensin II-receptor antagonists on fibrolysis in postemenopausal women with hypertension. Current Therapeutic Research 2001;62(1):68-78.
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14
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0029065095
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Gradman 1995 {published data only} Gradman AH, Arcuri KE, Goldberg AI, Ikeda LS, Nelson EB, Snavely DB, Sweet CS. A randomized, placebo-controlled, double-blind, parallel study of various doses of losartan potassium compared with enalapril maleate in patients with essential hypertension. Hypertension 1995;25(6):1345-50.
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Gradman 1995 {published data only} Gradman AH, Arcuri KE, Goldberg AI, Ikeda LS, Nelson EB, Snavely DB, Sweet CS. A randomized, placebo-controlled, double-blind, parallel study of various doses of losartan potassium compared with enalapril maleate in patients with essential hypertension. Hypertension 1995;25(6):1345-50.
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15
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0032946886
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Gradman 1999 {published data only} Gradman AH, Gray J, Maggiacomo F, Punzi H, White WB. Assessment of once-daily eprosartan, an angiotensin II antagonist, in patients with systemic hypertension. Clinical Therapeutics 1999;21(3):442-53.
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Gradman 1999 {published data only} Gradman AH, Gray J, Maggiacomo F, Punzi H, White WB. Assessment of once-daily eprosartan, an angiotensin II antagonist, in patients with systemic hypertension. Clinical Therapeutics 1999;21(3):442-53.
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16
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14844363404
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Gradman 2005 {published data only} Gradman AH, Schmieder RE, Lins RL, Nussberger J, Chiang Y, Bedigian MP. Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation 2005;111(8):1012-8.
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Gradman 2005 {published data only} Gradman AH, Schmieder RE, Lins RL, Nussberger J, Chiang Y, Bedigian MP. Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation 2005;111(8):1012-8.
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17
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0031958130
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Guthrie 1998 {published data only} Guthrie R, Saini R, Herman T, Pleskow W, Sprecher D, Collins G. Efficacy and tolerability of irbesartan, an angiotensin II receptor antagonist, in primary hypertension. Clinical Drug Investigation 1998;15(3):217-27.
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Guthrie 1998 {published data only} Guthrie R, Saini R, Herman T, Pleskow W, Sprecher D, Collins G. Efficacy and tolerability of irbesartan, an angiotensin II receptor antagonist, in primary hypertension. Clinical Drug Investigation 1998;15(3):217-27.
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Hanefeld 2001 {published data only} Hanefeld M, Abletshauser C. Effect of the angiotensin II receptor antagonist valsartan on lipid profile and glucose metabolism in patients with hypertension. Journal of International Medical Research 2001;29(4):270-9.
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Hanefeld 2001 {published data only} Hanefeld M, Abletshauser C. Effect of the angiotensin II receptor antagonist valsartan on lipid profile and glucose metabolism in patients with hypertension. Journal of International Medical Research 2001;29(4):270-9.
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19
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Hedner 1999 {published data only} Hedner T, Oparil S, Rasmussen K, Rapelli A, Gatlin M, Kobi P, Sullivan J, Oddou-Stock P. A comparison of the angiotensin II antagonists valsartan and losartan in the treatment of essential hypertension. American Journal of Hypertension 1999;12(4 Pt 1):414-7.
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Hedner 1999 {published data only} Hedner T, Oparil S, Rasmussen K, Rapelli A, Gatlin M, Kobi P, Sullivan J, Oddou-Stock P. A comparison of the angiotensin II antagonists valsartan and losartan in the treatment of essential hypertension. American Journal of Hypertension 1999;12(4 Pt 1):414-7.
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20
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Holwerda 1996 {published data only} Holwerda NJ, Fogari R, Angeli P, Porcellati C, Hereng C, Oddou-Stock P, Heath R, Bodin F. Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared with placebo and enalapril. Journal of Hypertension 1996;14(9):1147-51.
