Cytotoxic T lymphocyte associated antigen-4 exon 1 A/G polymorphism in Iranian patients with multiple sclerosis

European Journal of Neurology

Volumn 15, Issue 8, 2008, Pages 862-864

  Haghighi, A Borhani ^a,d   Ghahramani, S ^a   Azarpira, N ^b   Pourjafar, M ^c   Nikseresht, A R ^a  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c Beheshti Hospital   (Iran)

^d SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cytotoxic T lymphocyte antigen 4; Multiple sclerosis; Polymorphism

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; CYTOTOXIC T-LYMPHOCYTE ANTIGEN 4; LEUKOCYTE ANTIGEN;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; EXON; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; IRAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; GENETIC PREDISPOSITION; GENETICS; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ANTIGENS, CD; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IRAN; MALE; MULTIPLE SCLEROSIS; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 54549122393     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2008.02153.x     Document Type: Article

References (12)

1. Ueda H, Howson JM, Esposito L, et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 2003; 423: 506-511.
2. Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Annals of Neurology 1983; 13: 227-231.
3. Heward J, Gordon C, Allahabadia A, Barnett AH, Franklyn JA, Gough SC. The A-G polymorphism in exon 1 of the CTLA-4 gene is not associated with systemic lupus erythematosus. Annals of the Rheumatic Diseases 1999; 58: 193-195.
4. Ligers A, Xu C, Saarinen S, Hillert J, Olerup O. The CTLA-4 gene is associated with multiple sclerosis. Journal of Neuroimmunology 1999; 97: 182-190.
5. Fukazawa T, Yanagawa T, Kikuchi S, et al. CTLA-4 gene polymorphism may modulate disease in Japanese multiple sclerosis patients. Journal of the Neurological Sciences 1999; 171: 49-55.
6. Harbo HF, Celius EG, Vartdal F, Spurkland A. CTLA4 promoter and exon 1 dimorphisms in multiple sclerosis. Tissue Antigens 1999; 53: 106-110.
7. Masterman T, Ligers A, Zhang Z, et al. CTLA4 dimorphisms and the multiple sclerosis phenotype. Journal of Neuroimmunology 2002; 131: 208-212.
8. Van Veen T, Crusius JB, van Winsen L, et al. CTLA-4 and CD28 gene polymorphisms in susceptibility, clinical course and progression of multiple sclerosis. Journal of Neuroimmunology 2003; 140: 188-193.
9. Bocko D, Bilinska M, Dobosz T, et al. Lack of association between an exon 1 CTLA-4 gene polymorphism A(49)G and multiple sclerosis in a Polish population of the Lower Silesia region. Archivum Immunologiae et Therapiae Experimentalis (Warsz) 2003; 51: 201-205.
10. Teutsch SM, Booth DR, Bennetts BH, Heard RN, Stewart GJ. Association of common T cell activation gene polymorphisms with multiple sclerosis in Australian patients. Journal of Neuroimmunology 2004; 148: 218-230.
11. Greve B, Simonenko R, Illes Z, et al. Multiple sclerosis and the CTLA4 autoimmunity polymorphism CT60: no association in patients from Germany, Hungary and Poland. Multiple Sclerosis 2008; 14: 153-158.
12. Kantarci OH, Hebrink DD, Achenbach SJ, et al. CTLA4 is associated with susceptibility to multiple sclerosis. Journal of Neuroimmunology 2003; 134: 133-141.