Cytokine levels in pleural effusions of patients under intensive care

Journal of Nippon Medical School

Volumn 75, Issue 5, 2008, Pages 262-268

  Shirakabe, Akihiro ^a,b   Hata, Noritake ^a,b   Yokoyama, Shinya ^a,b   Shinada, Takuro ^a,b   Suzuki, Yuuichirou ^a,b   Kobayashi, Nobuaki ^a,b   Kikuchi, Arifumi ^a,b   Takano, Teruo ^b   Mizuno, Kyoichi ^b  

^a NIPPON MEDICAL SCHOOL CHIBA HOKUSOH HOSPITAL   (Japan)

^b NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Cytokine; Inflammation; Interleukin 10; Interleukin 6; Pleural effusion; Tumor necrosis factor

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

AGED; ARTICLE; BODY TEMPERATURE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; INTENSIVE CARE UNIT; LEUKOCYTE COUNT; MALE; PLEURA EFFUSION; PNEUMONIA; THORACOCENTESIS;

AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; EXUDATES AND TRANSUDATES; FEMALE; HUMANS; INFLAMMATION MEDIATORS; INTENSIVE CARE; INTERLEUKIN-10; INTERLEUKIN-6; MALE; PLEURAL EFFUSION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 55049105218     PISSN: 13454676     EISSN: 13473409     Source Type: Journal    
DOI: 10.1272/jnms.75.262     Document Type: Article

References (37)

