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Volumn 78, Issue 4, 2008, Pages

Effects of the chemomechanical stepping cycle on the traffic of molecular motors

Author keywords

[No Author keywords available]

Indexed keywords

LINEAR MOTORS;

EID: 54549110285     PISSN: 15393755     EISSN: 15502376     Source Type: Journal    
DOI: 10.1103/PhysRevE.78.041909     Document Type: Article
Times cited : (49)

References (33)
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    • In general, if motors may unbind in a conformation different from the one they had immediately after binding, one step per run corresponds to an incomplete chemical cycle. This incomplete cycle leads to a correction of the probabilities Pi compared to the case where the chemical cycle is completed in each step. This correction is thus of order 1/(number of steps per run) and has a very small effect for processive motors.
    • In general, if motors may unbind in a conformation different from the one they had immediately after binding, one step per run corresponds to an incomplete chemical cycle. This incomplete cycle leads to a correction of the probabilities Pi compared to the case where the chemical cycle is completed in each step. This correction is thus of order 1/(number of steps per run) and has a very small effect for processive motors.
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    • The small nonzero value of 2 in has been introduced to avoid an artificial absorbing state, given by a filament fully occupied by motors in state 2, from which the system cannot escape within the simplest models if 2 =0. An alternative would be to introduce a reverse transition from state 2 to state 1 at the same position.
    • The small nonzero value of 2 in has been introduced to avoid an artificial absorbing state, given by a filament fully occupied by motors in state 2, from which the system cannot escape within the simplest models if 2 =0. An alternative would be to introduce a reverse transition from state 2 to state 1 at the same position.
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    • The peculiar shape of the curve reflects the change in the dominant unbinding pathway towards unbinding from state 2 at high unbound motor concentrations.
    • The peculiar shape of the curve reflects the change in the dominant unbinding pathway towards unbinding from state 2 at high unbound motor concentrations.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.