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Volumn 16, Issue 11, 2008, Pages 1789-1797

Inhibition of the IFN-β response in hepatocellular carcinoma by alternative spliced isoform of IFN regulatory factor-3

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; DOUBLE STRANDED RNA; INTERFERON; INTERFERON REGULATORY FACTOR 3; ISOPROTEIN; NEUTRALIZING ANTIBODY;

EID: 54949096928     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2008.201     Document Type: Article
Times cited : (45)

References (49)
  • 1
    • 33749420880 scopus 로고    scopus 로고
    • Novel concepts in hepatocellular carcinoma: From molecular research to clinical practice
    • Giannelli, G and Antonaci, S (2006). Novel concepts in hepatocellular carcinoma: From molecular research to clinical practice. J Clin Gastroentero1 40: 842-846.
    • (2006) J Clin Gastroentero1 , vol.40 , pp. 842-846
    • Giannelli, G.1    Antonaci, S.2
  • 2
    • 0033199168 scopus 로고    scopus 로고
    • p53 selective and nonselective replication Of an E1B-deleted adenovirus in hepatocellular carcinoma
    • Vollmer, CM, Ribas, A, Butterfield, LH, Dissette, VB, Andrews, KI, Eilber, FC et al. (1999). p53 selective and nonselective replication Of an E1B-deleted adenovirus in hepatocellular carcinoma. Cancer Res 59: 4369-4374.
    • (1999) Cancer Res , vol.59 , pp. 4369-4374
    • Vollmer, C.M.1    Ribas, A.2    Butterfield, L.H.3    Dissette, V.B.4    Andrews, K.I.5    Eilber, F.C.6
  • 3
    • 0033166096 scopus 로고    scopus 로고
    • A novel tumor-specific replication-restricted adenoviral vector for gene therapy of hepatocellular carcinoma
    • Hallenbeck, PL, Chang, YN, Hay, C, Golightly, D, Stewart, D, Lin, J et al. (1999). A novel tumor-specific replication-restricted adenoviral vector for gene therapy of hepatocellular carcinoma. Hum Gene Ther 10: 1721-1733.
    • (1999) Hum Gene Ther , vol.10 , pp. 1721-1733
    • Hallenbeck, P.L.1    Chang, Y.N.2    Hay, C.3    Golightly, D.4    Stewart, D.5    Lin, J.6
  • 5
    • 0032906912 scopus 로고    scopus 로고
    • Hepatoma-specific antitumor activity of an albumin enhancer/promoter regulated herpes simplex virus in vivo
    • Miyatake, SI, Tani, S, Feigenbaum, F, Sundaresan, P, Toda, H, Narumi, O et al. (1999). Hepatoma-specific antitumor activity of an albumin enhancer/promoter regulated herpes simplex virus in vivo. Gene Ther 6: 564-572.
    • (1999) Gene Ther , vol.6 , pp. 564-572
    • Miyatake, S.I.1    Tani, S.2    Feigenbaum, F.3    Sundaresan, P.4    Toda, H.5    Narumi, O.6
  • 6
    • 0034212631 scopus 로고    scopus 로고
    • Oncolysis of diffuse hepatocellular carcinoma by intravascular administration of a replication-competent, genetically engineered herpes virus
    • Pawlik, TM, Nakamura, H, Yoon, SS, Mullen, JT, Chandrasekhar, S, Chiocca, EA et al. (2000). Oncolysis of diffuse hepatocellular carcinoma by intravascular administration of a replication-competent, genetically engineered herpes virus. Cancer Res 60: 2790-2795.
    • (2000) Cancer Res , vol.60 , pp. 2790-2795
    • Pawlik, T.M.1    Nakamura, H.2    Yoon, S.S.3    Mullen, J.T.4    Chandrasekhar, S.5    Chiocca, E.A.6
  • 7
    • 0038756431 scopus 로고    scopus 로고
    • Oncolytic vesicular stomatitis virus for treatment of orthotopic hepatocellular carcinoma in immune-competent rats
    • Ebert, O, Shinozaki, K, Huang, TG, Savontaus, MJ, Garcia-Sastre, A and Woo, SL (2003). Oncolytic vesicular stomatitis virus for treatment of orthotopic hepatocellular carcinoma in immune-competent rats. Cancer Res 63: 3605-3611.