1. Jean-Baptiste E: Cellular mechanisms in sepsis. J Intensive Care Med 2007; 22: 63-72.
2. Nijsten MW, de Groot ER, ten Duis HJ, Klasen HJ, Hack CE, Aarden LA: Serum levels of interleukin-6 and acute phase responses. Lancet 1987; 2: 921.
3. Song M, Kellum JA: Interleukin-6. Crit Care Med 2005; 33: S463-S465.
4. Clark IA: How TNF was recognized as a key mechanism of disease. Cytokine Growth Factor Rev 2007; 18: 335-343.
5. Akarsu S, Kurt AN, Dogan Y, Yilmaz E, Godekmerdan A, Aygun AD: The differential diagnostic values of cytokine levels in pleural effusions. Mediators Inflamm 2005; 2005: 2-8.
6. Porcel JM, Vives M, Esquerda A: Tumor necrosis factor-alpha in pleural fluid: a marker of complicated parapneumonic effusions. Chest 2004; 125: 160-164.
7. Diao H, Kohanawa M: Endogenous interleukin-6 plays a crucial protective role in streptococcal toxic shock syndrome via suppression of tumor necrosis factor alpha production. Infect Immun 2005; 73: 3745-3748.
8. Light RW, Macgregor MI, Luchsinger PC, Ball WC Jr: Pleural effusions: the diagnostic separation of transudates and exudates. Ann Intern Med 1972; 77: 507-513.
9. Hsieh CC, Tang RB, Tsai CH, Chen W: Serum interleukin-6 and tumor necrosis factor-alpha concentrations in children with mycoplasma pneumonia. J Microbiol Immunol Infect 2001; 34: 109-112.
10. Makhija P, Yadav S, Thakur A: Tumor necrosis factor alpha and interleukin 6 in infants with sepsis. Indian Pediatr 2005; 42: 1024-1028.
11. Nishimoto N, Yoshizaki K, Tagoh H, Monden M, Kishimoto S, Hirano T, Kishimoto T: Elevation of serum interleukin 6 prior to acute phase proteins on the inflammation by surgical operation. Clin Immunol Immunopathol 1989; 50: 399-401.
12. Biasucci LM, Vitelli A, Liuzzo G, et al.: Elevated levels of interleukin-6 in unstable angina. Circulation 1996; 94: 874-877.
13. Ferroni P, Rosa A, Di Franco M, et al.: Prognostic significance of interleukin-6 measurement in the diagnosis of acute myocardial infarction in emergency department. Clin Chim Acta 2007; 381: 151-156.
14. Debrunner M, Schuiki E, Minder E, et al.: Proinflammatory cytokines in acute myocardial infarction with and without cardiogenic shock. Clin Res Cardiol 2008; 97: 298-305.
15. Suzuki H, Kusuyama T, Sato R, et al.: Elevation of matrix metalloproteinases and interleukin-6 in the culprit coronary artery of myocardial infarction. Eur J Clin Invest 2008; 38: 166-173.
16. Levine B, Kalman J, Mayer L, Fillit HM, Packer M: Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med 1990; 323: 236-241.
17. MacGowan GA, Mann DL, Kormos RL, Feldman AM, Murali S: Circulating interleukin-6 in severe heart failure. Am J Cardiol 1997; 79: 1128-1131.
18. Suzuki H, Sato R, Sato T, et al.: Time-course of changes in the levels of interleukin 6 in acutely decompensated heart failure. Int J Cardiol 2005; 100: 415-420.
19. Peschel T, Schonauer M, Thiele H, Anker SD, Schuler G, Niebauer J: Invasive assessment of bacterial endotoxin and inflammatory cytokines in patients with acute heart failure. Eur J Heart Fail 2003; 5: 609-614
20. Chen D, Assad-Kottner C, Orrego C, Torre-Amione G: Cytokines and acute heart failure. Crit Care Med 2008; 36: S9-16.
21. Alexandrakis MG, Coulocheri SA, Bouros D, Mandalaki K, Karkavitsas N, Eliopoulos GD: Evaluation of inflammatory cytokines in malignant and benign pleural effusions. Oncol Rep 2000; 7: 1327-1332.
22. Houssiau FA, Devogelaer JP, Van Damme J, de Deuxchaisnes CN, Van Snick J: Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides. Arthritis Rheum 1988; 31: 784-788.
23. Waage A, Kaufmann C, Espevik T, Husby G: Interleukin-6 in synovial fluid from patients with arthritis. Clin Immunol Immunopathol 1989; 50: 394-398.
24. Houssiau FA, Bukasa K, Sindic CJ, Van Damme J, Van Snick J: Elevated levels of the 26K human hybridoma growth factor (interleukin 6) in cerebrospinal fluid of patients with acute infection of the central nervous system. Clin Exp Immunol 1988; 71: 320-323.
25. Yokoyama A, Maruyama M, Ito M, Kohno N, Hiwada K, Yano S: Interleukin 6 activity in pleural effusion. Its diagnostic value and thrombopoietic activity. Chest 1992; 102: 1055-1059.
26. Xirouchaki N, Tzanakis N, Bouros D, et al.: Diagnostic value of interleukin-1alpha, interleukin-6, and tumor necrosis factor in pleural effusions. Chest 2002; 121: 815-820.
27. Shimokata K, Saka H, Murate T, Hasegawa Y, Hasegawa T: Cytokine content in pleural effusion. Comparison between tuberculous and carcinomatous pleurisy. Chest 1991; 99: 1103-1107.
28. Herbein G, O'Brien WA: Tumor necrosis factor (TNF)-alpha and TNF receptors in viral pathogenesis. Proc Soc Exp Biol Med 2000; 223: 241-257.
29. Odeh M, Makhoul B, Sabo E, Srugo I, Oliven A: The role of pleural fluid-serum gradient of tumor necrosis factor-alpha concentration in discrimination between complicated and uncomplicated parapneumonic effusion. Lung 2005; 183: 13-27.
30. Coker RK, Laurent GJ: Pulmonary fibrosis: cytokines in the balance. Eur Respir J 1998; 11: 1218-1221.
31. Chung CL, Chen YC, Chang SC: Effect of repeated thoracenteses on fluid characteristics, cytokines, and fibrinolytic activity in malignant pleural effusion. Chest 2003; 123: 1188-1195.
32. Chomej P, Bauer K, Bitterlich N, et al.: Differential diagnosis of pleural effusions by fuzzy-logic-based analysis of cytokines. Respir Med 2004; 98: 308-317.
33. Hoheisel G, Izbicki G, Roth M, et al.: Proinflammatory cytokine levels in patients with lung cancer and carcinomatous pleurisy. Respiration 1998; 65: 183-186.
34. Kim YC, Park KO, Bom HS, et al.: Combining ADA, protein and IFN-gamma best allows discrimination between tuberculous and malignant pleural effusion. Korean J Intern Med 1997; 12: 225-231.
35. Chen YM, Yang WK, Whang-Peng J, Kuo BI, Perng RP: Elevation of interleukin-10 levels in malignant pleural effusion. Chest 1996; 110: 433-436.
36. Chen YM, Yang WK, Ting CC, et al.: Cross regulation by IL-10 and IL-2/IL-12 of the helper T cells and the cytolytic activity of lymphocytes from malignant effusions of lung cancer patients. Chest 1997; 112: 960-966.
37. Chen YM, Yang WK, Whang-Peng J, Tsai CM, Perng RP: An analysis of cytokine status in the serum and effusions of patients with tuberculous and lung cancer. Lung Cancer 2001; 31: 25-30.