A captured viral interleukin 10 gene with cellular exon structure

Journal of General Virology

Volumn 89, Issue 10, 2008, Pages 2447-2455

  Jayawardane, Gamini ^a   Russell, George C ^b   Thomson, Jackie ^b   Deane, David ^b   Cox, Helen ^a   Gatherer, Derek ^c   Ackermann, Matthias ^d   Haig, David M ^b,e   Stewart, James P ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b MOREDUN RESEARCH INSTITUTE   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; GLYCOSYLATED PROTEIN; INTERLEUKIN 10; MACROPHAGE INFLAMMATORY PROTEIN; SIGNAL PEPTIDASE; PROTEIN; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CELL PROLIFERATION; CELL SIZE; CELL STRUCTURE; CONTROLLED STUDY; ENZYME SYNTHESIS; EXON; GENETIC VARIABILITY; HERPES SIMPLEX VIRUS 2; HUMAN; INTRON; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN SECRETION; VIRUS VIRULENCE; ANIMAL; CATTLE; CELL LINE; CHEMISTRY; DNA SEQUENCE; GENETICS; HERPES VIRUS; IMMUNOLOGY; MAST CELL; METABOLISM; MOLECULAR GENETICS; SHEEP; VIROLOGY;

HERPESVIRIDAE; OVINE HERPESVIRUS 2; OVIS;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; CELL LINE; EXONS; GAMMAHERPESVIRINAE; INTERLEUKIN-10; MAST CELLS; MOLECULAR SEQUENCE DATA; PROTEINS; SEQUENCE ANALYSIS, DNA; SHEEP; VIRAL PROTEINS;

EID: 54449095148     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.2008/001743-0     Document Type: Article

References (48)