    • (2003) Cancer Res , vol.63 , pp. 3605-3611
    • Ebert, O.1    Shinozaki, K.2    Huang, T.G.3    Savontaus, M.J.4    Garcia-Sastre, A.5    Woo, S.L.6
  • 8
    • 33845731246 scopus 로고    scopus 로고
    • Phase I, open-label, dose-escalating study of a genetically engineered herpes simplex virus, NV1020, in subjects with metastatic colorectal carcinoma to the liver
    • Kemeny, N, Brown, K, Covey, A, Kim, T, Bhargava, A, Brody, L et al. (2006). Phase I, open-label, dose-escalating study of a genetically engineered herpes simplex virus, NV1020, in subjects with metastatic colorectal carcinoma to the liver. Hum Gene Ther 17: 1214-1224.
    • (2006) Hum Gene Ther , vol.17 , pp. 1214-1224
    • Kemeny, N.1    Brown, K.2    Covey, A.3    Kim, T.4    Bhargava, A.5    Brody, L.6
  • 9
    • 0000163167 scopus 로고    scopus 로고
    • Rhabdoviridae: The viruses and their replication
    • Knipe, DM and Howley, PM eds, 4th edn. Lippincott Williams & Wilkins: Philadelphia. pp
    • Rose, JK and Whitt, MA (2001). Rhabdoviridae: The viruses and their replication. In: Knipe, DM and Howley, PM (eds). Fields Virology, 4th edn. Lippincott Williams & Wilkins: Philadelphia. pp. 1221-1242.
    • (2001) Fields Virology , pp. 1221-1242
    • Rose, J.K.1    Whitt, M.A.2
  • 10
    • 0033929057 scopus 로고    scopus 로고
    • Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus
    • Stojdl, DF, Lichty, B, Knowles, S, Marius, R, Atkins, H, Sonenberg, N et al. (2000). Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus. Nat Med 6 821-825.
    • (2000) Nat Med , vol.6 , pp. 821-825
    • Stojdl, D.F.1    Lichty, B.2    Knowles, S.3    Marius, R.4    Atkins, H.5    Sonenberg, N.6
  • 11
    • 0033646858 scopus 로고    scopus 로고
    • Vesicular stomatitis virus (VSV) therapy of tumors
    • Balachandran, S and Barber, GN (2000). Vesicular stomatitis virus (VSV) therapy of tumors. IUBMB Life 50: 135-138.
    • (2000) IUBMB Life , vol.50 , pp. 135-138
    • Balachandran, S.1    Barber, G.N.2
  • 12
    • 2342637176 scopus 로고    scopus 로고
    • Syncytia induction enhances the oncolytic potential of vesicular stomatitis virus in virotherapy for cancer
    • Ebert, O, Shinozaki, K, Kournioti, C, Park, MS, Garcia-Sastre, A and Woo, SL (2004). Syncytia induction enhances the oncolytic potential of vesicular stomatitis virus in virotherapy for cancer. Cancer Res 64: 3265-3270.
    • (2004) Cancer Res , vol.64 , pp. 3265-3270
    • Ebert, O.1    Shinozaki, K.2    Kournioti, C.3    Park, M.S.4    Garcia-Sastre, A.5    Woo, S.L.6
  • 13
    • 1642443434 scopus 로고    scopus 로고
    • Oncolysis of multifocal hepatocellular carcinoma in the rat liver by hepatic artery infusion of vesicular stomatitis virus
    • Shinozaki, K, Ebert, O, Kournioti, C, Tai, YS and Woo, SL (2004). Oncolysis of multifocal hepatocellular carcinoma in the rat liver by hepatic artery infusion of vesicular stomatitis virus. Mol Ther 9: 368-376.
    • (2004) Mol Ther , vol.9 , pp. 368-376
    • Shinozaki, K.1    Ebert, O.2    Kournioti, C.3    Tai, Y.S.4    Woo, S.L.5
  • 14
    • 11244353292 scopus 로고    scopus 로고
    • Eradication of advanced hepatacellular carcinoma in rats via repeated hepatic arterial infusions of recombinant VSV
    • Shinozaki, K, Ebert, O and Woo, SL (2005). Eradication of advanced hepatacellular carcinoma in rats via repeated hepatic arterial infusions of recombinant VSV. Hepatology 41: 196-203.
