Characterization of ADAR1-mediated modulation of gene expression

Biochemical and Biophysical Research Communications

Volumn 377, Issue 1, 2008, Pages 170-175

  Gommans, Willemijn M ^a   Maas, Stefan ^a  

^a LEHIGH UNIVERSITY   (United States)

Author keywords

ADAR; Adenosine deamination; dsRNA specific adenosine deaminase; Inosine; Reporter gene expression; RNA editing

Indexed keywords

PROTEIN; PROTEIN ADAR1; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE INDUCTION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; RNA EDITING; TRANSGENE;

ADENOSINE DEAMINASE; GENE EXPRESSION; GENES, REPORTER; HELA CELLS; HUMANS; LUCIFERASES; PLASMIDS; RNA EDITING; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 54449092760     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.09.109     Document Type: Article

References (22)

1. Bass B.L. RNA editing by adenosine deaminases that act on RNA. Annu. Rev. Biochem. 71 (2002) 817-846
2. Gommans W.M., Dupuis D.E., McCane J.E., Tatalias N.E., and Maas S. Diversifying exon code through A-to-I RNA editing. In: Smith H.C. (Ed). RNA and DNA Editing (2008), Wiley & Sons, Inc., New York p. 27
3. Gommans W.M., Tatalias N.E., Sie C., Dupuis D., Vendetti N., Smith L., Kaushal R., and Maas S. Screening of human SNP database identifies recoding sites of A-to-I RNA editing. RNA 14 (2008) 11
4. Nishikura K. Editor meets silencer: crosstalk between RNA editing and RNA interference. Nat. Rev. Mol. Cell Biol. 7 (2006) 919-931
5. Rueter S.M., Dawson T.R., and Emeson R.B. Regulation of alternative splicing by RNA editing. Nature 399 (1999) 75-80
6. Prasanth K.V., Prasanth S.G., Xuan Z., Hearn S., Freier S.M., Bennett C.F., Zhang M.Q., and Spector D.L. Regulating gene expression through RNA nuclear retention. Cell 123 (2005) 249-263
7. Athanasiadis A., Rich A., and Maas S. Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome. PLoS Biol. 2 (2004) e391
8. Kim D.D., Kim T.T., Walsh T., Kobayashi Y., Matise T.C., Buyske S., and Gabriel A. Widespread RNA editing of embedded alu elements in the human transcriptome. Genome Res. 14 (2004) 1719-1725
9. Levanon E.Y., Eisenberg E., Yelin R., Nemzer S., Hallegger M., Shemesh R., Fligelman Z.Y., Shoshan A., Pollock S.R., Sztybel D., Olshansky M., Rechavi G., and Jantsch M.F. Systematic identification of abundant A-to-I editing sites in the human transcriptome. Nat. Biotechnol. 22 (2004) 1001-1005
10. Melcher T., Maas S., Herb A., Sprengel R., Higuchi M., and Seeburg P.H. RED2 a brain-specific member of the RNA-specific adenosine deaminase family. J. Biol. Chem. 271 (1996) 31795-31798
11. Melcher T., Maas S., Herb A., Sprengel R., Seeburg P.H., and Higuchi M. A mammalian RNA editing enzyme. Nature 379 (1996) 460-464
12. George C.X., and Samuel C.E. Human RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the other interferon inducible. Proc. Natl. Acad. Sci. USA 96 (1999) 4621-4626
13. Higuchi M., Single F.N., Kohler M., Sommer B., Sprengel R., and Seeburg P.H. RNA editing of AMPA receptor subunit GluR-B: a base-paired intron-exon structure determines position and efficiency. Cell 75 (1993) 1361-1370
14. Bhalla T., Rosenthal J.J., Holmgren M., and Reenan R. Control of human potassium channel inactivation by editing of a small mRNA hairpin. Nat. Struct. Mol. Biol. 11 (2004) 950-956
15. Burns C.M., Chu H., Rueter S.M., Hutchinson L.K., Canton H., Sanders-Bush E., and Emeson R.B. Regulation of serotonin-2C receptor G-protein coupling by RNA editing. Nature 387 (1997) 303-308
16. Vitali P., Basyuk E., Le Meur E., Bertrand E., Muscatelli F., Cavaille J., and Huttenhofer A. ADAR2-mediated editing of RNA substrates in the nucleolus is inhibited by C/D small nucleolar RNAs. J. Cell Biol. 169 (2005) 745-753
17. Yang W., Chendrimada T.P., Wang Q., Higuchi M., Seeburg P.H., Shiekhattar R., and Nishikura K. Modulation of microRNA processing and expression through RNA editing by ADAR deaminases. Nat. Struct. Mol. Biol. 13 (2006) 13-21
18. Maas S., Patt S., Schrey M., and Rich A. Underediting of glutamate receptor GluR-B mRNA in malignant gliomas. Proc. Natl. Acad. Sci. USA 98 (2001) 14687-14692
19. Lai F., Drakas R., and Nishikura K. Mutagenic analysis of double-stranded RNA adenosine deaminase, a candidate enzyme for RNA editing of glutamate-gated ion channel transcripts. J. Biol. Chem. 270 (1995) 17098-17105
20. Nie Y., Ding L., Kao P.N., Braun R., and Yang J.H. ADAR1 interacts with NF90 through double-stranded RNA and regulates NF90-mediated gene expression independently of RNA editing. Mol. Cell. Biol. 25 (2005) 6956-6963
21. O'Connell M.A., Krause S., Higuchi M., Hsuan J.J., Totty N.F., Jenny A., and Keller W. Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase. Mol. Cell. Biol. 15 (1995) 1389-1397
22. Samuel C.E. Antiviral actions of interferons. Clin. Microbiol. Rev. 14 (2001) 778-809 table of contents