1. Altschul, S. F., Gish, W., Miller, W., Myers, E. W. & Lipman, D. J. 1990). Basic local alignment search tool. J Mol Biol 215, 403-410.
2. Baxter, S. I., Pow, I., Bridgen, A. & Reid, H. W. (1993). PCR detection of the sheep-associated agent of malignant catarrhal fever. Arch Virol 132, 145-159.
3. Brunovskis, P. & Kung, H. J. (1995). Retrotransposition and herpesvirus evolution. Virus Genes 11, 259-270.
4. Bugert, J. J. & Darai, G. (2000). Poxvirus homologues of cellular genes. Virus Genes 21, 111-133.
5. Buxton, D., Reid, H. W., Finlayson, J., Pow, I. & Berrie, E. (1985). Transmission of a malignant catarrhal fever-like syndrome to sheep: preliminary experiments. Res Vet Sci 38, 22-29.
6. Chaston, T. B. & Lidbury, B. A. (2001). Genetic 'budget' of viruses and the cost to the infected host: a theory on the relationship between the genetic capacity of viruses, immune evasion, persistence and disease. Immunol Cell Biol 79, 62-66.
7. Ding, Y., Qin, L., Kotenko, S. V., Pestka, S. & Bromberg, J. S. (2000). A single amino acid determines the immunostimulatory activity of interleukin 10. J Exp Med 191, 213-224.
8. Edgar, R. C. (2004). MUSCLE: a multiple sequence alignment method with reduced time and space complexity. BMC Bioinformatics 5, 113.
9. Ehlers, B., Dural, G., Yasmum, N., Lembo, T., de Thoisy, B., Ryser-Degiorgis, M. P., Ulrich, R. G. & McGeoch, D. J. (2008). Novel mammalian herpesviruses and lineages within the Gammaherpesvirinae: cospeciation and interspecies transfer. J Virol 82, 3509-3516.
10. Emanuelsson, O., Brunak, S., von Heijne, G. & Nielsen, H. (2007). Locating proteins in the cell using TargetP, SignalP and related tools. Nat Protoc 2, 953-971.
11. Ensser, A., Pflanz, R. & Fleckenstein, B. (1997). Primary structure of the alcelaphine herpesvirus 1 genome. J Virol 71, 6517-6525.
12. Entrican, G., Wilkie, R., McWaters, P., Scheerlinck, J., Wood, P. R. & Brown, J. (1999). Cytokine release by ovine macrophages following infection with Chlamydia psittaci. Clin Exp Immunol 117, 309-315.
13. Gulley, M. L., Raphael, M., Lutz, C. T., Ross, D. W. & Raab-Traub, N. (1992). Epstein-Barr virus integration in human lymphomas and lymphoid cell lines. Cancer 70, 185-191.
14. + T cells during orf virus reinfection. J Gen Virol 77, 953-961.
15. Haig, D. M., Thomson, J., McInnes, C. J., Deane, D. L., Anderson, I. E., McCaughan, C. A., Imlach, W., Mercer, A. A., Howard, C. J. & Fleming, S. B. (2002). A comparison of the anti-inflammatory and immunostimulatory activities of orf virus and ovine interleukin-10. Virus Res 90, 303-316.
16. Hart, J., Ackermann, M., Jayawardane, G., Russell, G., Haig, D. M., Reid, H. & Stewart, J. P. (2007). Complete sequence and analysis of the ovine herpesvirus 2 genome. J Gen Virol 88, 28-39.
17. Henderson, A., Ripley, S., Heller, M. & Kieff, E. (1983). Chromosome site for Epstein-Barr virus DNA in a Burkitt tumor cell line and in lymphocytes growth-transformed in vitro. Proc Natl Acad Sci U S A 80, 1987-1991.
18. Holzerlandt, R., Orengo, C., Kellam, P. & Alba, M. M. (2002). Identification of new herpesvirus gene homologs in the human genome. Genome Res 12, 1739-1748.
19. Hughes, A. L. (2002). Origin and evolution of viral interleukin-10 and other DNA virus genes with vertebrate homologues. J Mol Evol 54, 90-101.
20. Jenkins, C., Abendroth, A. & Slobedman, B. (2004). A novel viral transcript with homology to human interleukin-10 is expressed during latent human cytomegalovirus infection. J Virol 78, 1440-1447.
21. Jones, B. C., Logsdon, N. J., Josephson, K., Cook, J., Barry, P. A. & Walter, M. R. (2002). Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1. Proc Natl Acad Sci U S A 99, 9404-9409.
22. Josephson, K., Logsdon, N. J. & Walter, M. R. (2001). Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site. Immunity 15, 35-46.
23. Josephson, K., Jones, B. C., Walter, L. J., DiGiacomo, R., Indelicato, S. R. & Walter, M. R. (2002). Noncompetitive antibody neutralization of IL-10 revealed by protein engineering and X-ray crystallography. Structure 10, 981-987.
24. Katoh, K., Kuma, K., Toh, H. & Miyata, T. (2005). MAFFT version 5: improvement in accuracy of multiple sequence alignment. Nucleic Acids Res 33, 511-518.
