S163 is critical for FXYD5 modulation of wound healing in airway epithelial cells

Wound Repair and Regeneration

Volumn 16, Issue 6, 2008, Pages 791-799

  Miller, Timothy J ^a   Davis, Pamela B ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); DYSADHERIN; GLYCOPROTEIN; MUTANT PROTEIN; S163 PROTEIN; SERINE; UNCLASSIFIED DRUG; VIMENTIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MIGRATION; CELL MOTILITY; CELL POLARITY; CELL STRAIN HEK293; EMBRYO; EPITHELIUM CELL; EPITHELIZATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; IN VITRO STUDY; MOLECULAR CLOCK; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; RESPIRATORY EPITHELIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; WILD TYPE; WOUND HEALING;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; EPITHELIAL CELLS; MEMBRANE GLYCOPROTEINS; MICE; MUTATION; NEOPLASM PROTEINS; RESPIRATORY MUCOSA; SODIUM-POTASSIUM-EXCHANGING ATPASE; WOUND HEALING;

EID: 54949139960     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/j.1524-475X.2008.00432.x     Document Type: Article

References (39)

1. Chifflet S, Hernandez JA, Grasso S. A possible role for membrane depolarization in epithelial wound healing. Am J Physiol Cell Physiol 2005 288 : C1420 30.
2. Xie Z. Membrane transporters and signal transduction. Cell Mol Biol (Noisy-le-grand) 2006 52 : 1 2.
3. Xie Z, Askari A. Na(+)/K(+)-ATPase as a signal transducer. Eur J Biochem 2002 269 : 2434 9.
4. Barwe SP, Kim S, Rajasekaran SA, Bowie JU, Rajasekaran AK. Janus model of the Na,K-ATPase beta-subunit transmembrane domain: distinct faces mediate alpha/beta assembly and beta-beta homo-oligomerization. J Mol Biol 2007 365 : 706 14.
5. Rajasekaran SA, Barwe SP, Rajasekaran AK. Multiple functions of Na,K-ATPase in epithelial cells. Semin Nephrol 2005 25 : 328 34.
6. Barwe SP, Anilkumar G, Moon SY, Zheng Y, Whitelegge JP, Rajasekaran SA, Rajasekaran AK. Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility. Mol Biol Cell 2005 16 : 1082 94.
7. Rajasekaran SA, Palmer LG, Quan K, Harper JF, Ball WJ Jr., Bander NH, Peralta Soler A, Rajasekaran AK. Na,K-ATPase beta-subunit is required for epithelial polarization, suppression of invasion, and cell motility. Mol Biol Cell 2001 12 : 279 95.
8. Sweadner KJ, Rael E. The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression. Genomics 2000 68 : 41 56.
9. Batistatou A, Peschos D, Tsanou H, Charalabopoulos A, Nakanishi Y, Hirohashi S, Agnantis NJ, Charalabopoulos K. In breast carcinoma dysadherin expression is correlated with invasiveness but not with E-cadherin. Br J Cancer 2007 96 : 1404 8.
10. Shimamura T, Yasuda J, Ino Y, Gotoh M, Tsuchiya A, Nakajima A, Sakamoto M, Kanai Y, Hirohashi S. Dysadherin expression facilitates cell motility and metastatic potential of human pancreatic cancer cells. Cancer Res 2004 64 : 6989 95.
11. +-ATPase in colorectal cancer cells. Biol Pharm Bull 2007 30 : 648 54.
12. Ino Y, Gotoh M, Sakamoto M, Tsukagoshi K, Hirohashi S. Dysadherin, a cancer-associated cell membrane glycoprotein, down-regulates E-cadherin and promotes metastasis. Proc Natl Acad Sci USA 2002 99 : 365 70.
13. Miller TJ, Davis PB. FXYD5 modulates Na+ absorption and is increased in cystic fibrosis airway epithelia. Am J Physiol Lung Cell Mol Physiol 2008 294 : L654 64.
14. Konstan MW, Davis PB, Wagener JS, Hilliard KA, Stern RC, Milgram LJ, Kowalczyk TH, Hyatt SL, Fink TL, Gedeon CR, Oette SM, Payne JM, Muhammad O, Ziady AG, Moen RC, Cooper MJ. Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator reconstitution. Hum Gene Ther 2004 15 : 1255 69.
15. Lubarski I, Pihakaski-Maunsbach K, Karlish SJ, Maunsbach AB, Garty H. Interaction with the Na,K-ATPase and tissue distribution of FXYD5 (related to ion channel). J Biol Chem 2005 280 : 37717 24.
16. Garty H, Karlish SJ. Role of FXYD proteins in ion transport. Annu Rev Physiol 2006 68 : 431 59.
17. Mahmmoud YA, Vorum H, Cornelius F. Identification of a phospholemman-like protein from shark rectal glands. Evidence for indirect regulation of Na,K-ATPase by protein kinase c via a novel member of the FXYDY family. J Biol Chem 2000 275 : 35969 77.
18. Arystarkhova E, Donnet C, Munoz-Matta A, Specht SC, Sweadner KJ. Multiplicity of expression of FXYD proteins in mammalian cells: dynamic exchange of phospholemman and gamma-subunit in response to stress. Am J Physiol Cell Physiol 2007 292 : C1179 91.