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Holwerda 1996 {published data only} Holwerda NJ, Fogari R, Angeli P, Porcellati C, Hereng C, Oddou-Stock P, Heath R, Bodin F. Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared with placebo and enalapril. Journal of Hypertension 1996;14(9):1147-51.
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21
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Ikeda 1997 {published data only} Ikeda LS, Harm SC, Arcuri KE, Goldberg AI, Sweet CS. Comparative antihypertensive effects of losartan 50 mg and losartan 50 mg titrated to 100 mg in patients with essential hypertension. Blood Pressure 1997;6(1):35-43.
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Ikeda 1997 {published data only} Ikeda LS, Harm SC, Arcuri KE, Goldberg AI, Sweet CS. Comparative antihypertensive effects of losartan 50 mg and losartan 50 mg titrated to 100 mg in patients with essential hypertension. Blood Pressure 1997;6(1):35-43.
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Kassler-Taub 1998 {published data only} Kassler-Taub K, Littlejohn T, Elliott W, Ruddy T, Adler E. Comparative efficacy of two angiotensin II receptor antagonists, irbesartan and losartan, in mild-to-moderate hypertension. American Journal of Hypertension 1998;11(4 Pt 1):445-53.
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Kassler-Taub 1998 {published data only} Kassler-Taub K, Littlejohn T, Elliott W, Ruddy T, Adler E. Comparative efficacy of two angiotensin II receptor antagonists, irbesartan and losartan, in mild-to-moderate hypertension. American Journal of Hypertension 1998;11(4 Pt 1):445-53.
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23
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Klingbeil 2002 {published data only} Klingbeil AU, John S, Schneider MP, Jacobi J, Handrock R, Schmieder RE. Effect of AT1 receptor blockade on endothelial function in essential hypertension. American Journal of Hypertension 2003;16(2):123-8.
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Klingbeil 2002 {published data only} Klingbeil AU, John S, Schneider MP, Jacobi J, Handrock R, Schmieder RE. Effect of AT1 receptor blockade on endothelial function in essential hypertension. American Journal of Hypertension 2003;16(2):123-8.
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24
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* Klingbeil AU, John S, Schneider MP, Jacobi J, Weidinger G, Schmieder RE. AT1-receptor blockade improves augmentation index: a double-blind, randomized, controlled study. Journal of Hypertension 2002;20(12):2423-8.
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* Klingbeil AU, John S, Schneider MP, Jacobi J, Weidinger G, Schmieder RE. AT1-receptor blockade improves augmentation index: a double-blind, randomized, controlled study. Journal of Hypertension 2002;20(12):2423-8.
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25
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Kochar 1999 {published data only} Kochar M, Guthrie R, Triscari J, Kassler-Taub K, Reeves RA. Matrix study of irbesartan with hydrochlorothiazide in mild-to-moderate hypertension. American Journal of Hypertension 1999;12(8Pt 1):797-805.
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Kochar 1999 {published data only} Kochar M, Guthrie R, Triscari J, Kassler-Taub K, Reeves RA. Matrix study of irbesartan with hydrochlorothiazide in mild-to-moderate hypertension. American Journal of Hypertension 1999;12(8Pt 1):797-805.
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26
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Lacourciere 1998 {published data only} Lacourciere Y, Pool JL, Svetkey L, Gradman AH, Larochelle P, de Champlain J, Smith WB. A randomized, double-blind, placebo-controlled, parallel-group, multicenter trial of four doses of tasosartan in patients with essential hypertension. American Journal of Hypertension 1998;11(4 Pt 1):454-61.
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Lacourciere 1998 {published data only} Lacourciere Y, Pool JL, Svetkey L, Gradman AH, Larochelle P, de Champlain J, Smith WB. A randomized, double-blind, placebo-controlled, parallel-group, multicenter trial of four doses of tasosartan in patients with essential hypertension. American Journal of Hypertension 1998;11(4 Pt 1):454-61.
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Mallion 1999 {published data only} Mallion JM, Siche JP, Lacourciere Y. ABPM comparison of the antihypertensive profiles of the selective angiotensin II receptor antagonists telmisartan and losartan in patients with mild-to-moderate hypertension. Journal of Human Hypertension 1999;13(10):657-64.