    • (2005) Hepatology , vol.41 , pp. 196-203
    • Shinozaki, K.1    Ebert, O.2    Woo, S.L.3
  • 15
    • 0033761842 scopus 로고    scopus 로고
    • The matrix protein of vesicular stomatitis virus inhibits nucleocytoplasmic transport when it is in the nucleus and associated with nuclear pore complexes
    • Petersen, JM, Her, LS, Varvel, V, Lund, E and Dahlberg, JE (2000). The matrix protein of vesicular stomatitis virus inhibits nucleocytoplasmic transport when it is in the nucleus and associated with nuclear pore complexes. Mol Cell Biol 20: 8590-8601.
    • (2000) Mol Cell Biol , vol.20 , pp. 8590-8601
    • Petersen, J.M.1    Her, L.S.2    Varvel, V.3    Lund, E.4    Dahlberg, J.E.5
  • 16
    • 0033636997 scopus 로고    scopus 로고
    • Vesicular stomatitis virus matrix protein inhibits host cell gene expression by targeting the nucleoporin Nup98
    • von Kobbe, C, van Deursen, JM, Rodrigues, JP, Sitterlin, D, Bachi, A, Wu, X et al. (2000). Vesicular stomatitis virus matrix protein inhibits host cell gene expression by targeting the nucleoporin Nup98. Mol Cell 6: 1243-1252.
    • (2000) Mol Cell , vol.6 , pp. 1243-1252
    • von Kobbe, C.1    van Deursen, J.M.2    Rodrigues, J.P.3    Sitterlin, D.4    Bachi, A.5    Wu, X.6
  • 17
    • 0037384982 scopus 로고    scopus 로고
    • Ability of the matrix protein of vesicular stomatitis virus to suppress beta interferon gene expression is genetically correlated with the inhibition of host RNA and protein synthesis
    • Ahmed, M, McKenzie, MO, Puckett, S, Hojnacki, M, Poliquin, L and Lyles, DS (2003). Ability of the matrix protein of vesicular stomatitis virus to suppress beta interferon gene expression is genetically correlated with the inhibition of host RNA and protein synthesis. J Virol 77: 4646-4657.
    • (2003) J Virol , vol.77 , pp. 4646-4657
    • Ahmed, M.1    McKenzie, M.O.2    Puckett, S.3    Hojnacki, M.4    Poliquin, L.5    Lyles, D.S.6
  • 18
    • 10744223476 scopus 로고    scopus 로고
    • VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents
    • Stojdl, DF, Lichty, BD, tenOever, BR, Paterson, JM, Power, AT, Knowles, S et al. (2003). VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents. Cancer Cell 4: 263-275.
    • (2003) Cancer Cell , vol.4 , pp. 263-275
    • Stojdl, D.F.1    Lichty, B.D.2    tenOever, B.R.3    Paterson, J.M.4    Power, A.T.5    Knowles, S.6
  • 19
    • 0035005593 scopus 로고    scopus 로고
    • Different host-cell shutoff strategies related to the matrix protein lead to persistence of vesicular stomatitis virus mutants on fibroblast cells
    • Desforges, M, Charron, J, Berard, S, Beausoleil, S, Stojdl, DF, Despars, G et al. (2001). Different host-cell shutoff strategies related to the matrix protein lead to persistence of vesicular stomatitis virus mutants on fibroblast cells. Virus Res 76: 87-102.
    • (2001) Virus Res , vol.76 , pp. 87-102
    • Desforges, M.1    Charron, J.2    Berard, S.3    Beausoleil, S.4    Stojdl, D.F.5    Despars, G.6
  • 20
    • 33748455338 scopus 로고    scopus 로고
    • Type I interferons in host defense
    • Stetson, DB and Medzhitov, R (2006). Type I interferons in host defense. Immunity 25: 373-381.
