Neural correlates of the clock drawing test performance in Alzheimer's disease: A FDG-PET study

Dementia and Geriatric Cognitive Disorders

Volumn 26, Issue 4, 2008, Pages 306-313

  Lee, Dong Young ^a,d   Seo, Eun Hyun ^d   Choo, Il Han ^a   Kim, Shin Gyeom ^e   Lee, Jae Sung ^b   Lee, Dong Su ^b   Jhoo, Jin Hyeong ^f   Kim, Ki Woong ^g   Youn, Jong Choul ^h   Woo, Jong Inn ^a,b,c,d  

^a Seoul National University   (South Korea)

^b Seoul National University Hospital   (South Korea)

^c National Medical Center   (South Korea)

^d Seoul National University   (South Korea)

^e Soonchunhyang University College of Medicine   (South Korea)

^f Kangwon National University   (South Korea)

^g Seoul National University Bundang Hospital   (South Korea)

^h Kyunggi Provincial Hospital for Elderly   (South Korea)

Author keywords

Alzheimer's disease; Clock drawing test; Neural correlate; PET

Indexed keywords

FLUORODEOXYGLUCOSE F 18; GLUCOSE;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CINGULATE GYRUS; CLOCK DRAWING TEST; CONTROLLED STUDY; FEMALE; GLUCOSE BRAIN LEVEL; GLUCOSE METABOLISM; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROPSYCHOLOGICAL TEST; PARIETAL LOBE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RIGHT HEMISPHERE; SCORING SYSTEM; SCREENING TEST; TASK PERFORMANCE;

AGED; ALZHEIMER DISEASE; BRAIN CHEMISTRY; BRAIN MAPPING; DATA INTERPRETATION, STATISTICAL; FEMALE; FLUORODEOXYGLUCOSE F18; FUNCTIONAL LATERALITY; GLUCOSE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; NEUROPSYCHOLOGICAL TESTS; PARIETAL LOBE; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS;

EID: 54749128269     PISSN: 14208008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000161055     Document Type: Article

References (31)