25. Kotenko, S. V., Saccani, S., Izotova, L. S., Mirochnitchenko, O. V. & Pestka, S. (2000). Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10). Proc Natl Acad Sci U S A 97, 1695-1700.
26. Kurilla, M. G., Swaminathan, S., Welsh, R. M., Kieff, E. & Brutkiewicz, R. R. (1993). Effects of virally expressed interleukin-10 on vaccinia virus infection in mice. J Virol 67, 7623-7628.
27. Lockridge, K. M., Zhou, S. S., Kravitz, R. H., Johnson, J. L., Sawai, E. T., Blewett, E. L. & Barry, P. A. (2000). Primate cytomegaloviruses encode and express an IL-10-like protein. Virology 268, 272-280.
28. McGeoch, D. J. (2001). Molecular evolution of the γ- Herpesvirinae. Philos Trans R Soc Lond B Biol Sci 356, 421-435.
29. McGeoch, D. J. & Davison, A. J. (1999). The descent of human herpesvirus 8. Semin Cancer Biol 9, 201-209.
30. McGeoch, D. J., Rixon, F. J. & Davison, A. J. (2006). Topics in herpesvirus genomics and evolution. Virus Res 117, 90-104.
31. Moore, K. W., Vieira, P., Fiorentino, D. F., Trounstine, M. L., Khan, T. A. & Mosmann, T. R. (1990). Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI. Science 248, 1230-1234.
32. Mosmann, T. R. (1994). Properties and functions of interleukin-10. Adv Immunol 56, 1-26.
33. Norman, J. A., Hobart, P., Manthorpe, M., Felgner, P. & Wheeler, C. (1997). Development of improved vectors for DNA-based immunization and other gene therapy applications. Vaccine 15, 801-803.
34. Notredame, C. & Suhre, K. (2004). Computing multiple sequence/ structure alignments with the T-coffee package. Curr Protoc Bioinformatics Chapter 3, Unit3 8.
35. Reid, H. W. & Buxton, D. (1989). Malignant catarrhal fever and the gammaherpesvirinae of Bovidae. In Herpesvirus Diseases of Cattle, Horses and Pigs, pp. 116-162. Edited by G. Wittman. London: Kluwer Academic.
36. Rode, H. J., Janssen, W., Rosen-Wolff, A., Bugert, J. J., Thein, P., Becker, Y. & Darai, G. (1993). The genome of equine herpesvirus type 2 harbors an interleukin 10 (IL10)-like gene. Virus Genes 7, 111-116.
37. Ronquist, F. & Huelsenbeck, J. P. (2003). MrBayes 3: Bayesian phylogenetic inference under mixedmodels. Bioinformatics 19, 1572-1574.
38. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989). Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
39. Schlaak, J. F., Schmitt, E., Huls, C., Meyer zum Buschenfelde, K. H. & Fleischer, B. (1994). A sensitive and specific bioassay for the detection of human interleukin-10. J Immunol Methods 168, 49-54.
40. Shackelton, L. A. & Holmes, E. C. (2004). The evolution of large DNA viruses: combining genomic information of viruses and their hosts. Trends Microbiol 12, 458-465.
41. Stewart, J. P. & Rooney, C. M. (1992). The interleukin-10 homolog encoded by Epstein-Barr virus enhances the reactivation of virus-specific cytotoxic T cell and HLA-unrestricted killer cell responses. Virology 191, 773-782.
42. Stewart, J. P., Janjua, N. J., Pepper, S. D., Bennion, G., Mackett, M., Allen, T., Nash, A. A. & Arrand, J. R. (1996). Identification and characterization of murine gammaherpesvirus 68 gp150: a virion membrane glycoprotein. J Virol 70, 3528-3535.
43. Taus, N. S., Herndon, D. R., Traul, D. L., Stewart, J. P., Ackermann, M., Li, H., Knowles, D. P., Lewis, G. S. & Brayton, K. A. (2007). Comparison of ovine herpesvirus 2 genomes isolated from domestic sheep (Ovis aries) and a clinically affected cow (Bos bovis). J Gen Virol 88, 40-45.
44. Thompson, J. D., Higgins, D. G. & Gibson, T. J. (1994). CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22, 4673-4680.
45. Thonur, L., Russell, G. C., Stewart, J. P. & Haig, D. M. (2006). Differential transcription of ovine herpesvirus 2 genes in lymphocytes from reservoir and susceptible species. Virus Genes 32, 27-35.
46. Walter,M. R. & Nagabhushan, T. L. (1995). Crystal structure of interleukin 10 reveals an interferon gamma-like fold. Biochemistry 34, 12118-12125.
47. Yang, Z. (2007). PAML 4: phylogenetic analysis by maximum likelihood. Mol Biol Evol 24, 1586-1591.
48. Zdanov, A., Schalk-Hihi, C., Menon, S., Moore, K. W. & Wlodawer, A. (1997). Crystal structure of Epstein-Barr virus protein BCRF1, a homolog of cellular interleukin-10. J Mol Biol 268, 460-467.