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Mallion 1999 {published data only} Mallion JM, Siche JP, Lacourciere Y. ABPM comparison of the antihypertensive profiles of the selective angiotensin II receptor antagonists telmisartan and losartan in patients with mild-to-moderate hypertension. Journal of Human Hypertension 1999;13(10):657-64.
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Manolis 2004 {published data only} Manolis AJ, Reid JL, de Zeeuw D, Murphy MB, Seewaldt-Becker E, Koster J. Angiotensin II receptor antagonist telmisartan in isolated systolic hypertension (ARAMIS) study: efficacy and safety of telmisartan 20, 40 or 80 mg versus hydrochlorothiazide 12.5 mg or placebo. Journal of Hypertension 2004;22(5):1033-7.
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Manolis 2004 {published data only} Manolis AJ, Reid JL, de Zeeuw D, Murphy MB, Seewaldt-Becker E, Koster J. Angiotensin II receptor antagonist telmisartan in isolated systolic hypertension (ARAMIS) study: efficacy and safety of telmisartan 20, 40 or 80 mg versus hydrochlorothiazide 12.5 mg or placebo. Journal of Hypertension 2004;22(5):1033-7.
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2001 {published data only} McGill JB. Angiotensin II receptor antagonist plus a thiazide diuretic is more efficacious for treating hypertension than either drug alone
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McGill 2001 {published data only} McGill JB. Angiotensin II receptor antagonist plus a thiazide diuretic is more efficacious for treating hypertension than either drug alone. Blood Pressure Monitoring 2001;6(Suppl 1):S3-S13.
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McGill JB, Reilly PA. Combination treatment with telmisartan and hydrochlorothiazide in black patients with mild to moderate hypertension. Clinical Cardiology 2001;24(1):66-72.
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* McGill JB, Reilly PA. Telmisartan plus hydrochlorothiazide versus telmisartan or hydrochlorothiazide monotherapy in patients with mild to moderate hypertension: A multicenter, randomized, double-blind, placebo-controlled, parallel-group trial. Clinical Therapeutics 2001;23(6):833-50.
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* McGill JB, Reilly PA. Telmisartan plus hydrochlorothiazide versus telmisartan or hydrochlorothiazide monotherapy in patients with mild to moderate hypertension: A multicenter, randomized, double-blind, placebo-controlled, parallel-group trial. Clinical Therapeutics 2001;23(6):833-50.
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Meineke 1997 {published data only} Meineke I, Feltkamp H, Hogemann A, Gundert-Remy U. Pharmacokinetics and pharmacodynamics of candesartan after administration of its pro-drug candesartan cilexitil in patients with mild tomoderate essential hypertension - a population analysis. European Journal of Clinical Pharmacology 1997;53(3-4):221-8.
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Meineke 1997 {published data only} Meineke I, Feltkamp H, Hogemann A, Gundert-Remy U. Pharmacokinetics and pharmacodynamics of candesartan after administration of its pro-drug candesartan cilexitil in patients with mild tomoderate essential hypertension - a population analysis. European Journal of Clinical Pharmacology 1997;53(3-4):221-8.
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Neutel 1998 {published data only} Neutel JM, Smith DHG. Dose response and antihypertensive efficacy of the AT1 receptor antagonist telmisartan in patients with mild to moderate hypertension. Advances in Therapy 1998;15(4):206-17.
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Neutel 1998 {published data only} Neutel JM, Smith DHG. Dose response and antihypertensive efficacy of the AT1 receptor antagonist telmisartan in patients with mild to moderate hypertension. Advances in Therapy 1998;15(4):206-17.
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Neutel 1999 {published data only} Neutel JM, Buckalew v, Chrysant SG, Mroczek WJ, Ruff DA, Weber M. Efficacy and tolerability of tasosartan, a novel angiotensin II receptor blocker: Results from a 10-week, double-blind, placebo-controlled, dose-titration study. American Heart Journal 1999;137 (1):118-25.
