Fetal nasal bone status in Chinese women undergoing first-trimester screening for trisomy 21

American Journal of Obstetrics and Gynecology

Volumn 199, Issue 5, 2008, Pages 521.e1-521.e5

  Leung, Tak Yeung ^a   Sahota, Daljit ^a   Chan, Lin Wai ^a   Law, Lai Wa ^a   Fung, Tak Yuen ^a   Lau, Tze Kin ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Chinese; nasal bone; nuchal translucency; screening; trisomy 21

Indexed keywords

ADULT; ARTICLE; CAUCASIAN; CHINESE; CONTROLLED STUDY; CROWN RUMP LENGTH; FEMALE; FETUS; FETUS KARYOTYPING; FIRST TRIMESTER PREGNANCY; GENETIC RISK; GESTATION PERIOD; HUMAN; MAJOR CLINICAL STUDY; MATERNAL AGE; NASAL BONE; NUCHAL TRANSLUCENCY MEASUREMENT; PRENATAL SCREENING; PRIORITY JOURNAL; TRISOMY 21;

EID: 54849406143     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2008.04.045     Document Type: Article

References (15)

1. Nicolaides K.H. First-trimester screening for chromosomal abnormalities. Semin Perinatol 29 (2005) 190-194
2. Guis F., Ville Y., Vincent Y., Doumerc S., Pons J.C., and Frydman R. Ultrasound evaluation of the length of the fetal nasal bones throughout gestation. Ultrasound Obstet Gynecol 5 (1995) 304-307
3. Cicero S., Curcio P., Papageorghiou A., Sonek J., and Nicolaides K. Absence of nasal bone in fetuses with trisomy 21 at 11-14 weeks of gestation: An observational study. Lancet 358 (2001) 1665-1667
4. Cicero S., Rembouskos G., Vandecruys H., Hogg M., and Nicolaides K.H. Likelihood ratio for trisomy 21 in fetuses with absent nasal bone at the 11-14-week scan. Ultrasound Obstet Gynecol 23 (2004) 218-223
5. Sonek J.D., and Nicolaides K.H. Prenatal ultrasonographic diagnosis of nasal bone abnormalities in three fetuses with Down syndrome. Am J Obstet Gynecol 186 (2002) 139-141
6. Otaño L., Aiello H., Igarzábal L., Matayoshi T., and Gadow E.C. Association between first trimester absence of fetal nasal bone on ultrasound and Down syndrome. Prenat Diagn 22 (2002) 930-932
7. Wong S.F., Choi H., and Ho L.C. Nasal bone hypoplasia: Is it a common finding amongst chromosomally normal fetuses of southern Chinese women?. Gynecol Obstet Invest 56 (2003) 99-101
8. Moon M.H., Cho J.Y., Lee Y.M., et al. First-trimester screening for Down syndrome; the role of nasal bone assessment in the Korean population. Prenat Diagn 27 (2007) 830-834
9. Cicero S., Avgidou K., Rembouskos G., Kagan K.O., and Nicolaides K.H. Nasal bone in first-trimester screening for trisomy 21. Am J Obstet Gynecol 195 (2006) 109-114
10. Cicero S., Dezerega V., Andrade E., Scheier M., and Nicolaides K.H. Learning curve for sonographic examination of the fetal nasal bone at 11-14 weeks. Ultrasound Obstet Gynecol 22 (2003) 135-137
11. Prefumo F., Sairam S., Bhide A., Penna L., Hollis B., and Thilaganathan B. Maternal ethnic origin and fetal nasal bones at 11-14 weeks of gestation. BJOG 111 (2004) 109-112
12. Prefumo F., Sairam S., Bhide A., and Thilaganathan B. First-trimester nuchal translucency, nasal bones, and trisomy 21 in selected and unselected populations. Am J Obstet Gynecol 194 (2006) 828-833
13. Thilaganathan B., Khare M., Williams B., and Wathen N.C. Influence of ethnic origin on nuchal translucency screening for Down's syndrome. Ultrasound Obstet Gynecol 12 (1998) 112-114
14. Nicolaides K.H., Snijders R.J., and Cuckle H.S. Correct estimation of parameters for ultrasound nuchal translucency screening. Prenat Diagn 18 (1998) 519-523
15. Chen M., Lam Y.H., Tang M.H., et al. The effect of ethnic origin on nuchal translucency at 10-14 weeks of gestation. Prenat Diagn 22 (2002) 576-578