    • (2006) Immunity , vol.25 , pp. 373-381
    • Stetson, D.B.1    Medzhitov, R.2
  • 21
    • 33750321707 scopus 로고    scopus 로고
    • Interferons, immunity and cancer immunoediting
    • Dunn, GP, Koebel, CM and Schreiber, RD (2006). Interferons, immunity and cancer immunoediting. Nat Rev Immunol 6: 836-848.
    • (2006) Nat Rev Immunol , vol.6 , pp. 836-848
    • Dunn, G.P.1    Koebel, C.M.2    Schreiber, R.D.3
  • 22
    • 0742322159 scopus 로고    scopus 로고
    • Interferons: Mechanisms of action and clinical applications
    • Parmar, S and Platanias, LC (2003). Interferons: Mechanisms of action and clinical applications. Curr Opin Oncol 15: 431-439.
    • (2003) Curr Opin Oncol , vol.15 , pp. 431-439
    • Parmar, S.1    Platanias, L.C.2
  • 23
    • 3242813113 scopus 로고    scopus 로고
    • The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
    • Yoneyama, M, Kikuchi, M, Natsukawa, T, Shinobu, N, Imaizumi, T, Miyagishi, M et al. (2004). The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 5: 730-737.
    • (2004) Nat Immunol , vol.5 , pp. 730-737
    • Yoneyama, M.1    Kikuchi, M.2    Natsukawa, T.3    Shinobu, N.4    Imaizumi, T.5    Miyagishi, M.6
  • 25
    • 0038363463 scopus 로고    scopus 로고
    • Triggering the interferon antiviral response through an IKK-related pathway
    • Sharma, S, tenOever, BR, Grandvaux, N, Zhou, GP, Lin, R and Hiscom J (2003). Triggering the interferon antiviral response through an IKK-related pathway. Science 300; 1148-1151.
    • (2003) Science , vol.300 , pp. 1148-1151
    • Sharma, S.1    tenOever, B.R.2    Grandvaux, N.3    Zhou, G.P.4    Lin, R.5    Hiscom, J.6
  • 26
    • 0038660668 scopus 로고    scopus 로고
    • Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA
    • Servant, MJ, Grandvaux, N, tenOever, BR, Duguay, D, Lin, R and Hiscott, J (2003). Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA. J. Biol Chem 278: 9441-9447.
    • (2003) J. Biol Chem , vol.278 , pp. 9441-9447
    • Servant, M.J.1    Grandvaux, N.2    tenOever, B.R.3    Duguay, D.4    Lin, R.5    Hiscott, J.6
  • 27
    • 0034669027 scopus 로고    scopus 로고
    • Dual utilization of an acceptor/donor splice site governs the alternative splicing of the IRF-3 gene
    • Karpova, AY, Howley, PM and Ronco, LV (2000). Dual utilization of an acceptor/donor splice site governs the alternative splicing of the IRF-3 gene. Genes Dev 14: 2813-2818.
    • (2000) Genes Dev , vol.14 , pp. 2813-2818
    • Karpova, A.Y.1    Howley, P.M.2    Ronco, L.V.3
  • 28
    • 0034972164 scopus 로고    scopus 로고
    • Functional characterization of interferon regulatory factor 3a (IRF-3a), an alternative splice isoform of IRF-3
    • Karpova, AY, Ronco, LV and Howley, PM (2001). Functional characterization of interferon regulatory factor 3a (IRF-3a), an alternative splice isoform of IRF-3. Mol Cell Biol 21: 4169-4176.
    • (2001) Mol Cell Biol , vol.21 , pp. 4169-4176
    • Karpova, A.Y.1    Ronco, L.V.2    Howley, P.M.3
  • 29
    • 1542723466 scopus 로고    scopus 로고
    • Toll-like receptor 3-mediated activation of NF-κB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-β
    • Jiang, Z, Mak, TW, Sen, G and Li, X (2004). Toll-like receptor 3-mediated activation of NF-κB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-β. Proc Natl Acad Sci USA 101: 3533-3538.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3533-3538
    • Jiang, Z.1    Mak, T.W.2    Sen, G.3    Li, X.4
  • 30
    • 33947206046 scopus 로고    scopus 로고
    • Cutting Edge: Influenza A virus activates TLR3-dependent inflammatory and RIG-I-dependent antiviral responses in human lung epithelial cells
    • Le Goffic, R, Pothlichet, J, Vitour, D, Fujita, T, Meurs, E, Chignard, M et al. (2007). Cutting Edge: Influenza A virus activates TLR3-dependent inflammatory and RIG-I-dependent antiviral responses in human lung epithelial cells. J Immunol 178: 3368-3372.