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Neutel 1999 {published data only} Neutel JM, Buckalew v, Chrysant SG, Mroczek WJ, Ruff DA, Weber M. Efficacy and tolerability of tasosartan, a novel angiotensin II receptor blocker: Results from a 10-week, double-blind, placebo-controlled, dose-titration study. American Heart Journal 1999;137 (1):118-25.
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Neutel 2002 {published data only} Neutel JM, Elliott WJ, Izzo JL, Chen CL, Masonson HN. Antihypertensive efficacy of olmesartan medoxomil, a new angiotensin II receptor antagonist, as assessed by ambulatory blood pressure measurements. Journal of Clinical Hypertension 2002;4(5):325-31.
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Neutel 2002 {published data only} Neutel JM, Elliott WJ, Izzo JL, Chen CL, Masonson HN. Antihypertensive efficacy of olmesartan medoxomil, a new angiotensin II receptor antagonist, as assessed by ambulatory blood pressure measurements. Journal of Clinical Hypertension 2002;4(5):325-31.
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Oparil 1996 {published data only} Oparil S, Dyke S, Harris F, Kief J, James D, Hester A, Fitzsimmons S. The efficacy and safety of valsartan compared with placebo in the treatment of patients with essential hypertension. Clinical Therapeutics 1996;18(5):797-810.
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Oparil 1996 {published data only} Oparil S, Dyke S, Harris F, Kief J, James D, Hester A, Fitzsimmons S. The efficacy and safety of valsartan compared with placebo in the treatment of patients with essential hypertension. Clinical Therapeutics 1996;18(5):797-810.
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Oparil 1999 {published data only} Oparil S. Eprosartan versus enalapril in hypertensive patients with angiotensin-converting enzyme inhibitor-induced cough. Current Therapeutic Research 1999;60(1):1-14.
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Oparil 1999 {published data only} Oparil S. Eprosartan versus enalapril in hypertensive patients with angiotensin-converting enzyme inhibitor-induced cough. Current Therapeutic Research 1999;60(1):1-14.
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Patterson 2003 {published data only} Patterson D, Webster J, McInnes G, Brady A, MacDonald T. The effects of KT3-671, a new angiotensin II (AT I) receptor blocker in mild to moderate hypertension. British Journal of Clinical Pharmacology 2003;56(5):513-9.
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Patterson 2003 {published data only} Patterson D, Webster J, McInnes G, Brady A, MacDonald T. The effects of KT3-671, a new angiotensin II (AT I) receptor blocker in mild to moderate hypertension. British Journal of Clinical Pharmacology 2003;56(5):513-9.
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Pool 1998 (study 1) {published data only} Pool JL, Guthrie RM, Littlejohn TW, Raskin P, Shephard AMM, Weber MA, Weir MR, Wilson TW, Wright J, Kassler-Taub KB, Reeves RA. Dose-related antihypertensive effects of irbesartan in patients with mild-to-moderate hypertension. American Journal of Hypertension 1998;11(4 Pt 1):462-70.
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Pool 1998 (study 1) {published data only} Pool JL, Guthrie RM, Littlejohn TW, Raskin P, Shephard AMM, Weber MA, Weir MR, Wilson TW, Wright J, Kassler-Taub KB, Reeves RA. Dose-related antihypertensive effects of irbesartan in patients with mild-to-moderate hypertension. American Journal of Hypertension 1998;11(4 Pt 1):462-70.
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Pool 1998 (study 2) {published data only} Pool JL, Guthrie RM, Littlejohn TW, Raskin P, Shephard AMM, Weber MA, Weir MR, Wilson TW, Wright J, Kassler-Taub KB, Reeves RA. Dose-related antihypertensive effects of irbesartan in patients with mild-to-moderate hypertension. American Journal of Hypertension 1998;11(4 Pt 1):462-70.
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Pool 1998 (study 2) {published data only} Pool JL, Guthrie RM, Littlejohn TW, Raskin P, Shephard AMM, Weber MA, Weir MR, Wilson TW, Wright J, Kassler-Taub KB, Reeves RA. Dose-related antihypertensive effects of irbesartan in patients with mild-to-moderate hypertension. American Journal of Hypertension 1998;11(4 Pt 1):462-70.
