Loss of heterozygosity at chromosome 14q is associated with poor prognosis in head and neck squamous cell carcinomas

Journal of Cancer Research and Clinical Oncology

Volumn 134, Issue 12, 2008, Pages 1267-1276

  Pehlivan, Davut ^a,c   Gunduz, Esra ^a   Gunduz, Mehmet ^a,b   Nagatsuka, Hitoshi ^a   Beder, Levent Bekir ^b   Cengiz, Beyhan ^a   Rivera, Rosario S ^a   Fukushima, Kunihiro ^a   Palanduz, Sukru ^c   Ozturk, Sukru ^c   Yamanaka, Noboru ^b   Shimizu, Kenji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^c ISTANBUL UNIVERSITY   (Turkey)

Author keywords

14q; D14S67; D14S995; Head and neck squamous cell carcinoma; Loss of heterozygosity; Microsatellite marker; Survival

Indexed keywords

ADULT; AGED; ARTICLE; CANCER SURVIVAL; CHROMOSOME 14Q; CLINICAL FEATURE; DISEASE FREE SURVIVAL; FEMALE; GENE DELETION; HEAD AND NECK CARCINOMA; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MALE; MICROSATELLITE MARKER; NUCLEOTIDE SEQUENCE; OVERALL SURVIVAL; PATHOLOGY; POLYMORPHIC LOCUS; PRIORITY JOURNAL; PROGNOSIS; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE; SURVIVAL TIME;

AGED; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; CHROMOSOME DELETION; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 14; FEMALE; GENES, TUMOR SUPPRESSOR; HEAD AND NECK NEOPLASMS; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; PROGNOSIS; SURVIVAL RATE;

EID: 54949157602     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-008-0423-1     Document Type: Article

References (32)