    • (2007) J Immunol , vol.178 , pp. 3368-3372
    • Le Goffic, R.1    Pothlichet, J.2    Vitour, D.3    Fujita, T.4    Meurs, E.5    Chignard, M.6
  • 31
    • 38449099395 scopus 로고    scopus 로고
    • Viral regulation and evasion of the host response
    • Loo, YM and Gale, M Jr. (2007). Viral regulation and evasion of the host response. Curr Top Microbiol Immunol 316: 295-313.
    • (2007) Curr Top Microbiol Immunol , vol.316 , pp. 295-313
    • Loo, Y.M.1    Gale Jr., M.2
  • 32
    • 20444442721 scopus 로고    scopus 로고
    • Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-β production in hepatocytes
    • Li, K, Chen, Z, Kato, N, Gale, M Jr. and Lemon, SM (2005). Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-β production in hepatocytes. J Biol Chem 280: 16739-16747.
    • (2005) J Biol Chem , vol.280 , pp. 16739-16747
    • Li, K.1    Chen, Z.2    Kato, N.3    Gale Jr., M.4    Lemon, S.M.5
  • 33
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
    • Alexopoulou, L, Holt, AC, Medzhitov, R and Flavell, RA (2001). Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413: 732-738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 37
    • 29144462494 scopus 로고    scopus 로고
    • Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity
    • Li, XD, Sun, L, Seth, RB, Pineda, G and Chen, ZJ (2005). Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity. Proc Natl Acad Sci USA 102: 17717-17722.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 17717-17722
    • Li, X.D.1    Sun, L.2    Seth, R.B.3    Pineda, G.4    Chen, Z.J.5
  • 38
    • 36148985702 scopus 로고    scopus 로고
    • Peripheral, but not central nervous system, type I interferon expression in mice in response to intranasal vesicular stomatitis virus infection
    • Trottier, MD, Lyles, DS and Reiss, CS (2007). Peripheral, but not central nervous system, type I interferon expression in mice in response to intranasal vesicular stomatitis virus infection. J Neurovirol 13: 433-445.
    • (2007) J Neurovirol , vol.13 , pp. 433-445
    • Trottier, M.D.1    Lyles, D.S.2    Reiss, C.S.3
  • 39
    • 34547097764 scopus 로고    scopus 로고
    • The RAS/Raf1/MEK/ERK signaling pathway facilitates VSV-mediated oncolysis: Implication for the defective interferon response in cancer cells
    • Noser, JA, Mael, AA, Sakuma, R, Ohmine, S, Marcato, P, Wk Lee, P et al. (2007). The RAS/Raf1/MEK/ERK signaling pathway facilitates VSV-mediated oncolysis: Implication for the defective interferon response in cancer cells. Mol Ther 15: 1531-1536.
    • (2007) Mol Ther , vol.15 , pp. 1531-1536
    • Noser, J.A.1    Mael, A.A.2    Sakuma, R.3    Ohmine, S.4    Marcato, P.5    Wk Lee, P.6
  • 40
    • 0242574745 scopus 로고    scopus 로고
    • Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation
    • Qin, BY, Liu, C, Lam, SS, Srinath, H, Delston, R, Correia, JJ et al. (2003). Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation. Nat Struct Biol 10: 913-921.
    • (2003) Nat Struct Biol , vol.10 , pp. 913-921
    • Qin, B.Y.1    Liu, C.2    Lam, S.S.3    Srinath, H.4    Delston, R.5    Correia, J.J.6
  • 43
    • 33746339222 scopus 로고    scopus 로고
    • Alternative splicing variants of IRF-1 lacking exons 7, 8, and 9 in cervical cancer
    • Lee, EJ, Jo, M, Park, J, Zhang, W and Lee, JH (2006). Alternative splicing variants of IRF-1 lacking exons 7, 8, and 9 in cervical cancer. Biochem Biophys Res Commun 347: 882-888.