19. Mandal M, Myers JN, Lippman SM, Johnson FM, Williams MD, Rayala S, Ohshiro K, Rosenthal DI, Weber RS, Gallick GE, El-Naggar AK. Epithelial to mesenchymal transition in head and neck squamous carcinoma: association of Src activation with E-cadherin down-regulation, vimentin expression, and aggressive tumor features. Cancer 2008 112 : 2088 100.
20. Wei J, Xu G, Wu M, Zhang Y, Li Q, Liu P, Zhu T, Song A, Zhao L, Han Z, Chen G, Wang S, Meng L, Zhou J, Lu Y, Wang S, Ma D. Overexpression of vimentin contributes to prostate cancer invasion and metastasis via src regulation. Anticancer Res 2008 28 (1A) : 327 34.
21. Rajasekaran AK, Gopal J, Rajasekaran SA. Na,K-ATPase in the regulation of epithelial cell structure. Ann NY Acad Sci 2003 986 : 649 51.
22. Rajasekaran AK, Rajasekaran SA. Role of Na-K-ATPase in the assembly of tight junctions. Am J Physiol Renal Physiol 2003 285 : F388 96.
23. Rajasekaran SA, Palmer LG, Moon SY, Peralta Soler A, Apodaca GL, Harper JF, Zheng Y, Rajasekaran AK. Na,K-ATPase activity is required for formation of tight junctions, desmosomes, and induction of polarity in epithelial cells. Mol Biol Cell 2001 12 : 3717 32.
24. Rajasekaran SA, Gopal J, Rajasekaran AK. Expression of Na,K-ATPase beta-subunit in transformed MDCK cells increases the translation of the Na,K-ATPase alpha-subunit. Ann NY Acad Sci 2003 986 : 652 4.
25. Garty H, Lindzen M, Scanzano R, Aizman R, Füzesi M, Goldshleger R, Farman N, Blostein R, Karlish SJ. A functional interaction between CHIF and Na-K-ATPase: implication for regulation by FXYD proteins. Am J Physiol Renal Physiol 2002 283 : F607 15.
26. Beguin P, Crambert G, Guennoun S, Garty H, Horisberger JD, Geering K. CHIF, a member of the FXYD protein family, is a regulator of Na,K-ATPase distinct from the gamma-subunit. EMBO J 2001 20 : 3993 4002.
27. Mahmmoud YA, Cramb G, Maunsbach AB, Cutler CP, Meischke L, Cornelius F. Regulation of Na,K-ATPase by PLMS, the phospholemman-like protein from shark: molecular cloning, sequence, expression, cellular distribution, and functional effects of PLMS. J Biol Chem 2003 278 : 37427 38.
28. +-ATPase: role on ATPase activity and regulatory phosphorylation by PKA. Int J Biochem Cell Biol 2006 38 : 1901 13.
29. Crambert G, Beguin P, Uldry M, Monnet-Tschudi F, Horisberger JD, Garty H, Geering K. FXYD7, the first brain- and isoform-specific regulator of Na,K-ATPase: biosynthesis and function of its posttranslational modifications. Ann NY Acad Sci 2003 986 : 444 8.
30. Mahmmoud YA, Cornelius F. Protein kinase C phosphorylation of purified Na,K-ATPase: C-terminal phosphorylation sites at the alpha- and gamma-subunits close to the inner face of the plasma membrane. Biophys J 2002 82 : 1907 19.
31. Li C, Grosdidier A, Cramber G, Horisberger JD, Michielin O, Geering K. Structural and functional interaction sites between Na,K-ATPase and FXYD proteins. J Biol Chem 2004 279 : 38895 902.
32. Li C, Crambert G, Thuillard D, Roy S, Schaer D, Geering K. Role of the transmembrane domain of FXYD7 in structural and functional interactions with Na,K-ATPase. J Biol Chem 2005 280 : 42738 43.
33. Fuzesi M, Gottschalk KE, Lindzen M, Shainskaya A, Kuster B, Garty H, Karlish SJ. Covalent cross-links between the gamma subunit (FXYD2) and alpha and beta subunits of Na,K-ATPase: modeling the alpha-gamma interaction. J Biol Chem 2005 280 : 18291 301.
34. Fuzesi M, Goldshleger R, Garty H, Karlish SJ. Defining the nature and sites of interaction between FXYD proteins and Na,K-ATPase. Ann NY Acad Sci 2003 986 : 532 3.
35. +-ATPase: alpha/beta/FXYD subunit stoichiometry and cross-linking. J Biol Chem 2006 281 : 5947 55.
36. +-ATPase. Am J Physiol Renal Physiol 2007 293 : F1818 26.
37. 2+ ATPase. Proc Natl Acad Sci USA 2003 100 : 467 72.
38. Eckes B, Colucci-Guyon E, Smola H, Nodder S, Babinet C, Krieg T, Martin P. Impaired wound healing in embryonic and adult mice lacking vimentin. J Cell Sci 2000 113 (Pt 13) : 2455 62.
39. Gilles C, Polette M, Zahm JM, Tournier JM, Volders L, Foidart JM, Birembaut P. Vimentin contributes to human mammary epithelial cell migration. J Cell Sci 1999 112 (Pt 24) : 4615 25.