1. T Bando Y Kato Y Ihara F Yamagishi K Tsukada M Isobe 1999 Loss of heterozygosity of 14q32 in colorectal carcinoma Cancer Genet Cytogenet 111 161 165 10.1016/S0165-4608(98) 00242-8
2. LB Beder M Gunduz M Ouchida K Fukushima E Gunduz S Ito 2003 Genome-wide analyses on loss of heterozygosity in head and neck squamous cell carcinomas Lab Invest 83 99 105
3. L Cardone A Carlucci A Affaitati A Livigni T DeCristofaro C Garbi 2004 Mitochondrial AKAP121 binds and targets protein tyrosine phosphatase D1, a novel positive regulator of src signaling Mol Cell Biol 24 4613 4626 10.1128/MCB.24.11.4613-4626.2004
4. B Cengiz M Gunduz H Nagatsuka L Beder E Gunduz R Tamamura 2007 Fine deletion mapping of chromosome 2q21-37 shows three preferentially deleted regions in oral cancer Oral Oncol 43 241 247 10.1016/j.oraloncology.2006.03.004
5. JT Chang HM Wang KW Chang WH Chen MC Wen YM Hsu 2005 Identification of differentially expressed genes in oral squamous cell carcinoma (OSCC): overexpression of NPM, CDK1 and NDRG1 and underexpression of CHES1 Int J Cancer 114 942 949 10.1002/ijc.20663
6. CM Croce 1991 Genetic approaches to the study of the molecular basis of human cancer Cancer Res 51 5015s 5018s
7. A De Rienzo SC Jhanwar JR Testa 2000 Loss of heterozygosity analysis of 13q and 14q in human malignant mesothelioma Genes Chromosomes Cancer 28 337 341 10.1002/1098-2264(200007)28:3<337::AID-GCC12>3.0.CO;2-B
8. W El-Rifai M Sarlomo-Rikala LC Andersson M Miettinen S Knuutila 2000 High-resolution deletion mapping of chromosome 14 in stromal tumors of the gastrointestinal tract suggests two distinct tumor suppressor loci Genes Chromosomes Cancer 27 387 391 10.1002/(SICI) 1098-2264(200004) 27:4<387::AID-GCC8>3.0.CO;2-C
9. M Gunduz M Ouchida K Fukushima H Hanafusa T Etani S Nishioka 2000 Genomic structure of the human ING1 gene and tumor-specific mutations detected in head and neck squamous cell carcinomas Cancer Res 60 3143 3146
10. M Gunduz M Ouchida K Fukushima S Ito Y Jitsumori T Nakashima 2002 Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers Oncogene 21 4462 4470 10.1038/sj.onc. 1205540
11. M Gunduz H Nagatsuka K Demircan E Gunduz B Cengiz M Ouchida 2005 Frequent deletion and down-regulation of ING4, a candidate tumor suppressor gene at 12p13, in head and neck squamous cell carcinomas Gene 356 109 117 10.1016/j.gene.2005.02.014
12. K Harvey N Tapon 2007 The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network Nat Rev Cancer 7 182 191 10.1038/nrc2070
13. J Herbers D Schullerus H Muller C Kenck J Chudek J Weimer 1997 Significance of chromosome arm 14q loss in nonpapillary renal cell carcinomas Genes Chromosomes Cancer 19 29 35 10.1002/(SICI) 1098-2264(199705) 19:1<29::AID-GCC5>3.0.CO;2-2
14. M Hoshi N Otagiri HO Shiwaku S Asakawa N Shimizu Y Kaneko 2000 Detailed deletion mapping of chromosome band 14q32 in human neuroblastoma defines a 1.1-Mb region of common allelic loss Br J Cancer 82 1801 1807 10.1054/bjoc.2000.1108
15. A Jemal R Siegel E Ward T Murray J Xu C Smigal 2006 Cancer statistics, 2006 CA Cancer J Clin 56 106 130
16. HY Jui RJ Tseng X Wen HI Fang LM Huang KY Chen 2000 Protein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinases J Biol Chem 275 41124 41132 10.1074/jbc.M007772200
17. DJ Lee WM Koch G Yoo M Lango A Reed J Califano 1997 Impact of chromosome 14q loss on survival in primary head and neck squamous cell carcinoma Clin Cancer Res 3 501 505
18. X Li NK Lee YW Ye PG Waber C Schweitzer QC Cheng 1994 Allelic loss at chromosomes 3p, 8p, 13q, and 17p associated with poor prognosis in head and neck cancer J Natl Cancer Inst 86 1524 1529 10.1093/jnci/86.20.1524
19. ML Lung CV Choi H Kong PW Yuen D Kwong J Sham 2001 Microsatellite allelotyping of chinese nasopharyngeal carcinomas Anticancer Res 21 3081 3084
20. WM Lydiatt BJ Davidson SP Schantz S Caruana RS Chaganti 1998 9p21 deletion correlates with recurrence in head and neck cancer Head Neck 20 113 118 10.1002/(SICI) 1097-0347(199803) 20:2<113::AID-HED3>3.0.CO;2-5
21. K Mitsumori JM Kittleson N Itoh B Delahunt RW Heathcott JH Stewart 2002 Chromosome 14q LOH in localized clear cell renal cell carcinoma J Pathol 198 110 114 10.1002/path.1165
22. TG Nishanian JS Kim A Foxworth T Waldman 2004 Suppression of tumorigenesis and activation of Wnt signaling by bone morphogenetic protein 4 in human cancer cells Cancer Biol Ther 3 667 675
23. DM Parkin F Bray J Ferlay P Pisani 2005 Global cancer statistics, 2002 CA Cancer J Clin 55 74 108
24. Z Piao C Park JH Park H Kim 1998 Allelotype analysis of hepatocellular carcinoma Int J Cancer 75 29 33 10.1002/(SICI)1097-0215(19980105)75:1<29:: AID-IJC5>3.0.CO;2-3
25. DT Ransom TC Barnett J Bot B de Boer C Metcalf JA Davidson 1998 Loss of heterozygosity on chromosome 2q: possibly a poor prognostic factor in head and neck cancer Head Neck 20 404 410 10.1002/(SICI) 1097-0347(199808) 20:5<404::AID-HED8>3.0.CO;2-1
26. KL Scott SE Plon 2003 Loss of Sin3/Rpd3 histone deacetylase restores the DNA damage response in checkpoint-deficient strains of Saccharomyces cerevisiae Mol Cell Biol 23 4522 4531 10.1128/MCB.23.13.4522-4531.2003
27. KL Scott SE Plon 2005 CHES1/FOXN3 interacts with Ski-interacting protein and acts as a transcriptional repressor Gene 359 119 126 10.1016/j.gene.2005.06. 014
28. Y Shi P Ouyang SP Sugrue 2000 Characterization of the gene encoding pinin/DRS/memA and evidence for its potential tumor suppressor function Oncogene 19 289 297 10.1038/sj.onc.1203328
29. M Simon A von Deimling JJ Larson R Wellenreuther P Kaskel A Waha 1995 Allelic losses on chromosomes 14, 10 and 1 in atypical and malignant meningiomas: a genetic model of meningioma progression Cancer Res 55 4696 4701
30. T Tiganis AM Bennett 2007 Protein tyrosine phosphatase function: the substrate perspective Biochem J 402 1 15 10.1042/BJ20061548
31. EM Whitney AM Ghaleb X Chen VW Yang 2006 Transcriptional profiling of the cell cycle checkpoint gene krüppel-like factor 4 reveals a global inhibitory function in macromolecular biosynthesis Gene Expr 13 85 96 10.3727/000000006783991908
32. W Yan L Song W Wei A Li J Liu Y Fang 2005 Chromosomal abnormalities associated with neck nodal metastasis in nasopharyngeal carcinoma Tumour Biol 26 306 312 10.1159/000089289