    • (2006) Biochem Biophys Res Commun , vol.347 , pp. 882-888
    • Lee, E.J.1    Jo, M.2    Park, J.3    Zhang, W.4    Lee, J.H.5
  • 44
    • 0035909521 scopus 로고    scopus 로고
    • HBV integrants of hepatocellular carcinoma cell lines contain an active enhancer
    • Shamay, M, Agami, R and Shaul, Y (2001). HBV integrants of hepatocellular carcinoma cell lines contain an active enhancer. Oncogene 20: 6811-6819.
    • (2001) Oncogene , vol.20 , pp. 6811-6819
    • Shamay, M.1    Agami, R.2    Shaul, Y.3
  • 45
    • 36348936640 scopus 로고    scopus 로고
    • Hepatitis C virus escape from the interferon regulatory factor 3 pathway by a passive and active evasion strategy
    • Binder, M, Kochs, G, Bartenschlager, R and Lohmann, V (2007). Hepatitis C virus escape from the interferon regulatory factor 3 pathway by a passive and active evasion strategy. Hepatology 46: 1365-1374.
    • (2007) Hepatology , vol.46 , pp. 1365-1374
    • Binder, M.1    Kochs, G.2    Bartenschlager, R.3    Lohmann, V.4
  • 46
    • 0037228023 scopus 로고    scopus 로고
    • Antiviral effect and virus-host interactions in response to alpha interferon, gamma interferon, Poly(I)-Poly(C), tumor necrosis factor alpha, and Ribavirin in hepatitis C virus subgenomic replicons
    • Lanfor, RE, Guerra, B, Lee, H, Averett, DR, Pfeiffer, B, Chavez, D et al. (2003). Antiviral effect and virus-host interactions in response to alpha interferon, gamma interferon, Poly(I)-Poly(C), tumor necrosis factor alpha, and Ribavirin in hepatitis C virus subgenomic replicons. J Virol 77: 1092-1104.
    • (2003) J Virol , vol.77 , pp. 1092-1104
    • Lanfor, R.E.1    Guerra, B.2    Lee, H.3    Averett, D.R.4    Pfeiffer, B.5    Chavez, D.6
  • 47
    • 34547796858 scopus 로고    scopus 로고
    • Limited suppression of the interferon-β production by hepatitis C virus serine protease in cultured human hepatocytes
    • Dansako, H, Ikeda, M and Kato, N (2007). Limited suppression of the interferon-β production by hepatitis C virus serine protease in cultured human hepatocytes. FEBS J 274: 4161-4176.
    • (2007) FEBS J , vol.274 , pp. 4161-4176
    • Dansako, H.1    Ikeda, M.2    Kato, N.3
  • 48
    • 0345547477 scopus 로고    scopus 로고
    • Charitable state-controlled foundation human tissue and cell research: Ethic and legal aspects in the supply of surgically removed human tissue for research in the academic and commercial sector in Germany
    • Thasler, WE, Weiss, TS, Schillhorn, K, Stoll, PT, Irrgang, B and Jauch, KW (2003). Charitable state-controlled foundation human tissue and cell research: Ethic and legal aspects in the supply of surgically removed human tissue for research in the academic and commercial sector in Germany. Cell Tissue Bank 4: 49-56.
    • (2003) Cell Tissue Bank , vol.4 , pp. 49-56
    • Thasler, W.E.1    Weiss, T.S.2    Schillhorn, K.3    Stoll, P.T.4    Irrgang, B.5    Jauch, K.W.6
  • 49
    • 15744371199 scopus 로고    scopus 로고
    • Systemic therapy of experimental breast cancer metastases by mutant vesicular stomatitis virus in immune-competent mice
    • Ebert, O, Harbaran, S, Shinozaki, K and Woo, SL (2005). Systemic therapy of experimental breast cancer metastases by mutant vesicular stomatitis virus in immune-competent mice. Cancer Gene Ther 12: 350-358.
    • (2005) Cancer Gene Ther , vol.12 , pp. 350-358
    • Ebert, O.1    Harbaran, S.2    Shinozaki, K.3    Woo, S.L.4


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