A new diastereoselective multicomponent, one-pot strategy for the synthesis of 3-substituted isoindolinones via efficient C-C bond formation

Tetrahedron

Volumn 64, Issue 49, 2008, Pages 11115-11123

  Wan, Jie Ping ^a   Zhou, Jing ^a   Mao, Hui ^a   Pan, Yuan Jiang ^a   Wu, An Xin ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b CENTRAL CHINA NORMAL UNIVERSITY   (China)

Author keywords

3 Substituted isoindolinones; C C bond formation; Multicomponent; One pot

Indexed keywords

1 OXO N PHENYL 3 [(3 PHENYLUREIDO) (4 CHLOROPHENYL)METHYL]ISOINDOLINE 2 CARBOXAMIDE; 1 OXO N PHENYL 3 [(3 PHENYLUREIDO) (4 TOLYL)METHYL]ISOINDOLINE 2 CARBOXAMIDE; 1 OXO N PHENYL 3 [(3 PHENYLUREIDO) [4 (TRIFLUOROMETHYL)PHENYL]METHYL]ISOINDOLINE 2 CARBOXAMIDE; 1 OXO N PHENYL 3 [(4 FLUOROPHENYL) (3 PHENYLUREIDO)METHYL]ISOINDOLINE 2 CARBOXAMIDE; 1 OXO N PHENYL 3 [PHENYL (3 PHENYLUREIDO)METHYL]ISOINDOLINE 2 CARBOXAMIDE; INDOLE DERIVATIVE; ISOINDOLINONE DERIVATIVE; N ETHYL 1 [(3 ETHYLUREIDO) (2 FLUOROPHENYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N ETHYL 1 [(3 ETHYLUREIDO) (3 METHOXYPHENYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N ETHYL 1 [(3 ETHYLUREIDO) (3 NITROPHENYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N ETHYL 1 [(3 ETHYLUREIDO) (4 BROMOPHENYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N ETHYL 1 [(3 ETHYLUREIDO) (4 CHLOROPHENYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N ETHYL 1 [(3 ETHYLUREIDO) (4 FLUOROPHENYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N ETHYL 1 [(3 ETHYLUREIDO) (4 HYDROXYPHENYL)METHYL] 3 OXOISOINDOLINONE 2 CARBOXAMIDE; N ETHYL 1 [(3 ETHYLUREIDO) (4 METHOXYPHENYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N ETHYL 1 [(3 ETHYLUREIDO) (4 TOLYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N ETHYL 1 [(3 ETHYLUREIDO)(NAPHTHALEN 1 YL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N ETHYL 1 [(3 ETHYLUREIDO)(PHENYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N ETHYL 1 [[(3 ETHYLUREIDO) 4 (DIMETHYLAMINO)PHENYL]METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N ETHYL 1 [[(3 ETHYLUREIDO) [4(TRIFLUOROMETHYL)PHENYL]METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N METHYL 1 [(3 METHYLUREIDO) (2 CHLOROPHENYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N METHYL 1 [(3 METHYLUREIDO) (3 NITROPHENYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N METHYL 1 [(3 METHYLUREIDO) (4 BROMOPHENYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N METHYL 1 [(3 METHYLUREIDO) (4 FLUOROPHENYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N METHYL 1 [(3 METHYLUREIDO) (4 METHOXYPHENYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N METHYL 1 [(3 METHYLUREIDO) (4 TOLYL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N METHYL 1 [(3 METHYLUREIDO) [4 (TRIFLUOROMETHYL)PHENYL]METHYL] 3 OXOISOINDOLINE 3 CARBOXAMIDE; N METHYL 1 [(3 METHYLUREIDO)(NAPHTHALEN 1 YL)METHYL] 3 OXOISOINDOLINE 2 CARBOXAMIDE; N METHYL 1 [(3 METHYLUREIDO)(PHENYL)METHYL] 3 OXOISOINDOLINE 3 CARBOXAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; CHEMICAL REACTION; DIASTEREOISOMER; DRUG STRUCTURE; DRUG SYNTHESIS; ONE POT SYNTHESIS; PRIORITY JOURNAL; STEREOCHEMISTRY;

EID: 54549113026     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.09.092     Document Type: Article

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