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Pool 1999 {published data only} Pool JL, Glazer R, Chiang Y-T, Gatlin M. Dose-response efficacy of valsartan, a new angiotensin II receptor blocker. Journal of Human Hypertension 1999;13(4):275-81.
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Pool 1999 {published data only} Pool JL, Glazer R, Chiang Y-T, Gatlin M. Dose-response efficacy of valsartan, a new angiotensin II receptor blocker. Journal of Human Hypertension 1999;13(4):275-81.
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Punzi 2004 {published data only} * Punzi HA, Punzi CF. Once-daily eprosartan mesylate in the treatment of elderly patients with isolated systolic hypertension: data froma 13-week double-blind, placebo-controlled, parallel, multicenter study. Journal of Human Hypertension 2004;18(9):655-61.
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Punzi 2004 {published data only} * Punzi HA, Punzi CF. Once-daily eprosartan mesylate in the treatment of elderly patients with isolated systolic hypertension: data froma 13-week double-blind, placebo-controlled, parallel, multicenter study. Journal of Human Hypertension 2004;18(9):655-61.
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Reif 1998 {published data only} Reif M, White WB, Fagan TC, Oparil S, Flanagan TL, Edwards DT, Cushing DJ, Michelson EL. Effects of candesartan cilexitil in patients with systemic hypertension. American Journal of Cardiology 1998;82(8):961-5.
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Reif 1998 {published data only} Reif M, White WB, Fagan TC, Oparil S, Flanagan TL, Edwards DT, Cushing DJ, Michelson EL. Effects of candesartan cilexitil in patients with systemic hypertension. American Journal of Cardiology 1998;82(8):961-5.
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Smith 2000 {published data only} Smith DHG, Matzek KM, Kempthorne-Rawson J. Dose response and safety of telmisartan in patients with mild to moderate hypertension. Journal of Clinical Pharmacology 2000;40(12 Pt 1):1380-90.
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White 2002 {published data only} White WB, Sica DA, Calhoun D, Mansoor GA, Anders RJ. Preventing increases in early-morning blood pressure, heart rate, and the rate-pressure product with controlled onset extended release verapamil at bedtime versus enalapril, losartan, and placebo on arising. American Heart Journal 2002;144(4):657-65.
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Bakris 2002 {published data only} Bakris G, Sica D, Ram V, Fagan T, Vaitkus PT, Anders RJ, et al.A comparative trial of controlled-onset, extended-release verapamil, enalapril, and losartan on blood pressure and heart rate changes. American Journal of Hypertension 2002;15(1 Pt 1):53-7.
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Koh 2004 {published data only} * Koh KK, Chung WJ, Ahn JY, Han SH, Kang WC, Seo YH, et al.Angiotensin II type 1 receptor blockers reduce tissue factor activity and plasminogen activator inhibitor type-1 antigen in hypertensive patients: a randomized, double-blind, placebo-controlled study. Atherosclerosis 2004;177(1):155-60.
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Marino 1999 {published data only} Marino MR, Langenbacher KM, Ford NF, Raymond RH, Manning J, Vesterqvist O, et al.Pharmacodynamics and pharmacokinetics of irbesartan in patients with mild to moderate hypertension. Journal of Cardiovascular Pharmacology & Therapeutics 1999;4(2):67-75.
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Neutel 1997 {published data only} Neutel J, Weber M, Pool J, Smith D, Fitzsimmons S, Chiang YT, et al.Valsartan, a new angiotensin II antagonist: antihypertensive effects over 24 hours. Clinical Therapeutics 1997;19(3):447-58.
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Petrov 2001 {published data only} Petrov VV, Fagard RH, Lijnen PJ. T-lymphocyte and plasma angiotensin-converting enzyme activity during enalapril and losartan administration in humans. Journal of Cardiovascular Pharmacology 2001;38(4):578-83.
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