Verapamil inhibits L-type calcium channel mediated apoptosis in human colon cancer cells

Diseases of the Colon and Rectum

Volumn 51, Issue 11, 2008, Pages 1696-1702

  Zawadzki, Antoni ^a   Liu, Qing ^a   Wang, Yusheng ^a   Melander, Arne ^a,b   Jeppsson, Bengt ^a   Thorlacius, Henrik ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b Network for Pharmacoepidemiology Foundation   (Sweden)

Author keywords

Apoptosis; Colon cancer; Intestine; Verapamil

Indexed keywords

BAYK 8644; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL STIMULATING AGENT; CALCIUM ION; MESSENGER RNA; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; VERAPAMIL;

AGED; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CANCER CELL CULTURE; COLON CANCER; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG INHIBITION; FEMALE; FLOW CYTOMETRY; FLUOROMETRY; HUMAN; HUMAN CELL; INCUBATION TIME; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

3-PYRIDINECARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-(TRIFLUOROMETHYL)PHENYL)-, METHYL ESTER; APOPTOSIS; CALCIUM CHANNEL AGONISTS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; COLONIC NEOPLASMS; HUMANS; RNA, MESSENGER; VERAPAMIL;

EID: 54949157133     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1007/s10350-008-9372-7     Document Type: Article

References (40)

