Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children

Cochrane Database of Systematic Reviews

Volumn , Issue 3, 2008, Pages

  Appleton, Richard ^a   Macleod, Stewart ^a   Martland, Timothy ^b  

^a ALDER HEY CHILDREN S HOSPITAL   (United Kingdom)

^b ROYAL MANCHESTER CHILDREN S HOSPITAL   (United Kingdom)

Author keywords

Administration, rectal; Anticonvulsants *therapeutic use ; Diazepam administration dosage ; Epilepsy, tonic clonic *drug therapy ; Injections, intravenous; Lorazepam administration dosage

Indexed keywords

ANTICONVULSIVE AGENT; DIAZEPAM; LORAZEPAM; MIDAZOLAM; PARALDEHYDE; PHENOBARBITAL; PHENYTOIN;

CLINICAL TRIAL; COCHRANE LIBRARY; DATA ANALYSIS; DRUG EFFICACY; DRUG SAFETY; EMBASE; EPILEPTIC STATE; FEBRILE CONVULSION; HOSPITAL; HUMAN; INFORMATION PROCESSING; MEDLINE; OUTCOME ASSESSMENT; QUASI EXPERIMENTAL STUDY; RANDOMIZED CONTROLLED TRIAL; RESPIRATION DEPRESSION; REVIEW; SEIZURE; SINGLE DRUG DOSE; SYSTEMATIC REVIEW; TONIC CLONIC SEIZURE;

EID: 55049128607     PISSN: 1469493X     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD001905.pub2     Document Type: Review

References (11)

1. Ahmad 2006 {published data only} * Ahmad S, Ellis JC, Kamwendo H, Molyneux E. Efficacy and safety of intranasal lorazepam versus intramuscular paraldehyde for protracted convulsions in children: an open randomised trial. Lancet 2006;367:1591-7.
2. Appleton 1995 {published data only} * Appleton RE, Sweeney A, Choonara I, Robson J, Molyneux E. Lorazepam versus diazepam in the acute treatment of epileptic seizures and status epilepticus. Developmental Medicine and Child Neurology 1995;37:682-8.
3. Lahat 2000 {published data only} * Lahat E, Goldman M, Barr J, Bistritzer T, Berkovitch M. Comparison of intranasal midazolam with intravenous diazepam for treating febrile seizures in children: prospective randomised study. British Medical Journal 2000;321:83-6.
4. McIntyre 2005 {published data only} McIntyre J, Robertson S, Norris E, Appleton RE, Whitehouse WP, Phillips B, et al. Safety and efficacy of buccal midazolam versus rectal diazepam for emergency treatment of seizures in children: a randomised controlled trial. Lancet 2005;366(9481): 205-10.
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7. Dodson 1993 Dodson WE, De Lorenzo RJ, Pedley TA et al for the Epilepsy Foundation of America's Working Group on Status Epilepticus. Treatment of convulsive status epilepticus. Journal of the American Medical Association 1993;270:854.
8. Garr 1999 Garr RE, Appleton RE, Robson WJ, Molyneux EM. Children presenting with convulsions (including status epilepticus) to a paediatric accident and emergency department: an audit of a treatment protocol. Developmental Medicine and Child Neurology 1999;41:44-7.
9. Martland 1998 Martland T, Baxter P, Rittey C. Is there an agreed treatment for children in status epilepticus?. Developmental Medicine and Child Neurology 1998;40:286-7.
10. Shorvon 1993 Shorvon S. Status epilepticus; its clinical features and treatment in adults and children. Cambridge: Cambridge University Press, 1993.
11. Working Party 2000 The Status Epilepticus Working Party. The treatment of convulsive status epilepticus in children. Archives of Disease in Childhood 2000;83:415-9.