Lack of correlation between antibody titers to fibrinogen-binding protein of Streptococcus equi and persistent carriers of strangles

Journal of Veterinary Diagnostic Investigation

Volumn 20, Issue 4, 2008, Pages 457-462

  Davidson, Ann ^a,b   Traub Dargatz, Josie L ^a   Magnuson, Roberta ^b   Hill, Ashley ^b   Irwin, Vivienne ^e   Newton, Richard ^c   Waller, Andrew ^c   Smith, Kenneth ^d   Callan, Robert J ^a   Meehan, Mary ^g   Owen, Peter ^f   Salman, Mo ^b  

^a Department of Clinical Sciences ^*

^b Veterinary Dentistry and Oral Surgery   (United States)

^c ANIMAL HEALTH TRUST   (United Kingdom)

^d ROYAL VETERINARY COLLEGE   (United Kingdom)

^e QUEENSLAND HEALTH   (Australia)

^f CHILDREN S UNIVERSITY HOSPITAL   (Ireland)

^g TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Enzyme linked immunosorbent assay; Persistent carrier; Serologic response; Strangles

Indexed keywords

EQUIDAE; STREPTOCOCCUS EQUI;

BACTERIAL PROTEIN; BACTERIUM ANTIBODY; CARRIER PROTEIN; FIBRINOGEN BINDING PROTEIN, STREPTOCOCCUS EQUI; FIBRINOGEN-BINDING PROTEIN, STREPTOCOCCUS EQUI;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDEMIC; HETEROZYGOTE; HORSE; HORSE DISEASE; IMMUNOLOGY; MICROBIOLOGY; REPRODUCIBILITY; STREPTOCOCCUS EQUI; STREPTOCOCCUS INFECTION;

ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL PROTEINS; CARRIER PROTEINS; CARRIER STATE; DISEASE OUTBREAKS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HORSE DISEASES; HORSES; REPRODUCIBILITY OF RESULTS; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS EQUI;

EID: 54549089901     PISSN: 10406387     EISSN: None     Source Type: Journal    
DOI: 10.1177/104063870802000407     Document Type: Article

References (16)

1. Chanter N, Newton JR, Wood JL, et al.: 1998, Detection of strangles carrier [letter]. Vet Rec 142:496.
2. George JL, Reif JS, Shideler RK, et al.: 1983, Identification of carriers of Streptococcus equi in a naturally infected herd. J Am Vet Med Assoc 183:1394-1398.
3. Harrington DJ, Sutcliffe IC, Chanter N: 2002, The molecular basis of Streptococcus equi infection and disease. Microbes Infect 4:501-510.
4. Kelly C, Bugg M, Robinson C, et al.: 2006, Sequence variation of the SeM gene of Streptococcus equi allows discrimination of the source of strangles outbreaks. J Clin Microbiol 44:480-486.
5. Meehan M, Lynagh Y, Woods C, Owen P: 2001, The fibrinogen-binding protein (FgBP) of Streptococcus equi subsp. equi additionally binds IgG and contributes to virulence in a mouse model. Microbiology 147:3311-3322.
6. Meehan M, Nowlan P, Owen P: 1998. Affinity purification and characterization of a fibrinogen-binding protein complex which protects mice against lethal challenge with Streptococcus equi subsp. equi. Microbiology 144:993-1003.
7. Newton JR, Verheyen K, Talbot NC, et al.: 2000. Control of strangles outbreaks by isolation of guttural pouch carriers identified using PCR and culture of Streptococcus equi. Equine Vet J 32:515-526.
8. Sheoran AS, Sponseller BT, Holmes MA, Timoney JF: 1997, Serum and mucosal antibody isotype responses to M-like protein (SeM) of Streptococcus equi in convalescent and vaccinated horses. Vet Immunol Immunopathol 59:239-251.
9. Sweeney C: 1996, Strangles: Streptococcus equi infection in horses. Equine Vet Educ 8:317-322.
10. Sweeney CR, Benson CE, Whitlock RH, et al.: 1989, Description of an epizootic and persistence of Streptococcus equi infections in horses. J Am Vet Med Assoc 194:1281-1285.
11. Sweeney CR, Timoney JF, Newton JR, Hines MT: 2005, Streptococcus equi infections in horses: guidelines for treatment, control, and prevention of strangles. J Vet Intern Med 19:123-124.
12. Timoney JF, Artiushin SC, Boschwitz JS: 1997, Comparison of the sequences and functions of Streptococcus equi M like proteins Se Mans SzPSe. Infect Immun 65:3600-3605.
13. Timoney JF, Sheoran A, Artiushin S: 1998, Detection of strangles carriers [letter]. Vet Rec 142:648.
14. Verheryen K, Newton J, Talbot N, et al.: 2000, Elimination of guttural pouch infection and inflammation in asymptomatic carriers of Streptococcus equi. Equine Vet J 32:27-32.
15. Waller AS, Jolley KA: 2007, Getting a grip on strangles: recent progress towards improved diagnostics and vaccines. Vet J 173:492-501.
16. Wood JL, Dunn K, Chanter N, DeBrauwere N: 1993, Persistent infection with Streptococcus equi in the epidemiology of strangles [letter]. Vet Rec 133:375.