1. M Pahor JM Guralnik L Ferrucci 1996 Calcium-channel blockade and incidence of cancer in aged populations Lancet 348 493 497
2. M Pahor A Manto C Pedone L Carosella JM Guralnik P Carbonin 1996 Age and severe adverse drug reactions caused by nifedipine and verapamil. Gruppo Italiano di Farmacovigilanza nell' Anziano (GIFA) J Clin Epidemiol 49 921 928
3. CD Furberg M Pahor BM Psaty 1996 The unnecessary controversy Eur Heart J 17 1142 1147
4. L Hardell O Axelson M Fredrikson 1996 Antihypertensive drugs and risk of malignant diseases Lancet 348 542
5. LH Lindholm H Anderson T Ekbom 2001 Relation between drug treatment and cancer in hypertensives in the Swedish trial in old patients with hypertension 2: a 5-year, prospective, randomized, controlled trial Lancet 358 539 544
6. ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group 2002 Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) JAMA 288 2981 2997
7. JF Whitfield 1992 Calcium signals and cancer Crit Rev Oncol 3 55 90
8. MJ Berridge MD Bootman P Lipp 1998 Calcium-a life and death signal Nature 395 645 648
9. MD Bootman TJ Collins CM Peppiatt 2001 Calcium signaling-an overview Semin Cell Dev Biol 12 3 10
10. J Striessnig 1999 Pharmacology, structure and function of cardiac L-type Ca(2+) channels Cell Physiol Biochem 9 242 269
11. E Perez-Reyes T Schneider 1995 Molecular biology of calcium channels Kidney Int 48 1111 1124
12. L Zhang W Zhou VE Velculescu 1997 Gene expression profiles in normal and cancer cells Science 276 1268 1272
13. XT Wang Y Nagaba HS Cross F Wrba L Zhang SE Guggino 2000 The mRNA of L-type calcium channel elevated in colon cancer: protein distribution in normal and cancerous colon Am J Pathol 157 1549 1562
14. LH Opie FR Buhler A Fleckenstein 1987 International society and federation of cardiology: working group on classification of calcium antagonists for cardiovascular disease Am J Cardiol 60 630 632
15. SW Jones 1998 Overview of voltage-dependent calcium channels J Bioenerg Biomembr 30 299 312
16. A Baten K Sakamoto AM Shamsuddin 1992 Long-term culture of normal human colonic epithelial cells in vitro FASEB J 6 2726 2734
17. AN Corps KD Brown 1987 Stimulation of intestinal epithelial cell proliferation in culture by growth factors in human and ruminant mammary secretions J Endocrinol 113 285 290
18. CN Conteas B McMorrow GD Luk 1989 Modulation of epidermal growth factor-induced cell proliferation and receptor binding by insulin in cultured intestinal epithelial cells Biochem Biophys Res Commun 161 414 419
19. N Pandis S Heim G Bardi J Limon N Mandahl F Mitelman 1992 Improved technique for short-term culture and cytogenetic analysis of human breast cancer Genes Chromosomes Cancer 5 14 20
20. GS Evans N Flint CS Potten 1994 Primary cultures for studies of cell regulation and physiology in intestinal epithelium Annu Rev Physiol 56 399 417
21. EL Barry 2000 Expression of mRNAs for the alpha 1 subunit of voltage-gated calcium channels in human osteoblast-like cell lines and in normal human osteoblasts Calcif Tissue Int 66 145 150
22. BJ Sheppard M Williams HK Plummer HM Schuller 2000 Activation of voltage-operated Ca2 + channels in human small cell lung carcinoma by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone Int J Oncol 16 513 518
23. G Koopman CP Reutelingsperger GA Kuijten RM Keehnen ST Pals MH van Oers 1994 Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis Blood 84 1415 1420
24. M van Engeland FC Ramaekers B Schutte CP Reutelingsperger 1996 A novel assay to measure loss of plasma membrane asymmetry during apoptosis of adherent cells in culture Cytometry 24 131 139
25. WA Catterall E Perez-Reyes TP Snutch J Striessnig 2005 International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels Pharmacol Rev 57 411 425
26. MJ Wargovich PH Lointier 1987 Calcium and vitamin D modulate mouse colon epithelial proliferation and growth characteristics of a human colon tumor cell line Can J Physiol Pharmacol 65 472 477
27. BF Trump IK Berezesky 1995 Calcium-mediated cell injury and cell death FASEB J 9 219 228
28. R Adell-Carceller M Segarra-Soria J Gibert-Jerez 1997 Inhibitory effect of calcium on carcinogenesis at the site of colonic anastomosis: an experimental study Dis Colon Rectum 40 1376 1381
29. E Kallay E Bajna F Wrba S Kriwanek M Peterlik HS Cross 2000 Dietary calcium and growth modulation of human colon cancer cells: role of the extracellular calcium-sensing receptor Cancer Detect Prev 24 127 136
30. R Jarvinen P Knekt T Hakulinen A Aromaa 2001 Prospective study on milk products, calcium and cancers of the colon and rectum Eur J Clin Nutr 55 1000 1007
31. K Wu WC Willett CS Fuchs GA Colditz EL Giovannucci 2002 Calcium intake and risk of colon cancer in women and men J Natl Cancer Inst 94 437 446
32. KK Carroll 1996 Dietary fats and cancer Am J Clin Nutr 53 S1064 S1067
33. MJ Wargovich 1992 Fish oil and colon cancer Gastroenterology 103 1096 1098
34. DP Rose JM Connolly 1999 Omega-3 fatty acids as cancer chemopreventive agents Pharmacol Ther 83 217 244
35. TE DeCoursey 1995 Mechanism of K+ channel block by verapamil and related compounds in rat alveolar epithelial cells J Gen Physiol 106 745 779
36. TE DeCoursey KG Chandy S Gupta MD Cahalan 1985 Voltage-dependent ion channels in T-lymphocytes J Neuroimmunol 10 71 95
37. M Jonas U Goldbourt V Boyko L Mandelzweig S Behar H Reicher-Reiss 1998 Nifedipine and cancer mortality: ten-year follow-up of 2607 patients after acute myocardial infarction Cardiovasc Drugs Ther 12 177 181
38. KB Michels BA Rosner AM Walker 1998 Calcium channel blockers, cancer incidence, and cancer mortality in a cohort of U.S. women: the nurses' health study Cancer 83 2003 2007
39. K Kanamasa A Kimura M Miyataka T Takenaka K Ishikawa 1999 Incidence of cancer in postmyocardial infarction patients treated with short-acting nifedipine and diltiazem. Secondary Prevention Group Cancer 85 1369 1374
40. A Sajadieh HH Storm JF Hansen 1999 Verapamil and risk of cancer in patients with coronary artery disease. DAVIT Study Group. Danish Verapamil Infarction Trial Am J Cardiol 83 1419 1422