1. Rouleau I, Salmon DP, Butters N: Longitudinal analysis of clock drawing in Alzheimer's disease patients. Brain Cogn 1996;31:17-34.
2. Tuokko H, Hadjistavropoulos T, Miller JA, Beattie BL: The clock test: a sensitive measure to differentiate normal elderly from those with Alzheimer disease. J Am Geriatr Soc 1992;40:579-584.
3. Mendez MF, Ala T, Underwood KL: Development of scoring criteria for the clock drawing task in Alzheimer's disease. J Am Geriatr Soc 1992;40:1095-1099.
4. Sunderland T, Hill JL, Mellow AM, Lawlor BA, Gundersheimer J, Newhouse PA, Grafman JH: Clock drawing in Alzheimer's disease. A novel measure of dementia severity. J Am Geriatr Soc 1989;37:725-729.
5. Freedman M, Leach L, Kaplan E, Winocur G, Shulman K, Delis DC: Clock Drawing: A Neuropsychological Analysis, ed 3. New York, Oxford University Press, 1994.
6. Nagahama Y, Okina T, Suzuki N, Nabatame H, Matsuda M: Neural correlates of impaired performance on the clock drawing test in Alzheimer's disease. Dement Geriatr Cogn Disord 2005;19:390-396.
7. Libon DJ, Malamut BL, Swenson R, Sands LP, Cloud BS: Further analyses of clock drawings among demented and nondemented older subjects. Arch Clin Neuropsychol 1996;11:193-205.
8. Rouleau I, Salmon DP, Butters N, Kennedy C, McGuire K: Quantitative and qualitative analyses of clock drawings in Alzheimer's disease and Huntington's disease. Brain Cogn 1992;18:70-87.
9. Ueda H, Kitabayashi Y, Narumoto J, Nakamura K, Kita H, Kishikawa Y, Fukui K: Relationship between clock drawing test performance and regional cerebral blood flow in Alzheimer's disease: a single photon emission computed tomography study. Psychiatry Clin Neurosci 2002;56:25-29.
10. Cahn-Weiner DA, Sullivan EV, Shear PK, Fama R, Lim KO, Yesavage JA, Tinklenberg JR, Pfefferbaum A: Brain structural and cognitive correlates of clock drawing performance in Alzheimer's disease. J Int Neuropsychol Soc 1999;5:502-509.
11. Lezac MD, Howieson DB, Loring DW: Neuropsychological Assessment, ed 4. New York, Oxford University Press, 2004.
12. Braak H, Braak E: Neuropathological staging of Alzheimer-related changes. Acta Neuropathol 1991;82:239-259.
13. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, ed 4. Washington, American Psychiatric Association, 1994.
14. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM: Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
15. Lee JH, Lee KU, Lee DY, Kim KW, Jhoo JH, Kim JH, Lee KH, Kim SY, Han SH, Woo JI: Development of the Korean version of the Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet (CERAD-K): clinical and neuropsychological assessment battery. J Gerontol Psychol Sci 2002;57:47-53.
16. Morris JC, Heyman A, Mohs RC, Hughes JP, van Belle G, Fillenbaum G, Mellits ED, Clark C: The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease. Neurology 1989;39:1159-1165.
17. Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL: A new clinical scale for the staging of dementia. Br J Psychiatry 1982;140:566-572.
18. Todd ME, Dammers PM, Adams SG Jr, Todd HM, Morrison M: An examination of a proposed scoring procedure for the clock drawing test: reliability and predictive validity of the clock scoring system (CSS). Am J Alzheimer's Dis 1995;10:22-26.
19. Lee DY, Lee KU, Lee JH, Kim KW, Jhoo JH, Kim SY, Yoon JC, Woo SI, Ha J, Woo JI: A normative study of the CERAD neuropsychological assessment battery in the Korean elderly. J Int Neuropsychol Soc 2004;10:72-81.
20. Friston KJ, Holmes AP, Worsley KJ, Poline JP, Frith CD, Frackowiak RSJ: Statistical parametric maps in functional imaging: a general linear approach. Hum Brain Mapp 1995;2:189-210.
21. Friston KJ, Ashburner J, Frith CD, Poline JB, Heather JD, Frackowiak RSJ: Spatial registration and normalization of images. Hum Brain Mapp 1995;2:165-169.
22. Minoshima S, Frey KA, Foster NL, Kuhl DE: Preserved pontine glucose metabolism in Alzheimer disease: a reference region for functional brain image (PET) analysis. J Comput Assist Tomogr 1995;19:541-547.
23. Talairach J, Tournoux P: Co-Planar Stereotaxic Altlas of the Human Brain. New York, Thieme, 1988.
24. Saumier D, Chertkow H: Semantic memory. Curr Neurol Neurosci Rep 2002;2:516-522.
25. Moscovitch M, Rosenbaum RS, Gilboa A, Addis DR, Westmacott R, Grady C, McAndrews MP, Levine B, Black S, Winocur G, Nadel L: Functional neuroanatomy of remote episodic, semantic and spatial memory: a unified account based on multiple trace theory. J Anat 2005;207:35-66.
26. Bohbot VD, Allen JJB, Nadel L: Memory deficits characterized by patterns of lesions to the hippocampus and parahippocampal cortex. Ann NY Acad Sci 2000;911:355-368.
27. Johnsrude IS, Owen AM, Crane J, Milner B, Evans AC: A cognitive activation study of memory for spatial relationships. Neuropsycholgia 1999;37:829-841.
28. Bohbot VD, Kalina M, Stepankova K, Spackova N, Petrides M, Nadel L: Spatial memory deficits in patients with lesions to the right hippocampus and to the right parahippocampal cortex. Neuropsychologia 1998;36:1217-1238.
29. Owen AM, Milner B, Petrides M, Evans AC: Memory for object features versus memory for object location: a positron-emission tomography study of encoding and retrieval processes. Proc Natl Acad Sci USA 1996;93:9212-9217.
30. Ungerleider LG, Haxby JV: 'What' and 'where' in the human brain. Curr Opin Neurobiol 1994;4:157-165.
31. Förstl H, Burns A, Levy R, Cairns NL: Neuropathologial basis for drawing disability (constructional apraxia) in Alzheimer's disease. Psychol Med 1993;23:623-629.